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Medicine

FDA Approves Mixing COVID Vaccines (apnews.com) 303

U.S. regulators on Wednesday signed off on extending COVID-19 boosters to Americans who got the Moderna or Johnson & Johnson vaccine and said anyone eligible for an extra dose can get a brand different from the one they received initially. The Associated Press reports: The Food and Drug Administration's decisions mark a big step toward expanding the U.S. booster campaign, which began with extra doses of the Pfizer vaccine last month. But before more people roll up their sleeves, the Centers for Disease Control and Prevention will consult an expert panel later this week before finalizing official recommendations for who should get boosters and when.

The latest moves would expand by tens of millions the number of Americans eligible for boosters and formally allow "mixing and matching" of shots -- making it simpler to get another dose, especially for people who had a side effect from one brand but still want the proven protection of vaccination. Specifically, the FDA authorized a third Moderna shot for seniors and others at high risk from COVID-19 because of their health problems, jobs or living conditions -- six months after their last shot. One big change: Moderna's booster will be half the dose that's used for the first two shots, based on company data showing that was plenty to rev up immunity again. For J&J's single-shot vaccine, the FDA said all U.S. recipients should get a second dose at least two months following their initial vaccination.

Medicine

US Surgeons Successfully Test Pig Kidney Transplant In Human Patient (reuters.com) 66

For the first time, a pig kidney has been transplanted into a human without triggering immediate rejection by the recipient's immune system, a potentially major advance that could eventually help alleviate a dire shortage of human organs for transplant. Reuters reports: The procedure done at NYU Langone Health in New York City involved use of a pig whose genes had been altered so that its tissues no longer contained a molecule known to trigger almost immediate rejection. The recipient was a brain-dead patient with signs of kidney dysfunction whose family consented to the experiment before she was due to be taken off of life support, researchers told Reuters. For three days, the new kidney was attached to her blood vessels and maintained outside her body, giving researchers access to it.

Test results of the transplanted kidney's function "looked pretty normal," said transplant surgeon Dr. Robert Montgomery, who led the study. The kidney made "the amount of urine that you would expect" from a transplanted human kidney, he said, and there was no evidence of the vigorous, early rejection seen when unmodified pig kidneys are transplanted into non-human primates. The recipient's abnormal creatinine level - an indicator of poor kidney function - returned to normal after the transplant, Montgomery said.

Montgomery's team theorized that knocking out the pig gene for a carbohydrate that triggers rejection - a sugar molecule, or glycan, called alpha-gal - would prevent the problem. The genetically altered pig, dubbed GalSafe, was developed by United Therapeutics Corp's Revivicor unit. It was approved by the U.S. Food and Drug Administration in December 2020, for use as food for people with a meat allergy and as a potential source of human therapeutics. Other researchers are considering whether GalSafe pigs can be sources of everything from heart valves to skin grafts for human patients.

Social Networks

Doctors Blame TikTok For Surge In Teen Girls Experiencing Tics (people.com) 60

An anonymous reader quotes a report from People: Doctors around the world are seeing a rise in cases of tic-like behaviors in teen girls, which they believe could be caused by watching TikTok videos about Tourette syndrome. Pediatric hospitals have reported an increase in teen girls coming in after developing tics, sudden twitches or noises that are a common symptom of Tourette syndrome, during the pandemic. The sudden rise is unusual, with tics typically occurring in boys, not girls. Experts in the U.S., Canada, the U.K. and Australia studied the patients for months and consulted between hospitals, finding that the common factor between the girls was an interest in watching TikTok videos from influencers who said they have Tourette syndrome, The Wall Street Journal reported.

