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Biotech

Biotech Wizard Left a Trail of Fraud -- Prosecutors Allege It Ended in Murder (wsj.com) 25

Serhat Gumrukcu faces trial in a purported plot to kill an associate who could have exposed him and derailed a drug-development deal worth millions. From a report: Even as a teenager back in Turkey, Serhat Gumrukcu dazzled audiences. In a 2002 video, he opened one of his magic shows dancing with a cane that appeared to be levitating. He was introduced as a medical student and went by the stage name "Dr. No." A little more than a decade later, not long after Mr. Gumrukcu arrived in the U.S., he had his hand in multimillion-dollar oil and real-estate deals. Yet his best-known venture was in medicine. For a time, he thrilled investors with ideas for groundbreaking treatments and drew special notice from the government's top infectious-disease official, Anthony Fauci. In America, the magician had found a new, more lucrative audience.

Enochian Biosciences co-founded by Mr. Gumrukcu in 2018, paid more than $21 million to companies controlled by Mr. Gumrukcu and his husband for consulting, research and the licensing of potential drugs to treat influenza, hepatitis B, HIV and Covid-19, company financial filings show. "Dr. Gumrukcu is one of those rare geniuses that is not bound by scientific discipline or dogma. He sees connections and opportunities often missed," Enochian Vice Chairman Mark Dybul, now chief executive, said in a 2019 news release about Enochian's licensing of a hepatitis B drug from a company controlled by Mr. Gumrukcu. Mr. Gumrukcu's success as a biotech entrepreneur afforded the purchase last year of an $18.4 million office complex in North Hollywood, a neighborhood in Los Angeles, and, earlier, a $5.5 million house in the Hollywood Hills.

Yet much of what people saw in Mr. Gumrukcu was an illusion he cast, misrepresenting himself and his credentials, according to state and federal authorities, court records, former colleagues and those who have sued and won judgments against him over fraudulent medical and financial dealings. Prosecutors now allege that Mr. Gumrukcu arranged the murder of a business associate, Gregory Davis, who threatened to expose him as a fraud. Such a revelation would have put at risk the 39-year-old entrepreneur's deal with Enochian, they said. Mr. Gumrukcu has been in custody at the Metropolitan Detention Center in Los Angeles since his arrest on May 24. A federal grand jury indicted him on murder conspiracy charges, an offense punishable by death.

Robotics

Brain-Machine Interface Helps Man With Paralysis Feed Himself Using Robotic Arms (engadget.com) 13

An anonymous reader quotes a report from Engadget: Johns Hopkins University-led researchers have developed a new technique that let a partially paralyzed man feed himself using robotic arms connected through a brain-machine interface. He only had to make small movements with his fists at certain prompts (such as "select cut location") to have the fork- and knife-equipped arms cut food and bring it to his mouth. He could have dessert within 90 seconds, according to the researchers. The new method centers on a shared control system that minimizes the amount of mental input required to complete a task. He could map his four-degree freedom of movement (two for each hand) to as many as 12 degrees of freedom for controlling the robot arms. The limbs' prompt-based intelligent responses also reduced the workload. The researchers "want to add touch-like sensor feedback instead of relying exclusively on visuals," the report says. "They also hope to improve the accuracy and efficiency while reducing the need for visual confirmation."
Earth

New Study Solves Long-Standing Mystery of What May Have Triggered Ice Age 101

nickwinlund77 shares a report from Phys.Org: A new study led by University of Arizona researchers may have solved two mysteries that have long puzzled paleo-climate experts: Where did the ice sheets that rang in the last ice age more than 100,000 years ago come from, and how could they grow so quickly? Understanding what drives Earth's glacial -- interglacial cycles -- the periodic advance and retreat of ice sheets in the Northern Hemisphere -- is no easy feat, and researchers have devoted substantial effort to explaining the expansion and shrinking of large ice masses over thousands of years. The new study, published in the journal Nature Geoscience, proposes an explanation for the rapid expansion of the ice sheets that covered much of the Northern Hemisphere during the most recent ice age, and the findings could also apply to other glacial periods throughout Earth's history.

