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Puzzle Games (Games)

NYTimes Files Copyright Takedown Against Hundreds of Wordle Clones (404media.co) 39

As reported by 404 Media, the New York Times has issued hundreds of copyright takedown requests against Wordle clones "in which it asserts not just ownership over the Wordle name but over the broad concepts and mechanics of the word game, which includes its '5x6 grid' and 'green tiles to indicate correct guesses.'" From the report: The Times filed at least three DMCA takedown requests with coders who have made clones of Wordle on GitHub. These include two in January and, crucially, a new DMCA filed this week against Chase Wackerfuss, the coder of a repository called âoeReactle,â which cloned Wordle in React JS (JavaScript). The most recent takedown request is critical because it not only goes after Reactle but anyone who has forked Reactle to create a different spinoff game; an archive of the Reactle code repository shows that it was forked 1,900 times to create a diverse set of games and spinoffs. These include Wordle clones in dozens of languages, crossword versions of Wordle, emoji and bird versions of world, poker and AI spinoffs, etc.

"I write to submit a revised DMCA Notice regarding an infringing repository (and hundreds of forked repositories) hosted by Github that instruct users how to infringe The New York Times Co.'s ('The Times') copyright in its immensely popular Wordle game and create knock-off copies of the same. Unfortunately, hundreds of individuals have followed these instructions and published infringing Wordle knock-off games that The Times has spent the past month removing, including off of Github's websites," the DMCA takedown request against Reactle reads. "The Times's Wordle copyright includes the unique elements of its immensely popular game, such as the 5x6 grid, green tiles to indicate correct guesses, yellow tiles to indicate the correct letter but the wrong place within the word, and the keyboard directly beneath the grid. This gameplay is copied exactly in the repository, and the owner instructs others how to knock off the game and create an identical word game," it adds.

The DMCA request then says that GitHub must delete forks of the repository, which it writes were "infringing to the same extent as the parent repository" and which it says were made in what was "clearly bad faith." [...] The DMCA takedown requests are particularly notable because they come at a time when the New York Times is financially thriving, while many of its competitors are losing money, laying people off, and shutting down. The Times is thriving in part because Wordle, the crossword puzzle, and its recipe apps are juggernauts. The company has been aggressively expanding its "Games" business with Wordle, Connections, and a brand new word search game called Strands.
The New York Times issued a statement in response: "The Times has no issue with individuals creating similar word games that do not infringe The Times's 'Wordle' trademarks or copyrighted gameplay. The Times took action against a GitHub user and others who shared his code to defend its intellectual property rights in Wordle. The user created a 'Wordle clone' project that instructed others how to create a knock-off version of The Times's Wordle game featuring many of the same copyrighted elements. As a result, hundreds of websites began popping up with knock-off 'Wordle' games that used The Times's 'Wordle' trademark and copyrighted gameplay without authorization or permission."
AMD

AMD Stops Certifying Monitors, TVs Under 144 Hz For FreeSync (arstechnica.com) 49

An anonymous reader quotes a report from Ars Technica: AMD announced this week that it has ceased FreeSync certification for monitors or TVs whose maximum refresh rates are under 144 Hz. Previously, FreeSync monitors and TVs could have refresh rates as low as 60 Hz, allowing for screens with lower price tags and ones not targeted at serious gaming to carry the variable refresh-rate technology. AMD also boosted the refresh-rate requirements for its higher AdaptiveSync tiers, FreeSync Premium and FreeSync Premium Pro, from 120 Hz to 200 Hz.

Here are the new minimum refresh-rate requirements for FreeSync, which haven't changed for laptops. AMD will continue supporting already-certified FreeSync displays even if they don't meet the above requirements. Interestingly, AMD's minimum refresh-rate requirements for TVs goes beyond 120 Hz, which many premium TVs max out at currently, due to the current-generation Xbox and PlayStation supporting max refresh rates of 120 frames per second (FPS). Announcing the changes this week in a blog post, Oguzhan Andic, AMD FreeSync and Radeon product marketing manager, claimed that the changes were necessary, noting that 60 Hz is no longer "considered great for gaming." Andic wrote that the majority of gaming monitors are 144 Hz or higher, compared to in 2015, when FreeSync debuted, and even 120 Hz was "a rarity."