According to the outlet, Texas Children's Hospital said they've had around 60 teens come in with tics since March 2020, compared to just one or two a year before then, while at Johns Hopkins University Tourette's Center, the number of patients reporting tic-like behaviors has jumped from 2 to 3% a year to 10 to 20%. And Rush University Medical Center in Chicago had 20 patients with tics over just four months this year, compared to 10 all of last year. Researchers from pediatric hospitals around the world found that referrals for tic-like behaviors soared during the pandemic, especially in girls aged 12 to 25, they wrote in a study published in August in the journal Movement Disorders. Since March 2020, referrals in the U.S., Canada, the U.K., Germany and Australia went from 1 to 2% to 20 to 35%. The researchers wrote that they've seen a "similarity between the tics or tic-like behaviors shown on social media and the tic-like behaviors of this group of patients."
Another group of doctors say they "believe this to be an example of mass sociogenic illness," where people are copying the behaviors they see in the videos. Doctors recommend therapy to treat kids experiencing these symptoms. They also advise parents to require their teens to "take a social media break or block Tourette videos on their TikTok account," adds the report.
Medicine

Homeopathy Doesn't Work. So Why Do So Many Germans Believe in It? (bloomberg.com) 221

How Natalie Grams, who once abandoned her medical education to study alternative therapies, became Germany's most prominent homeopathy skeptic. From a report: The pseudoscience of homeopathy was invented in Germany in the 18th century by a maverick physician named Samuel Hahnemann. His theory was based on the ancient principle of like cures like -- akin to the mechanism behind vaccines. The remedies Hahnemann developed, meant to help the body heal on its own, originate as substances that with excess exposure (like pollen) can make a patient ill (in this case, with hay fever) -- or kill them: Arsenic is used as a treatment for digestive problems, and the poisonous plant belladonna is meant to counteract pain and swelling. These substances are diluted -- again and again -- and shaken vigorously in a process called "potentization" or "dynamization." The resultant remedies typically contain a billionth, trillionth, orâ...âwellâ...âa zillionth (10 to the minus 60th, if you're counting) of the original substance.

Today, homeopathy is practiced worldwide, particularly in Britain, India, the U.S. -- where there's a monument to Hahnemann on a traffic circle six blocks north of the White House -- and, especially, Germany. Practitioners, however, differ greatly in their approach. Some only prescribe remedies cataloged in homeopathic reference books. Others take a more metaphoric bent, offering treatments that contain a fragment of the Berlin Wall to cure feelings of exclusion and loneliness or a powder exposed to cellphone signals as protection from radiation emitted by mobile handsets. Grams, the daughter of a chemist, first turned to homeopathy in 2002. While she was attending medical school to become a surgeon, a highway accident left her car in the ditch with the windshield shattered. Grams walked away unhurt, but she soon began to suffer from heart palpitations, panic attacks, and fainting spells that doctors couldn't explain. Her roommate suggested she visit a heilpraktiker, a type of German naturopath that offers alternative therapies ranging from acupuncture and massage to reiki and homeopathy.

Homeopaths typically spend a lot of time with patients, asking not just about symptoms but also about emotions, work, and relationships. This is all meant to find the root cause of a patient's suffering and is part of its appeal. The heilpraktiker asked Grams about her feelings and the accident, things she hadnâ(TM)t spoken about with her doctors -- or anyone -- thinking they weren't important in understanding what was wrong. The heilpraktiker prescribed her belladonna globules and recommended she visit a trauma therapist. Steadily, her symptoms fell away. She was healed. Soon after, Grams dropped the idea of becoming a surgeon, opting for a future as a general practitioner while taking night courses in alternative therapies. After completing her medical degree, she began a five-year residency to qualify as a GP. But three years in, Grams abandoned conventional medicine and began an apprenticeship with a homeopath near Heidelberg.

Medicine

The FDA Wants You To Be Able To Buy a Hearing Aid Without a Prescription (npr.org) 76

People with mild or moderate hearing loss could soon be able to buy hearing aids without a medical exam or special fitting, under a new rule being proposed by the Food and Drug Administration. The agency says 37.5 million American adults have difficulties hearing. From a report: "Today's move by FDA takes us one step closer to the goal of making hearing aids more accessible and affordable for the tens of millions of people who experience mild to moderate hearing loss," Health and Human Services Secretary Xavier Becerra said as he announced the proposed rule on Tuesday. There is no timeline yet for when consumers might be able to buy an FDA-regulated over-the-counter hearing aid. The proposed rule is now up for 90 days of public comment. The Hearing Loss Association of America, a consumer advocacy group, welcomed the proposal. "This is one step closer to seeing OTC hearing devices on the market," Barbara Kelley, HLAA's executive director said in an email to NPR. "We hope adults will be encouraged to take that important first step toward good hearing health."
Earth