About 100,000 years ago, when mammoths roamed the Earth, the Northern Hemisphere climate plummeted into a deep freeze that allowed massive ice sheets to form. Over a period of about 10,000 years, local mountain glaciers grew and formed large ice sheets covering much of today's Canada, Siberia and northern Europe. While it has been widely accepted that periodic "wobbling" in the Earth's orbit around the sun triggered cooling in the Northern Hemisphere summer that caused the onset of widespread glaciation, scientists have struggled to explain the extensive ice sheets covering much of Scandinavia and northern Europe, where temperatures are much more mild. [...] "Using both climate model simulations and marine sediment analysis, we show that ice forming in northern Canada can obstruct ocean gateways and divert water transport from the Arctic into the North Atlantic," [said Lofverstrom, an assistant professor of geosciences and head of the UArizona Earth System Dynamics Lab], "and that in turn leads to a weakened ocean circulation and cold conditions off the coast of Scandinavia, which is sufficient to start growing ice in that region."

"These findings are supported by marine sediment records from the North Atlantic, which show evidence of glaciers in northern Canada several thousand years before the European side," said Diane Thompson, assistant professor in the UArizona Department of Geosciences. "The sediment records also show compelling evidence of a weakened deep ocean circulation before the glaciers form in Scandinavia, similar to our modeling results." Together, the experiments suggest that the formation of marine ice in northern Canada may be a necessary precursor to glaciation in Scandinavia, the authors write. [...] "It is possible that the mechanisms we identified here apply to every glacial period, not just the most recent one," [Lofverstrom] said. "It may even help explain more short-lived cold periods such as the Younger Dryas cold reversal (12,900 to 11,700 years ago) that punctuated the general warming at the end of the last ice age."
Science

Viruses Survive in Fresh Water by 'Hitchhiking' on Plastic, Study Finds (theguardian.com) 24

Dangerous viruses can remain infectious for up to three days in fresh water by hitchhiking on plastic, researchers have found. From a report: Enteric viruses that cause diarrhoea and stomach upsets, such as rotavirus, were found to survive in water by attaching to microplastics, tiny particles less than 5mm long. They remain infectious, University of Stirling researchers found, posing a potential health risk. Prof Richard Quilliam, lead researcher on the project at Stirling University, said: "We found that viruses can attach to microplastics and that allows them to survive in the water for three days, possibly longer." While previous research had been carried out in sterile settings, this is the first research into how viruses behave in the environment, Quilliam said. However, he used standard laboratory methods to determine whether viruses found on microplastics in water were infectious.

"We weren't sure how well viruses could survive by 'hitchhiking' on plastic in the environment, but they do survive and they do remain infectious," he said. The findings, part of a $2.27m project funded by the Natural Environment Research Council looking at how plastics transport bacteria and viruses, concluded that microplastics enabled pathogen transfer in the environment. The paper is published in the journal Environmental Pollution. "Being infectious in the environment for three days, that's long enough to get from the wastewater treatment works to the public beach," Quilliam said. Wastewater treatment plants were unable to capture microplastics, he said. "Even if a wastewater treatment plant is doing everything it can to clean sewage waste, the water discharged still has microplastics in it, which are then transported down the river, into the estuary and wind up on the beach."

Biotech

Chinese Team Claims Stem Cell Breakthrough in Mice Study (newatlas.com) 62

"Researchers at Tsinghua University in China have developed a new drug cocktail that can convert cells into totipotent stem cells, the very seeds of life..." writes New Atlas: Not all stem cells are created equal — they sit in a branching hierarchy of differentiation potential. Multipotent stem cells are found in many tissues in adults, where they can turn into a few types of cells associated with that tissue or organ to help healing. A step earlier in the development tree are pluripotent stem cells, which are found in embryos and can become almost any type of cell in the body.