AI

Dozens of Top Scientists Sign Effort To Prevent AI Bioweapons (nytimes.com) 53

An anonymous reader shares a report: Dario Amodei, chief executive of the high-profile A.I. start-up Anthropic, told Congress last year that new A.I. technology could soon help unskilled but malevolent people create large-scale biological attacks, such as the release of viruses or toxic substances that cause widespread disease and death. Senators from both parties were alarmed, while A.I. researchers in industry and academia debated how serious the threat might be. Now, over 90 biologists and other scientists who specialize in A.I. technologies used to design new proteins -- the microscopic mechanisms that drive all creations in biology -- have signed an agreement that seeks to ensure that their A.I.-aided research will move forward without exposing the world to serious harm.

The biologists, who include the Nobel laureate Frances Arnold and represent labs in the United States and other countries, also argued that the latest technologies would have far more benefits than negatives, including new vaccines and medicines. "As scientists engaged in this work, we believe the benefits of current A.I. technologies for protein design far outweigh the potential for harm, and we would like to ensure our research remains beneficial for all going forward," the agreement reads. The agreement does not seek to suppress the development or distribution of A.I. technologies. Instead, the biologists aim to regulate the use of equipment needed to manufacture new genetic material. This DNA manufacturing equipment is ultimately what allows for the development of bioweapons, said David Baker, the director of the Institute for Protein Design at the University of Washington, who helped shepherd the agreement.

Space

Astronomers Detect 'Waterworld With a Boiling Ocean' in Deep Space (theguardian.com) 25

Astronomers have observed a distant planet that could be entirely covered in a deep water ocean, in findings that advance the search for habitable conditions beyond Earth. From a report: The observations, by Nasa's James Webb space telescope (JWST), revealed water vapour and chemical signatures of methane and carbon dioxide in the atmosphere of the exoplanet, which is twice Earth's radius and about 70 light years away. This chemical mix is consistent with a water world where the ocean would span the entire surface, and a hydrogen-rich atmosphere, according to researchers from the University of Cambridge, although they do not envisage a balmy, inviting seascape. "The ocean could be upwards of 100 degrees [Celsius] or more," said Prof Nikku Madhusudhan, who led the analysis. At high atmospheric pressure, an ocean this hot could still be liquid, "but it's not clear if it would be habitable," he added.

This interpretation is favoured in a paper published in the journal Astronomy and Astrophysics Letters, but is disputed by a Canadian team that made additional observations of the same exoplanet, which is known as TOI-270 d. They detected the same atmospheric chemicals but argue the planet would be too hot for liquid water -- possibly 4,000C -- and instead would feature a rocky surface topped by an incredibly dense atmosphere of hydrogen and water vapour. Whichever view wins out, these latest observations showcase the stunning insights James Webb is giving into the nature of planets beyond our solar system. The telescope captures the starlight that has been filtered through the atmospheres of orbiting planets to give detailed breakdowns of the chemical elements present. From this, astronomers can build up a picture of conditions at a planet's surface -- and the likelihood of life being able to survive there.

Microsoft

Microsoft Sends OneDrive URL Upload Feature To the Cloud Graveyard (theregister.com) 13

Microsoft has abruptly pulled a feature from OneDrive that allows users to upload files to the cloud storage service directly from a URL. From a report: The feature turned up as a preview in 2021 and was intended for scenarios "where the file contents aren't available, or are expensive to transfer," according to Microsoft. It was particularly useful for mobile users, for whom uploading files directly through their apps could be costly. Much better to simply point OneDrive at a given URL and let it handle the upload itself.

However, the experimental feature never made it past the consumer version of OneDrive. It also didn't fit with Microsoft's "vision for OneDrive as a cloud storage service that syncs your files across devices." Indeed, the idea of hosing data into OneDrive from a remote source sits at odds with the file synchronization model being championed by Microsoft and conveniently available from macOS and Windows.