99.9% of Scientists Agree Climate Emergency Caused by Humans (theguardian.com) 281

knaapie writes: It may still be fuel for hot debate on social media, but 99.9% of scientist actually agree on the fact that humans are altering the climate. The Guardian reports that the degree of scientific certainty about the impact of greenhouse gases is now similar to the level of agreement on evolution and plate tectonics, the authors say, based on a survey by Cornell University of nearly 90,000 climate-related studies. This means there is practically no doubt among experts that burning fossil fuels, such as oil, gas, coal, peat and trees, is heating the planet and causing more extreme weather.

"It is really case closed. There is nobody of significance in the scientific community who doubts human-cased climate change," said the lead author, Mark Lynas, a visiting fellow at Cornell University. In contrast, the paper cites a 2016 study by the Pew Research Center that found only 27% of US adults believed that "almost all" scientists agreed the climate emergency was caused by human activity. And according to the Center for American Progress, 30 US senators and 109 representatives "refuse to acknowledge the scientific evidence of human-caused climate change." Several big media organisations and social networks also promote climate-sceptical views that have little or no basis in science. Lynas said the study should encourage them to review their policies. "This puts the likes of Facebook and Twitter in a quandary. It is pretty similar to vaccine misinformation; they both lack a basis in science and they both have a destructive impact on society. Social networks that allow climate misinformation to spread need to look at their algorithms and policies or to be forced to do so by regulators."

Space

Star's Strange Path Around Black Hole Proves Einstein Right -- Again (science.org) 61

Albert Einstein's theory of general relativity has aced another test. From a report: Following nearly 3 decades of monitoring, researchers have detected a subtle shift in the orbit of the closest known star to the supermassive black hole at the center of the Milky Way -- and the movement matches Einstein's theory precisely. The star, known as S2, follows an elliptical 16-year orbit. It made a close approach -- within 20 billion kilometers -- to our black hole, Sagittarius A*, last year. If Isaac Newton's classic description of gravity holds true, S2 should then continue along exactly the same path through space as on its previous orbit. But it didn't. Instead, it followed a slightly diverging path, the axis of its ellipse shifting slightly, a team using the European Southern Observatory's Very Large Telescope reports today in Astronomy & Astrophysics. The phenomenon, known as Schwarzschild precession, would, in time, cause S2 to trace out a spirographlike flower pattern in space -- as general relativity predicts.
Power

Radiant Aims To Replace Diesel Generators With Small Nuclear Reactors (newatlas.com) 266

An anonymous reader quotes a report from New Atlas: California company Radiant has secured funding to develop a compact, portable, "low-cost" one-megawatt nuclear micro-reactor that fits in a shipping container, powers about 1,000 homes and uses a helium coolant instead of water. Founded by ex-SpaceX engineers, who decided the Mars colony power sources they were researching would make a bigger impact closer to home, Radiant has pulled in $1.2 million from angel investors to continue work on its reactors, which are specifically designed to be highly portable, quick to deploy and effective wherever they're deployed; remote communities and disaster areas are early targets.

The military is another key market here; a few of these could power an entire military base in a remote area for four to eight years before expending its "advanced particle fuel," eliminating not just the emissions of the current diesel generators, but also the need to constantly bring in trucks full of fuel for this purpose. Those trucks will still have to run -- up until the point where the military ditches diesel in all its vehicles -- but they'll be much less frequent, reducing a significant risk for transport personnel. Radiant says its fuel "does not melt down, and withstands higher temperatures when compared to traditional nuclear fuels." Using helium as the coolant "greatly reduces corrosion, boiling and contamination risks," and the company says it's received provisional patents for ideas it's developed around refueling the reactors and efficiently transporting heat out of the reactor core.