But at the top of the chain sit what are known as totipotent stem cells, which can become any cell in the body as well as supportive tissues like the placenta. These mark the very beginning of development, including the first single cell that forms from a fertilized egg, and they persist for the first few stages of development. After that, the cells differentiate into pluripotent stem cells and further specialize into all the cells of the body as it develops.

In recent years scientists have been able to take adult cells and induce a pluripotent state in them, which forms the basis of research into stem cell regenerative medicine. But in the new study, the Tsinghua team took things a step further, returning pluripotent stem cells to a totipotent state for the first time...

This breakthrough could open up some major new opportunities, the team says. In the long run, scientists could potentially create a living organism straight from a mature cell, sidestepping the need for sperm and eggs. That could help people have children who otherwise couldn't, or aid conservation of endangered species.

The researchers do acknowledge, however, that ethical concerns will no doubt arise.

Thanks to long-time Slashdot reader hackingbear for sharing the news.
Space

Satellites are Sinking Faster Toward Earth. Scientists Blame Solar Wind (space.com) 30

"In late 2021, operators of the European Space Agency's Swarm constellation noticed something worrying," reports Space.com. "The satellites, which measure the magnetic field around Earth, started sinking toward the atmosphere at an unusually fast rate — up to 10 times faster than before.

"The change coincided with the onset of the new solar cycle, and experts think it might be the beginning of some difficult years for spacecraft orbiting our planet." "In the last five, six years, the satellites were sinking about two and a half kilometers [1.5 miles] a year," Anja Stromme, ESA's Swarm mission manager, told Space.com. "But since December last year, they have been virtually diving. The sink rate between December and April has been 20 kilometers [12 miles] per year."

Satellites orbiting close to Earth always face the drag of the residual atmosphere, which gradually slows the spacecraft and eventually makes them fall back to the planet. (They usually don't survive this so-called re-entry and burn up in the atmosphere.) This atmospheric drag forces the International Space Station's controllers to perform regular "reboost" maneuvers to maintain the station's orbit of 250 miles (400 km) above Earth. This drag also helps clean up the near-Earth environment from space junk.

Scientists know that the intensity of this drag depends on solar activity — the amount of solar wind spewed by the sun, which varies depending on the 11-year solar cycle.... [S]ince last fall, the star has been waking up, spewing more and more solar wind and generating sunspots, solar flares and coronal mass ejections at a growing rate. And the Earth's upper atmosphere has felt the effects. "There is a lot of complex physics that we still don't fully understand going on in the upper layers of the atmosphere where it interacts with the solar wind," Stromme said. "We know that this interaction causes an upwelling of the atmosphere. That means that the denser air shifts upwards to higher altitudes."

Denser air means higher drag for the satellites. Even though this density is still incredibly low 250 miles above Earth, the increase caused by the upwelling atmosphere is enough to virtually send some of the low-orbiting satellites plummeting. "It's almost like running with the wind against you," Stromme said. "It's harder, it's drag — so it slows the satellites down, and when they slow down, they sink...." The lower the orbit of the satellites when the solar storm hits, the higher the risk of the spacecraft not being able to recover, leaving operators helplessly watching as the craft fall to their demise in the atmosphere....

All spacecraft around the 250-mile altitude are bound to have problems, Stromme said. That includes the International Space Station, which will have to perform more frequent reboost maneuvers to keep afloat, but also the hundreds of cubesats and small satellites that have populated low Earth orbit in the past decade.... "Many of these [new satellites] don't have propulsion systems," Stromme said. "They don't have ways to get up. That basically means that they will have a shorter lifetime in orbit. They will reenter sooner than they would during the solar minimum."