Apple

Apple Reinstates Epic Developer Account After Public Backlash for Retaliation (epicgames.com) 41

Epic Games, in a blog post: Apple has told us and committed to the European Commission that they will reinstate our developer account. This sends a strong signal to developers that the European Commission will act swiftly to enforce the Digital Markets Act and hold gatekeepers accountable. We are moving forward as planned to launch the Epic Games Store and bring Fortnite back to iOS in Europe. Epic CEO Tim Sweeney adds: The DMA went through its first major challenge with Apple banning Epic Games Sweden from competing with the App Store, and the DMA just had its first major victory. Following a swift inquiry by the European Commission, Apple notified the Commission and Epic that it would relent and restore our access to bring back Fortnite and launch Epic Games Store in Europe under the DMA law.
News

United Plane Veers Off Runway in Third Boeing Incident This Week (bnnbloomberg.ca) 132

A United Airlines Holdings aircraft ran off the taxiway into a grassy area after landing at Houston Friday, the third incident this week involving the airline's Boeing planes. From a report: United Flight 2477, with 160 passengers and six crew, had just landed at George Bush Intercontinental Airport about 8 a.m. local time Friday when it veered into the grass on a turn. No one was injured, and passengers left the plane on a set of stairs before being bused to the terminal, the airline said.

The incident follows the mid-air loss of a tire from a United Boeing 777-200 Thursday, just after the plane took off from San Francisco on a flight to Osaka, Japan, and an engine fire on a United flight from Houston to Fort Myers, Florida, earlier this week. The plane in the Houston-to-Florida flight had to make an emergency landing after one of its engines burst into flames 10 minutes after takeoff. The 21-year-old aircraft was also a 737 -- but an earlier version than the Max, according to FlightRadar24.

United States

Pentagon Review Finds No Evidence of Alien Cover-Up 106

An anonymous reader shares a report: In the 1960s, secret test flights of advanced government spy planes generated U.F.O. sightings. More recently, government and commercial drones, new kinds of satellites and errant weather balloons have led to a renaissance in unusual observations. But, according to a new report, none of these sightings were of alien spacecraft. The new congressionally mandated Pentagon report found no evidence that the government was covering up knowledge of extraterrestrial technology and said there was no evidence that any U.F.O. sightings represented alien visitation to Earth.

The 63-page document is the most sweeping rebuttal the Pentagon has issued in recent years to counter claims that it has information on extraterrestrial visits or technology. But amid widespread distrust of the government, the report is unlikely to calm a growing obsession with aliens. Maj. Gen. Patrick Ryder, a Defense Department spokesman, said the Pentagon approached the report with an open mind and no preconceived notions, but simply found no evidence to back up claims of secret programs, hidden alien technology or anything else extraterrestrial.
The new report suggests that the public's belief that the government is hiding what it knows will probably continue. The report adds: Nevertheless the public is unlikely to be swayed. Many people dismiss the government's claims that nothing interesting is going on in Pentagon videos that appear to show strange objects, citing accounts by Navy pilots that they observed objects whose movements cannot be easily explained. The new report notes that in the past, particularly in the 1950s, there was interest in U.F.O.s, but today the attention on unexplained sightings is greater than ever before. Politico adds: The Pentagon has disclosed that the government once considered a program to recover and reverse-engineer any captured alien spacecraft, an effort that never came to fruition but fueled conspiracy theories about a cover-up.
Businesses

After Astra Loses 99% of Its Value, Founders Take Rocket Firm Private 13

Astra Space, a California-based rocket company, has announced it will go private at a valuation significantly lower than its $2.1 billion debut in 2021. The company's market value is about $13 million at current levels. The company's co-founders, Chris Kemp and Adam London, will acquire all outstanding shares at $0.50 each, well below the current trading price of $0.80. Astra has faced challenges, with only two successful launches out of seven attempts of its Rocket 3 vehicle. The company pivoted to the larger Rocket 4 in 2022 but has yet to conduct test launches.