Science

MIT Researchers Create 'Robotic' Textiles To Make Breath-Regulating Garments (mit.edu) 18

A new kind of fiber developed by researchers at MIT and in Sweden can be made into clothing that senses how much it is being stretched or compressed, and then provides immediate tactile feedback in the form of pressure, lateral stretch, or vibration. Such fabrics, the team suggests, could be used in garments that help train singers or athletes to better control their breathing, or that help patients recovering from disease or surgery to recover their breathing patterns. From a report: The multilayered fibers contain a fluid channel in the center, which can be activated by a fluidic system. This system controls the fibers' geometry by pressurizing and releasing a fluid medium, such as compressed air or water, into the channel, allowing the fiber to act as an artificial muscle. The fibers also contain stretchable sensors that can detect and measure the degree of stretching of the fibers. The resulting composite fibers are thin and flexible enough to be sewn, woven, or knitted using standard commercial machines. The fibers [are] dubbed OmniFibers [...].

The new fiber architecture has a number of key features. Its extremely narrow size and use of inexpensive material make it relatively easy to structure the fibers into a variety of fabric forms. It's also compatible with human skin, since its outer layer is based on a material similar to common polyester. And, its fast response time and the strength and variety of the forces it can impart allow for a rapid feedback system for training or remote communications using haptics (based on the sense of touch). As an initial test application of the material, the team made a type of undergarment that singers can wear to monitor and play back the movement of respiratory muscles, to later provide kinesthetic feedback through the same garment to encourage optimal posture and breathing patterns for the desired vocal performance. Though this initial testing is in the context of vocal pedagogy, the same approach could be used to help athletes to learn how best to control their breathing in a given situation, based on monitoring accomplished athletes as they carry out various activities and stimulating the muscle groups that are in action. Eventually, the hope is that such garments could also be used to help patients regain healthy breathing patterns after major surgery or a respiratory disease such as Covid-19, or even as an alternative treatment for sleep apnea.

Space

A Meteorite Crashed Through Somebody's Ceiling and Landed on Their Bed (chicagotribune.com) 197

The New York Times reports: Ruth Hamilton was fast asleep in her home in British Columbia when she awoke to the sound of her dog barking, followed by "an explosion." She jumped up and turned on the light, only to see a hole in the ceiling. Her clock said 11:35 p.m.

At first, Hamilton thought that a tree had fallen on her house. But, no, all the trees were there. She called 911 and, while on the phone with an operator, noticed a large charcoal gray object between her two floral pillows.

"Oh, my gosh," she recalled telling the operator, "there's a rock in my bed."

A meteorite, she later learned.

The 2.8-pound rock the size of a large man's fist had barely missed Hamilton's head, leaving "drywall debris all over my face," she said. Her close encounter on the night of Oct. 3 left her rattled, but it captivated the internet and handed scientists an unusual chance to study a space rock that had crashed to Earth.

"It just seems surreal," Hamilton said in an interview Wednesday. "Then I'll go in and look in the room and, yep, there's still a hole in my ceiling. Yep, that happened."

The Times reports that Peter Brown, a professor at the University of Western Ontario, places the odds of a meteor crashing into someone's bed at 1 in 100 billion.
Moon

The Moon Will Soon Have Its Own Internet (autoevolution.com) 59

"Humanity will return to the lunar surface in 2024 as part of the Artemis program," writes the Auto Evolution site. "However, before NASA begins shuttling people to our natural satellite, it has to build a network there that will go beyond Earth's low orbit and connect space to Earth in a sort of Internet connection..." The network's name? LunaNet: Astronauts will be able to use the LunaNet via numerous nodes and communicate with the crew on and around the Moon in the same manner that we use Wi-Fi here on Earth. In addition, missions using the network will have access to position and time signals, allowing astronauts and rovers to navigate the rugged lunar terrain and return to their base. LunaNet will also use space-weather instruments to identify potentially dangerous solar activity, such as flares that erupt from the Sun and send harsh radiation towards the astronauts. With this new connectivity, the crew can be directly alerted. This will cut down the time it takes for network management on Earth to do so. These warnings will be comparable to the ones we receive on our phones when there is hazardous weather. The architecture's capabilities will also include a lunar search and rescue capability...

Researchers could also use LunaNet antennas to peer into deep space and search for radio signals from distant celestial objects. Altogether, the architecture's capabilities will give scientists a new platform to test space theories, allowing them to extend their scientific knowledge. Recently, NASA released the "Draft LunaNet Interoperability Specification" in order to kickstart the development of this new "lunar internet." Technical discussions among industry experts from around the world are expected to follow.