Thanks to long-time Slashdot reader schwit1 for sharing the article!
China

How China Hopes to Fly Mars Samples to Earth Two Years Before NASA and ESA (spacenews.com) 88

"China's Mars sample return mission aims to collect samples from the Red Planet and deliver them to Earth in 2031, or two years ahead of a NASA and ESA joint mission," reports SpaceNews: Lifting off in late 2028... the complex, multi-launch mission will have simpler architecture in comparison with the joint NASA-ESA project, with a single Mars landing and no rovers sampling different sites. However, if successful, it would deliver to Earth the first collected Martian samples; an objective widely noted as one of the major scientific goals of space exploration....

The mission will build on the Mars entry, descent and landing technologies and techniques demonstrated by Tianwen-1 in May 2021, as well as the regolith sampling, automated lunar orbit rendezvous and docking, and high velocity atmospheric reentry success achieved by the 2020 Chang'e-5 lunar sample return mission.... Landing on Mars would take place around September 2029. Sampling techniques will include surface sampling, drilling and mobile intelligent sampling, potentially using a four-legged robot.

The ascent vehicle will consist of two stages, using either solid or liquid propulsion, and will be required to reach a speed of 4.5 kilometers per second, according to the presentation. After rendezvous and docking with the waiting orbiter, the spacecraft will depart Mars orbit in late October 2030 for a return to Earth in July 2031.

Sun Zezhou [chief designer of the Tianwen-1 Mars orbiter and rover mission], added that the Tianwen-1 orbiter will conduct an aerobraking test in Mars orbit later this year as part of the sample return mission preparation.

Thanks to Slashdot reader Hmmmmmm for sharing the story!
Science

Is Dyslexia an Evolutionary Advantage Rather Than a 'Disorder'? (msn.com) 133

LinkedIn recently added 'dyslexic thinking' as an official skill.

And now the U.K. national newspaper the Telegraph reports on scientists arguing that dyslexia is not a "disorder" — but an evolutionarily beneficial willingness to explore: The experts suggested that dyslexia, which causes difficulty reading, writing and spelling, is a useful specialisation and not a "neurocognitive condition"....

About one in five people have dyslexia, and their tendency to push the envelope would have been balanced out by other members of a prehistoric society, leading to a well-rounded group with equally useful skill sets. However, Dr Helen Taylor, from the University of Strathclyde, and Dr Martin Vestergaard, from the University of Cambridge, said that dyslexia was now seen as a problem because modern education systems focused on the things sufferers struggled with and neglected what they excelled at. They reassessed past studies on dyslexic individuals and disagreed with the prevailing theory that it was a cognitive deficit....

[S]ince the invention of written language, dyslexia has been seen as a problem, not a talent. "Schools, academic institutes and workplaces are not designed to make the most of explorative learning," said Dr Taylor. "We urgently need to start nurturing this way of thinking to allow humanity to continue to adapt and solve key challenges." They posit that dyslexic people are naturally more skilled "in realms like discovery, invention and creativity" and that this specialisation stems from millennia of human evolution.... Without the streak of curiosity and willingness to investigate that is commonplace in dyslexic brains, groups of people would likely struggle to survive, they said.

"The deficit-centred view of dyslexia isn't telling the whole story," said Dr Taylor. "We believe that the areas of difficulty experienced by people with dyslexia result from a cognitive trade-off between exploration of new information and exploitation of existing knowledge, with the upside being an explorative bias that could explain enhanced abilities observed in certain realms like discovery, invention and creativity.

The researchers argue this "explorative specialization in people with dyslexia could help explain why they have difficulties with tasks related to exploitation, such as reading and writing.

"It could also explain why people with dyslexia appear to gravitate towards certain professions that require exploration-related abilities, such as arts, architecture, engineering and entrepreneurship."

Thanks to Slashdot reader Bruce66423 for sharing the story
AI

A Single AI-Enhanced Brain Scan Can Diagnose Alzheimer's Disease (imperial.ac.uk) 10

Long-time Slashdot reader schwit1 shares an announcement from London's Imperial College of Science, Technology and Medicine: A single MRI scan of the brain could be enough to diagnose Alzheimer's disease, according to new research by Imperial College London.