Astra faces competition from established players like Rocket Lab and Firefly, as well as new entrants such as ABL Space and Stoke Space. The company's future remains uncertain as it navigates a competitive small launch market, with SpaceX's Transporter missions offering lower prices by launching dozens of satellites simultaneously on its Falcon 9 booster.
Microsoft

Microsoft Says Russian Hackers Stole Source Code After Spying On Its Executives (theverge.com) 29

Microsoft revealed earlier this year that Russian state-sponsored hackers had been spying on the email accounts of some members of its senior leadership team. Now, Microsoft is disclosing that the attack, from the same group behind the SolarWinds attack, has also led to some source code being stolen in what Microsoft describes as an ongoing attack. From a report: "In recent weeks, we have seen evidence that Midnight Blizzard [Nobelium] is using information initially exfiltrated from our corporate email systems to gain, or attempt to gain, unauthorized access," explains Microsoft in a blog post. "This has included access to some of the company's source code repositories and internal systems. To date we have found no evidence that Microsoft-hosted customer-facing systems have been compromised."

It's not clear what source code was accessed, but Microsoft warns that the Nobelium group, or "Midnight Blizzard," as Microsoft refers to them, is now attempting to use "secrets of different types it has found" to try to further breach the software giant and potentially its customers. "Some of these secrets were shared between customers and Microsoft in email, and as we discover them in our exfiltrated email, we have been and are reaching out to these customers to assist them in taking mitigating measures," says Microsoft.

AI

President Biden Calls for Ban on AI Voice Impersonations (variety.com) 145

President Biden included a nod to a rising issue in the entertainment and tech industries during his State of the Union address Thursday evening, calling for a ban on AI voice impersonations. From a report: "Here at home, I have signed over 400 bipartisan bills. There's more to pass my unity agenda," President Biden said, beginning to list off a series of different proposals that he hopes to address if elected to a second term. "Strengthen penalties on fentanyl trafficking, pass bipartisan privacy legislation to protect our children online, harness the promise of AI to protect us from peril, ban AI voice impersonations and more."

The president did not elaborate on the types of guardrails or penalties that he would plan to institute around the rising technology, or if it would extend to the entertainment industry. AI was a peak concern for SAG-AFTRA during the actors union's negotiations with and strike against the major studios last year.

China

China Readies $27 Billion Chip Fund To Counter Growing US Curbs (bloomberg.com) 13

China is in the process of raising more than $27 billion for its largest chip fund to date, accelerating the development of cutting-edge technologies to counter a US campaign to thwart its rise. From a report: The National Integrated Circuit Industry Investment Fund is amassing a pool of capital from local governments and state enterprises for its third vehicle that should exceed the 200 billion yuan of its second fund, according to people familiar with the matter. Known as the Big Fund, the state-backed firm is expanding its remit just as the US prepares to sharply escalate technology curbs designed to curtail Chinese chip and artificial intelligence progress.

The establishment of a much larger third fund -- directly overseen by China's powerful tech ministry -- signals a resurgent effort to harness the world's largest semiconductor market after years of mixed success with central stewardship. Huawei and its partner Semiconductor Manufacturing International Corp. still had to rely on US-origin technology to build an advanced processor last year.

News

10 Years On, Is the World Any Closer To Finding MH370? (cnn.com) 90

An anonymous reader shares a report: For the past 10 years it has remained one of the modern era's greatest mysteries. A commercial airliner with a strong safety record carrying 239 people vanishing from the map, spawning a wide variety of competing theories, books and documentaries and leaving the families of those left behind asking themselves every March 8 -- what happened to those aboard Malaysia Airlines flight 370?

In an era when black boxes have been successfully hauled up from the very depths of the ocean and whole chunks of a downed airliner painstakingly pieced back together to determine what caused a catastrophe, the fate of MH370 remains infuriatingly elusive. It is a plane crash without a plane. A disaster without conclusive proof of what happened to its victims. A story that anyone who embarks on a commercial flight can instantly relate to but one that, for now at least, doesn't have a closing chapter.