United States

American Bumblebees Have Disappeared From 8 States and Could Face Extinction (usatoday.com) 131

Long-time Slashdot reader phalse phace quotes USA Today: The dwindling populations of the American bumblebee and their complete disappearance from eight states has led to a call for the bee to be placed under the Endangered Species Act before they face extinction.

Maine, Rhode Island, New Hampshire, Vermont, Idaho, North Dakota, Wyoming, and Oregon each have zero or close to zero American bumblebees left, according to a petition by the Center for Biological Diversity and Bombus Pollinators Association of Law Students...

Over the last two decades, the American bumblebee population has decreased by 89% across the U.S. New York had a decline of 99% and they disappeared from the northern part of Illinois that has seen a 74% decrease in population since 2004, the petition said.

Climate change, pesticides, disease, habitat loss and competition from honey bees are listed as driving the bee to extinction... The loss of the insect could cause serious repercussions to the environment and crop production due to them being essential pollinators in agriculture. If the American bumblebee is added to the endangered species list, it will join the rusty-patched bumblebee, and If granted federal protection, anyone found to have killed or harmed the bee could face up to $13,000 in fines.

Space

China Launches 6-Month Crewed Mission, Cements Position as Global Space Power (cnn.com) 69

"China launched a three-person crew into space in the early hours of Saturday," reports CNN, calling it "a major step for the country's young space program, which is rapidly becoming one of the world's most advanced..." They will dock at China's new space station, Tiangong (which means Heavenly Palace), six and a half hours after launch. They will live and work at the station for 183 days, or just about six months... "This will certainly be their longest mission, which is quite impressive when you consider how early it is in their human spaceflight regimen," said Dean Cheng, senior research fellow at the Davis Institute for National Security and Foreign Policy.

This is the second crewed mission during the construction of the space station, which China plans to have fully crewed and operational by December 2022. The first crewed mission, a three-month stay by three other astronauts, was completed last month. Six more missions have been scheduled before the end of next year, including two crewed missions, two laboratory modules and two cargo missions. "For the Chinese, this is still early in their human spaceflight effort as they've been doing this for less than 20 years ... and for fewer than 10 missions," Cheng added. "In the past, the Chinese put up a crewed flight only once every two to three years. Now, they're sending them up every few months."

"If the Chinese maintain this pace ... it reflects a major shift in the mission tempo for their human spaceflight efforts...."

China successfully landed an exploratory rover on the moon last December and one on Mars in May. The first module of the Tiangong space station launched in April. Just last week, an international team of scientists released their findings from the moon rocks China brought back to Earth... "The European Space Agency, Russia, India, and Israel have suffered Moon or Mars probe failures in recent years; China succeeded with both on the first tries," David Burbach, associate professor of national security affairs at the US Naval War College, told CNN via email. Though the US still has the world's leading space program, he said, "there's no doubt that China is the world's Number 2 space power today."

China's ambitions span years into the future, with grand plans for space exploration, research and commercialization. One of the biggest ventures will be building a joint China-Russia research station on the moon's south pole by 2035 — a facility that will be open to international participation... Chinese astronauts have long been locked out of the International Space Station due to US political objections and legislative restrictions — which is why it has been a long-standing goal of China's to build a station of its own...

One reason space research cannot be divorced from terrestrial politics, and why the issue is so complicated, is because "the Chinese space program is heavily influenced, and its human and lunar programs are overseen, by the Chinese military," Cheng said. "Cooperating with China in space means cooperating with the Chinese military."

ISS

Russian Spacecraft's Thrusters Tilt the International Space Station - Again (space.com) 44

"Unplanned thruster firings by a Russian spacecraft briefly knocked the International Space Station off-kilter Friday, the second such incident in less than three months," reports Space.com: The spacecraft involved today was the Soyuz MS-18, which is scheduled to bring cosmonaut Oleg Novitskiy, film director Klim Shipenko and actor Yulia Peresild back to Earth early Sunday morning (Oct. 17)... "Within 30 minutes, flight controllers regained attitude control of the space station, which is now in a stable configuration," NASA officials wrote in an update this afternoon. "The crew was awake at the time of the event and was not in any danger."