The research uses machine learning technology to look at structural features within the brain, including in regions not previously associated with Alzheimer's. The advantage of the technique is its simplicity and the fact that it can identify the disease at an early stage when it can be very difficult to diagnose. Although there is no cure for Alzheimer's disease, getting a diagnosis quickly at an early stage helps patients. It allows them to access help and support, get treatment to manage their symptoms and plan for the future. Being able to accurately identify patients at an early stage of the disease will also help researchers to understand the brain changes that trigger the disease, and support development and trials of new treatments....

The researchers adapted an algorithm developed for use in classifying cancer tumours, and applied it to the brain. They divided the brain into 115 regions and allocated 660 different features, such as size, shape and texture, to assess each region. They then trained the algorithm to identify where changes to these features could accurately predict the existence of Alzheimer's disease... They found that in 98 per cent of cases, the MRI-based machine learning system alone could accurately predict whether the patient had Alzheimer's disease or not. It was also able to distinguish between early and late-stage Alzheimer's with fairly high accuracy, in 79 per cent of patients.

Professor Eric Aboagye, from Imperial's Department of Surgery and Cancer, who led the research, said: "Currently no other simple and widely available methods can predict Alzheimer's disease with this level of accuracy, so our research is an important step forward...." The new system spotted changes in areas of the brain not previously associated with Alzheimer's disease, [which] opens up potential new avenues for research into these areas and their links to Alzheimer's disease.

Professor Aboagye adds that this new approach "could also identify early-stage patients for clinical trials of new drug treatments or lifestyle changes, which is currently very hard to do."
Medicine

Pig Heart Transplant Failure: Doctors Detail Everything That Went Wrong (arstechnica.com) 61

An anonymous reader quotes a report from Ars Technica: Earlier this year, news broke of the first experimental xenotransplantation: A human patient with heart disease received a heart from a pig that had been genetically engineered to avoid rejection. While initially successful, the experiment ended two months later when the transplant failed, leading to the death of the patient. At the time, the team didn't disclose any details regarding what went wrong. But this week saw the publication of a research paper that goes through everything that happened to prepare for the transplant and the weeks following. Critically, this includes the eventual failure of the transplant, which was triggered by the death of many of the muscle cells in the transplanted heart. But the reason for that death isn't clear, and the typical signs of rejection by the immune system weren't present. So, we're going to have to wait a while to understand what went wrong.
[...]
After death, the team performed an autopsy on the transplanted heart. They found that it had nearly doubled in weight, largely because of fluid (and some red blood cells) leaking out of blood vessels in the absence of clotting. There was significant death of heart muscle cells, but that was scattered across the heart, rather than being a general phenomenon. Critically, most of the indications of a strong immune rejection were missing. The presence of an apparent pig cytomegalovirus was worrying, but the researchers indicate there's some question about whether the tests that picked it up might have been recognizing a closely related human virus -- one that's often associated with organ transplant problems.

So, for now, it's not clear what happened with this transplant or what the significance of the apparent viral infection is. Obviously, the team has lots of material to work with to try to figure out what went on, and there's a long, long list of potential experiments to do with it. And there are also additional xenotransplant trials in the works, so it may not be long before we have a better sense of whether this was something specific to this transplant or a general risk of xenotransplantation.

Moon

Rogue Rocket's Moon Crash Site Spotted By NASA Probe (space.com) 16

The grave of a rocket body that slammed into the moon more than three months ago has been found. Space.com reports: Early this year, astronomers determined that a mysterious rocket body was on course to crash into the lunar surface on March 4. Their calculations suggested that the impact would occur inside Hertzsprung Crater, a 354-mile-wide (570 kilometers) feature on the far side of the moon. Their math was on the money, it turns out. Researchers with NASA's Lunar Reconnaissance Orbiter (LRO) mission announced last night (June 23) that the spacecraft had spotted a new crater in Hertzsprung -- almost certainly the resting place of the rogue rocket.