[...] This week, many loved ones of those missing returned to Malaysia to urge local authorities to relaunch a search ahead of Friday's anniversary. [...] Aviation experts tell CNN that improved detection technology will likely bring families closer to the missing plane than they ever have been, if a search were to be relaunched. But that will not be cheap. Hundreds of millions of dollars were spent scouring more than 710,000 square kilometers of the Indian Ocean until 2018, but nothing transpired that moved our understanding on from that already available since the very early days.

Operating Systems

Apple Releases visionOS 1.1 With Improvements To Persona, EyeSight, Virtual Keyboard and More (macrumors.com) 26

An anonymous reader quotes a report from MacRumors: Apple today released visionOS 1.1, marking the first major update to the visionOS operating system that was launched alongside the Vision Pro in February. visionOS updates can be installed by going to the Settings app on the Vision Pro, selecting the General section, and choosing Software Update. The Vision Pro headset will need to be removed to install new software, with a progress bar available on the front EyeSight display.

Apple is making several improvements to the Vision Pro with the visionOS update. Mobile Device Management is available for businesses, and Persona and EyeSight look better than before. The virtual keyboard has been updated to address bugs and make cursor positioning more accurate, and there are also bug fixes for the Mac Virtual Display.
Here's a summary of visionOS 1.1 from the release notes: "This update introduces MDM features that enable deployment, device configuration, and management for enterprises. This release also includes Persona improvements, the ability to delete system apps from the Home View, as well as other features, bug fixes, and security updates for your Apple Vision Pro."
The Courts

Should an Emoji Count As Confirmation of a Contract? (www.cbc.ca) 89

innocent_white_lamb shares a report from CBC News: In June, a Court of King's Bench judge ordered Swift Current farmer Chris Achter to pay more than $82,000 to a grain buyer with South West Terminal (SWT). The ruling stems from a text message when the buyer, Kent Mickleborough, asked Achter to confirm a flax contract that requested more than 85 tons of flax to be delivered in the fall at about $670 per ton. Achter responded with a thumbs-up emoji. The case hinges on whether the emoji confirmed the contract, or only confirmed receipt of it -- and whether an emoji can ever be used as a signature.

In his June decision ruling in SWT's favor, Justice Timothy Keene wrote, "This court readily acknowledges that a [thumbs-up] emoji is a non-traditional means to 'sign' a document but nevertheless under these circumstances this was a valid way to convey the two purposes of a 'signature.'" Achter is now appealing that ruling.

"Our position is that the emoji cannot be a signature, basically because it does not convey the intention to be bound by an agreement the same as a normal signature would," said Jean-Pierre Jordaan, counsel for the defendant, in court on Tuesday. The counsel for SWT disputed that. "Can a text message chain, with a clear offer and -- in our submissions -- a clear acceptance by thumbs up emoji, constitute a note or memorandum signed by the party to be charged, pursuant to section six of the Sale of Goods Act?" counsel posed. "Our answer to that question is yes; there is no magic in a signature." The three appeal judges reserved their decision for an undetermined date.

Biotech

Mexico Argues Glyphosate In GM Corn Is Unsafe For Human Consumption (reuters.com) 106

Mexico is waiting for the United States to provide evidence that shows imported genetically modified corn is safe for human consumption. "In a written submission to a panel of the United States-Mexico-Canada Agreement, Mexico, the top buyer of U.S. corn, argued that science proves GM corn and the herbicide glyphosate are harmful to human health and its native varieties, and that its decree to ban GM corn for human consumption is within its right," reports Reuters. From the report: [Deputy Agriculture Secretary Victor Suarez] said the onus is now on the United States to show GM corn is not harming Mexico's population, which consumes a higher amount of corn than many countries through daily diet staples like nixtamalized dough and tortilla. The United States "argues that the decisions in Mexico are not based on science and that their decisions are," Suarez told Reuters in an interview. "But we still haven't seen the science of the United States or the companies. We are looking forward to that study with great pleasure."