The orbiting lab briefly tilted from its normal orientation this morning by 57 degrees, according to the Russian news agency Interfax, which cited communications between Novitskiy and Vladimir Solovyov, the flight director of the station's Russian segment.

Space station managers don't yet know what caused the anomalously long firing... It's also unclear why the MS-18's thrusters stopped firing, though the station's handlers have some ideas. "We think — and we haven't got confirmation — we think the thrusters stopped firing because they reached their prop[ellant] limit," NASA flight director Timothy Creamer told agency astronauts shortly after the thrusters shut down, according to The New York Times. "Moscow is checking into it and doing their data analysis."

Space

Astronomers Spot First Known Exoplanet To Survive Its Dying Star (theconversation.com) 12

"In our new paper, published in Nature, we report the discovery of the first known exoplanet to survive the death of its star without having its orbit altered by other planets moving around -- circling a distance comparable to those between the Sun and the Solar System planets," writes one of the study's authors, Dimitri Veras, in an article for The Conversation. From the report: This new exoplanet, which we discovered with the Keck Observatory in Hawaii, is particularly similar to Jupiter in both mass and orbital separation, and provides us with a crucial snapshot into planetary survivors around dying stars. A star's transformation into a white dwarf involves a violent phase in which it becomes a bloated "red giant," also known as a "giant branch" star, hundreds of times bigger than before. We believe that this exoplanet only just survived: if it was initially closer to its parent star, it would have been engulfed by the star's expansion. When the Sun eventually becomes a red giant, its radius will actually reach outwards to Earth's current orbit. That means the Sun will (probably) engulf Mercury and Venus, and possibly the Earth -- but we are not sure.

Jupiter, and its moons, have been expected to survive, although we previously didn't know for sure. But with our discovery of this new exoplanet, we can now be more certain that Jupiter really will make it. Moreover, the margin of error in the position of this exoplanet could mean that it is almost half as close to the white dwarf as Jupiter currently is to the Sun. If so, that is additional evidence for assuming that Jupiter, and Mars, will make it. So could any life survive this transformation? A white dwarf could power life on moons or planets that end up being very close to it (about one-tenth the distance between the Sun and Mercury) for the first few billion years. After that, there wouldn't be enough radiation to sustain anything. [...]

The new white dwarf exoplanet was found with what is known as the microlensing detection method. This looks at how light bends due to a strong gravitational field, which happens when a star momentarily aligns with a more distant star, as seen from Earth. The gravity from the foreground star magnifies the light from the star behind it. Any planets orbiting the star in the foreground will bend and warp this magnified light, which is how we can detect them. The white dwarf we investigated is one-quarter of the way towards the centre of the Milky Way galaxy, or about 6,500 light years away from our Solar System, and the more distant star is in the centre of the galaxy.

Medicine

Drones Have Now Been Used To Deliver Lungs For Medical Transplant (extremetech.com) 22

An anonymous reader quotes a report from ExtremeTech: The world's first drone delivery of lungs has gone down in history as a success. Unither Bioelectronique, a bioengineering firm focused on organ transportation, recently completed a "proof-of-concept" flight in which a pair of human lungs were shipped via drone to the transplant site in about six minutes. The lungs were flown from the Toronto Western Hospital to Toronto General Hospital, where Dr. Shaf Keshavjee, surgeon-in-chief of Canada's University Health Network, received the cargo at about 1 a.m. He needed the lungs for a transplant he was performing that very day on a male engineer who'd soon become the first transplant patient to receive his "new" lungs by drone.