Actually, LRO imagery shows that the impact created two craters, an eastern one about 59 feet (18 meters) wide superimposed over a western one roughly 52 feet (16 m) across. "The double crater was unexpected and may indicate that the rocket body had large masses at each end," Mark Robinson of Arizona State University, the principal investigator of the Lunar Reconnaissance Orbiter Camera (LROC), wrote in an update last night. "Typically a spent rocket has mass concentrated at the motor end; the rest of the rocket stage mainly consists of an empty fuel tank," he added. "Since the origin of the rocket body remains uncertain, the double nature of the crater may help to indicate its identity."

As Robinson noted, the moon-crashing rocket remains mysterious. Early speculation held that it was likely the upper stage of the SpaceX Falcon 9 rocket that launched the Deep Space Climate Observatory (DSCOVR) mission for NASA and the U.S. National Oceanic and Atmospheric Administration in February 2015. But further observations and calculations changed that thinking, leading many scientists to conclude that the rocket body was probably part of the Long March 3 booster that launched China's Chang'e 5T1 mission around the moon in October 2014. China has denied that claim.

Science

Engineers Demonstrate Quantum Integrated Circuit Made Up of Just a Few Atoms (newatlas.com) 21

Engineers in Sydney have demonstrated a quantum integrated circuit made up of just a few atoms. By precisely controlling the quantum states of the atoms, the new processor can simulate the structure and properties of molecules in a way that could unlock new materials and catalysts. New Atlas reports: The new quantum circuit comes from researchers at the University of New South Wales (UNSW) and a start-up company called Silicon Quantum Computing (SQC). It's essentially made up of 10 carbon-based quantum dots embedded in silicon, with six metallic gates that control the flow of electrons through the circuit. It sounds simple enough, but the key lies in the arrangement of these carbon atoms down to the sub-nanometer scale. Relative to each other, they're precisely positioned to mimic the atomic structure of a particular molecule, allowing scientists to simulate and study the structure and energy states of that molecule more accurately than ever before.

In this case, they arranged the carbon atoms into the shape of the organic compound polyacetylene, which is made up of a repeating chain of carbon and hydrogen atoms with an alternating pattern of single and double carbon bonds between them. To simulate those bonds, the team placed the carbon atoms at different distances apart. Next, the researchers ran an electrical current through the circuit to check whether it would match the signature of a natural polyacetylene molecule -- and sure enough, it did. In other tests, the team created two different versions of the chain by cutting bonds at different places, and the resulting currents matched theoretical predictions perfectly. The significance of this new quantum circuit, the team says, is that it could be used to study more complicated molecules, which could eventually yield new materials, pharmaceuticals, or catalysts. This 10-atom version is right on the limit of what classical computers can simulate, so the team's plans for a 20-atom quantum circuit would allow for simulation of more complex molecules for the first time.
The research has been published in the journal Nature.
Windows

The Mars Express Spacecraft Is Finally Getting a Windows 98 Upgrade (theverge.com) 40

Engineers at the European Space Agency (ESA) are getting ready for a Windows 98 upgrade on an orbiter circling Mars. The Verge reports: The Mars Express spacecraft has been operating for more than 19 years, and the Mars Advanced Radar for Subsurface and Ionospheric Sounding (MARSIS) instrument onboard has been using software built using Windows 98. Thankfully for humanity and the Red Planet's sake, the ESA isn't upgrading its systems to Windows ME. The MARSIS instrument on ESA's Mars Express was key to the discovery of a huge underground aquifer of liquid water on the Red Planet in 2018. This major new software upgrade "will allow it to see beneath the surfaces of Mars and its moon Phobos in more detail than ever before," according to the ESA. The agency originally launched the Mars Express into space in 2003 as its first mission to the Red Planet, and it has spent nearly two decades exploring the planet's surface.