A spokesman for the U.S. Department of Agriculture said Mexico's approach to biotechnology runs counter to "decades' worth of evidence demonstrating its safety." A senior official for the U.S. Trade Representative said, "Scientific authorities, including in Mexico, have consistently found biotech products like corn to be safe over a period of decades." [...] Mexico's written response cited studies it said showed links between GM corn consumption and glyphosate exposure to liver inflammation in people and impacts to immune response in animals, saying it considers the risk to human health "extremely serious."

The United States in August requested a dispute settlement panel under the USMCA over Mexico's decree to ban GM corn for human consumption, specifically in the use of making flour for tortillas. The decree allows the use of GM yellow corn in animal feed, which accounts for the majority of Mexico's nearly $5.9 billion worth of U.S. corn imports annually. Washington argues Mexico's decree banning imports of GM corn used for tortillas is not based on science and violates its commitments under the USMCA, which has been in place since 2020. "There is no impact on trade," Suarez said of Mexico's decree. "The value and volume of exports of GM corn to Mexico has increased."

Mexico's decree also calls for the gradual substitution of GM corn, a point of contention highlighted by U.S. officials. In its written response, Mexico argued that no specific time frame has been established and therefore it has had no trade impact. "It is a strategic goal, like the United States would like to have energy sovereignty and energy self-sufficiency," Suarez said. The United States is expected to issue a rebuttal to Mexico's response.

Medicine

Microscopic Plastics Could Raise Risk of Stroke and Heart Attack, Study Says 57

An anonymous reader quotes a report from The Guardian: Doctors have warned of potentially life-threatening effects from plastic pollution after finding a substantially raised risk of stroke, heart attack and earlier death in people whose blood vessels were contaminated with microscopic plastics. Researchers in Naples examined fatty plaques removed from the blood vessels of patients with arterial disease and found that more than half had deposits contaminated with tiny particles of polyethylene or polyvinyl chloride (PVC). Those whose plaques contained microplastics or nanoplastics were nearly five times more likely to suffer a stroke, heart attack or death from any cause over the following 34 months, compared with those whose plaques were free from plastic contamination. The findings do not prove that plastic particles drive strokes and heart attacks -- people who are more exposed to the pollution may be at greater risk for other reasons -- but research on animals and human cells suggests the particles may be to blame. [...]

Writing in the New England Journal of Medicine, the doctors describe how they analyzed fatty plaques removed from 304 patients with atherosclerosis affecting the carotid arteries. The carotid arteries are the main blood vessels that supply blood to the neck, face and brain. The disease causes a build-up of plaque in the arteries, which substantially raises the risk of stroke. The plaques can be removed by a procedure called carotid endarterectomy. Lab tests on the extracted plaques revealed polyethylene in 150 patients and polyvinyl chloride in 31, alongside signs of inflammation. On examination under an electron microscope, the researchers spotted jagged foreign particles in the fatty deposits, most less than a thousandth of a millimeter across. The doctors followed 257 of the patients for an average of 34 months after they had carotid plaques removed. Those who had plastic particles in their plaques were 4.5 times more likely to have a stroke or heart attack, or to die from any cause, than those whose plaques were free from plastic pollution.
"People must become aware of the risks we are taking with our lifestyle," said Dr Raffaele Marfella, first author on the study at the University of Campania Luigi Vanvitelli in Naples. "I hope the alarm message from our study will raise the consciousness of citizens, especially governments, to finally become aware of the importance of the health of our planet. To put it in a slogan that can unite the need for health for humans and the planet, plastic-free is healthy for the heart and the Earth."
Science

Company That Plans To Bring Back the Mammoth Takes a Key Step (arstechnica.com) 29