Though the circumstances of the trip were urgent, the trip itself was 18 months in the making. Organs have been shipped by drone before, but lungs are particularly sensitive to environmental shifts during transport, with a majority of donated lungs rendered unusable by insufficient oxygenation. In order to make the trip worthwhile, engineers at Unither Bioelectronique had to design a lightweight carbon fiber shipping container that could withstand vibrations and in-flight changes in elevation and barometric pressure. Preparation involved practice flights and drop tests using simulation lung packages. The drone and its container counterpart were fitted with a parachute and an advanced GPS system, as the drone would fly through the air unmanned.
"This innovation in the transportation of organs has the potential to significantly increase the transfer efficiency between donors and recipients, especially in congested urban areas," Unither Bioelectronique says of the trip on their website. "Through this project, we have established an important stepping stone for future organ delivery that ultimately will open the door for large-scale adoption of larger fully autonomous, electrically-powered, environmentally-friendly drones... for transplant across trans-continental distances."
Medicine

Chemicals Used In Packaging May Play Role In 100,000 US Deaths a Year (theguardian.com) 113

An anonymous reader quotes a report from The Guardian: The group of chemicals called phthalates, also known as plasticizers, may contribute to the early deaths of 91,000 to 107,000 older adults in the US each year, according to a new study. Adults between 55 and 64 with the highest concentrations of phthalates in their urine were more likely to die of any cause, especially heart disease, than adults with lesser exposure, according to the study published on Tuesday in the peer-reviewed journal Environmental Pollution. The study also estimated that this loss of life could cost the US between $40 billion and $47 billion each year. In the US, three types of phthalates have been restricted or banned in toys, but are less restricted in cosmetics and food packaging materials. Researchers said the study "focuses substantial urgency" in putting further limits on phthalates in food packaging materials and other consumer goods. Phthalates, a group of chemicals most commonly used to make plastic harder to break, can interfere with the function of hormones, and researchers plan to examine what role the chemical plays in hormone regulation and inflammation in the body. "Our research suggests that the toll of this chemical on society is much greater than we first thought," said the study's lead author, Dr Leonardo Trasande. "The evidence is undeniably clear that limiting exposure to toxic phthalates can help safeguard Americans' physical and financial wellbeing." He cautioned that the biological connection between phthalates and early deaths has not been established, so the study does not prove phthalates were the direct cause of these early deaths.
Earth

Countries Are Gathering In an Effort To Stop a Biodiversity Collapse (nytimes.com) 70

An anonymous reader quotes a report from The New York Times: As 20,000 government leaders, journalists, activists and celebrities from around the world prepare to descend on Glasgow for a crucial climate summit starting late this month, another high-level international environmental meeting got started this week. The problem it seeks to tackle: A rapid collapse of species and systems that collectively sustain life on earth. The stakes at the two meetings are equally high, many leading scientists say, but the biodiversity crisis has received far less attention. "If the global community continues to see it as a side event, and they continue thinking that climate change is now the thing to really listen to, by the time they wake up on biodiversity it might be too late," said Francis Ogwal, one of the leaders of the working group charged with shaping an agreement among nations. Because climate change and biodiversity loss are intertwined, with the potential for both win-win solutions and vicious cycles of destruction, they must be addressed together, scientists say. But their global summits are separate, and one overshadows the other.

This week, environment officials, diplomats and other observers from around the world gathered online, and a small group assembled in person in Kunming, China, for the meeting, the 15th United Nations biodiversity conference. The United States is the only country in the world besides the Vatican that is not a party to the underlying treaty, the Convention on Biological Diversity, a situation largely attributed to Republican opposition. American representatives participate on the sidelines of the talks, as do scientists and environmental advocates. Because of the pandemic, the conference has been broken into two parts. While this virtual portion was largely about drumming up political will, nations will meet again in China in the spring to ratify a series of targets aimed at tackling biodiversity loss. The aim will be to adopt a pact for nature akin to the Paris Agreement on climate change, said Elizabeth Maruma Mrema, the executive secretary of the convention.

Last year, officials reported that the world's nations largely failed to achieve the targets of the previous global agreement on biodiversity, made in 2010. If the new commitments are not translated into "effective policies and concrete actions," Ms. Mrema said this week at the meeting, "we risk repeating the failures of the last decade." The working draft includes 21 targets that act as a blueprint for reducing biodiversity loss. Many are concrete and measurable, others more abstract. None are easy. They include, in summary: Create a plan, across the entire land and waters of each country, to make the best decisions about where to conduct activities like farming and mining while also retaining intact areas; Ensure that wild species are hunted and fished sustainably and safely; Reduce agricultural runoff, pesticides and plastic pollution; Use ecosystems to limit climate change by storing planet-warming carbon in nature; Reduce subsidies and other financial programs that harm biodiversity by at least $500 billion per year, the estimated amount (PDF) that governments spend supporting fossil fuels and potentially damaging agricultural practices; and Safeguard at least 30 percent of the planet's land and oceans by 2030.