John Timmer reports via Ars Technica: A company called Colossal plans to pioneer the de-extinction business, taking species that have died within the past few thousand years and restoring them through the use of DNA editing and stem cells. It's grabbed headlines recently by announcing some compelling targets: the thylacine, an extinct marsupial predator, and an icon of human carelessness, the dodo. But the company was formed to tackle an even more audacious target: the mammoth, which hasn't roamed the Northern Hemisphere for thousands of years. Obviously, there are a host of ethical and conservation issues that would need to be worked out before Colossal's plans go forward. But there are some major practical hurdles as well, most of them the product of the distinct and extremely slow reproductive biology of the mammoth's closest living relatives, the elephants. At least one of those has now been cleared, as the company is announcing the production of the first elephant stem cells. The process turned out to be extremely difficult, suggesting that the company still has a long road ahead of it. [...] Overall, it's a project that has a high probability of failure and may ultimately require generations of scientists. If we do successfully de-extinct a species, the first example will probably be a different species, even though the projects launched later.

But Colossal is forging ahead and cleared one of the many hurdles it faces: It created the first induced stem cells from elephants and will be placing a draft manuscript describing the process on a public repository on Wednesday. (Colossal provided Ars with an advanced version of the draft that, outside of a few editing errors, appears largely complete.) Beyond providing the technical details of how the process works, the manuscript describes a long, failure-ridden route to eventual success. Several methods have been developed to allow us to induce stem cells from the cells of an adult organism. The original Nobel-winning process developed by Shinya Yamanaka involved inserting the genes that encode four key embryonic regulatory genes into adult cells and allowing them to reprogram the adult cell into an embryonic state. That has proven effective in a variety of species but has a couple of drawbacks due to the fact that the four genes can potentially stick around, interfering with later development steps. Although there are ways around that, others have developed a cocktail of chemicals that perform a similar function by activating signaling pathways that, collectively, can also reprogram adult cells. When it works, this simplifies matters, as you only have to remove the chemicals to allow the stem cells to adopt other fates. Colossal tried both of these. Neither worked with elephant cells: "Multiple attempts with current standard reprogramming methods were tried, and failed, and resulted in no, or incomplete, reprogramming." Apparently, lots of additional trial and error ensued. The eventual solution ended up being based in part on combining the two primary options: Cells were first exposed to a chemical reprogramming cocktail and then given the four genes used in the alternative reprogramming method. On its own, however, that wasn't enough. The researchers also had to address a quirk of elephant biology.

Obviously, for Colossal, this is a means to an end: the mammoth. But that's remarkably underplayed in the manuscript. Instead, its emphasis is on the technology's use in the conservation of existing species. [T]he researchers note that studying things like elephant development and metabolism in actual elephants is not especially realistic. But we can potentially induce the stem cells developed here into any cell we'd want to study -- nerve, liver, heart, and so on. So, the stem cells described here could be a useful tool for research. So, these cells are being presented as a valuable tool for the research community. Still, you can expect the people behind the de-extinction project to be getting to work on some of the easier things: showing that the genome in the cells can be edited and that they can be induced to start the process of embryogenesis. Separately, some unfortunate individuals will need to be working on the hard problems we mentioned earlier.

AI

Reddit Will Now Use an AI Model To Fight Harassment (androidauthority.com) 75

An APK teardown performed by Android Authority has revealed that Reddit is now using a Large Language Model (LLM) to detect harassment on the platform. From the report: Reddit also updated its support page a week ago to mention the use of an AI model as part of its harassment filter. "The filter is powered by a Large Language Model (LLM) that's trained on moderator actions and content removed by Reddit's internal tools and enforcement teams," reads an excerpt from the page. The Register reports: The filter can be enabled in a Reddit community's mod tools, but individual moderators will need to have permissions to change subreddit settings to enable it. The harassment filter can be set to low ("filters the least content but with the most accurate results") and high ("filters the most content but may be less accurate"), and also includes an explicit allow list to force the AI to ignore certain keywords, up to 15 of which can be added. Once enabled, the filter creates a new tag in the moderation queue called "potential harassment," which moderators can review for accuracy. Reddit's help page says the feature is now available on desktop and the official Reddit apps, though it's not clear when the feature was added.

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