Medicine

Acer Launches Bacteria-Resistant PCs (arstechnica.com) 69

During its next@Acer event today, the company announced three new PCs -- a laptop, a two-in-one, and a tablet -- that will be joining its antimicrobial lineup. Ars Technica reports: Something is considered antimicrobial if it's capable of "destroying or inhibiting the growth of microorganisms, and especially pathogenic microorganisms." That means it fights disease-causing things you can't see. Acer claims its Antimicrobial 360 Design, as it brands the feature, fights germs in two ways. First, high-touch surfaces -- such as the chassis's exterior and hinge, the keyboard, the touchpad, and the fingerprint reader -- are coated with a silver-ion agent. For years, research has pointed to silver ions' ability to fight bacteria. As a more recent report published in ACS Applied Bio Materials explains, "They can readily adsorb to most biomolecules (DNA, membrane protein, enzymes, or intracellular cofactors) in bacteria to inactivate their functions." Acer's silver-ion agent is compliant with regulations from the Environmental Protection Agency and the Biocidal Products Regulation; it can cut the bacteria count to 1,000 after a 99.9 percent reduction, based on the International Organization for Standardization 22196 test protocol. The 22196 standard specifies methods for testing the "antibacterial activity of antibacterial-treated plastics and other non-porous surfaces of products."

The products also use Corning Gorilla Glass coated with the silver-ion product. "This is done via trace amounts of silver ions leaching to the glass surface to eliminate the surface bacteria, while still offering other benefits such as improved durability and improved scratch resistance," Acer said. Acer introduced new antimicrobial PCs to its lineup in 2020 but is still adding to the roster. The company sees its antimicrobial coating expanding even further "across multiple product lines," an Acer spokesperson told Ars.

Medicine

Aspirin Use To Prevent 1st Heart Attack or Stroke Should Be Curtailed, US Panel Says 87

Doctors should no longer routinely start most people who are at high risk of heart disease on a daily regimen of low-dose aspirin, according to new draft guidelines by a U.S. panel of experts. The New York Times reports: The proposed recommendation is based on mounting evidence that the risk of serious side effects far outweighs the benefit of what was once considered a remarkably cheap weapon in the fight against heart disease. The U.S. panel also plans to retreat from its 2016 recommendation to take baby aspirin for the prevention of colorectal cancer, guidance that was groundbreaking at the time. The panel said more recent data had raised questions about the benefits for cancer, and that more research was needed.

On the use of low-dose or baby aspirin, the recommendation by the U.S. Preventive Services Task Force would apply to people younger than 60 who were at high risk of heart disease and for whom a new daily regimen of the mild analgesic might have been a tool to prevent a first heart attack or stroke. The proposed guidelines would not apply to those already taking aspirin or those who have already had a heart attack. The U.S. task force also wants to strongly discourage anyone 60 and older from starting a low-dose aspirin regimen, citing concerns about the age-related heightened risk for life-threatening bleeding. The panel had previously recommended that people in their 60s who were at high risk for cardiovascular disease consult their doctors to make a decision. A low dose is 81 milligrams to 100 milligrams.

The task force proposals follow years of changes in advice by several leading medical organizations and federal agencies, some of which had already recommended limiting the use of low-dose aspirin as a preventive tool against heart disease and stroke. Aspirin inhibits the formation of blood clots that can block arteries, but studies have raised concerns that regular intake increases the risk of bleeding, especially in the digestive tract and the brain, dangers that increase with age. "There's no longer a blanket statement that everybody who's at increased risk for heart disease, even though they never had a heart attack, should be on aspirin," said Dr. Chien-Wen Tseng, a member of the national task force who is the research director of family medicine and community health at the University of Hawaii. "We need to be smarter at matching primary prevention to the people who will benefit the most and have the least risk of harms." Those who are already taking baby aspirin should talk to their doctor.

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