MARSIS uses low-frequency radio waves that bounce off the surface of Mars to search for water and study the Red Planet's atmosphere. The instrument's 130-foot antenna is capable of searching around three miles below the surface of Mars, and the software upgrades will enhance the signal reception and onboard data processing to improve the quality of data that's sent back to Earth. "We faced a number of challenges to improve the performance of MARSIS," explains Carlo Nenna, a software engineer at Enginium who is helping ESA with the upgrade. "Not least because the MARSIS software was originally designed over 20 years ago, using a development environment based on Microsoft Windows 98!"

Science

The Sleep Debt Collector Is Here (nytimes.com) 41

Recent studies in humans and mice have shown that late nights and early mornings may cause long lasting damage to your brain. From a report: The sleep debt collectors are coming. They want you to know that there is no such thing as forgiveness, only a shifting expectation of how and when you're going to pay them back. You think of them as you lie in bed at night. How much will they ask for? Are you solvent? You fall asleep, then wake up in a cold sweat an hour later. You fall asleep, then wake up, drifting in and out of consciousness until morning. As most every human has discovered, a couple nights of bad sleep is often followed by grogginess, difficulty concentrating, irritability, mood swings and sleepiness.

For years, it was thought that these effects, accompanied by cognitive impairments like lousy performances on short-term memory tests, could be primarily attributed to a chemical called adenosine, a neurotransmitter that inhibits electrical impulses in the brain. Spikes of adenosine had been consistently observed in sleep-deprived rats and humans. Adenosine levels can be quickly righted after a few nights of good sleep, however. This gave rise to a scientific consensus that sleep debt could be forgiven with a couple of quality snoozes -- as reflected in casual statements like "I'll catch up on sleep" or "I'll be more awake tomorrow."

But a review article published recently in the journal Trends in Neurosciences contends that the folk concept of sleep as something that can be saved up and paid off is bunk. The review, which canvassed the last couple of decades of research on long term neural effects of sleep deprivation in both animals and humans, points to mounting evidence that getting too little sleep most likely leads to long-lasting brain damage and increased risk of neurodegenerative disorders like Alzheimer's disease. "This is really, really important in setting the stage for what needs to be done in sleep health and sleep science," said Mary Ellen Wells, a sleep scientist at the University of North Carolina, who did not contribute to the review.

Science

Female Scientists Less Likely To Be Given Authorship Credits, Analysis Finds (theguardian.com) 85

Female scientists are less likely to receive authorship credit or to be named on patents related to the work they do compared with their male counterparts -- including in fields such as healthcare, where women dominate -- data suggests. From a report: This gender gap may help to explain well-documented disparities in the apparent contributions of male and female scientists -- such as that of Rosalind Franklin, whose pivotal contribution to the discovery of the structure of DNA initially went unrecognised because she was not cited on the core Nature article by James Watson and Francis Crick.

"We have known for a long time that women publish and patent at a lower rate than men. But, because previous data never showed who participated in research, no one knew why," said Prof Julia Lane at New York University in the US, who led the new research. Lane and her colleagues analysed administrative data on research projects conducted at 52 US colleges and universities between 2013 and 2016. They matched information about 128,859 scientists to 39,426 journal articles and 7,675 patents, looking at which people who worked on individual projects received credit and which did not.

Space

Five Planets Take Center Stage as They Align in the Night Sky (cnn.com) 31

A rare, five-planet alignment will peak on June 24, allowing a spectacular viewing of Mercury, Venus, Mars, Jupiter and Saturn as they line up in planetary order. From a report: The event began at the beginning of June and has continued to get brighter and easier to see as the month has progressed, according to Diana Hannikainen, observing editor of Sky & Telescope. A waning crescent moon will be joining the party between Venus and Mars on Friday, adding another celestial object to the lineup. The moon will represent the Earth's relative position in the alignment, meaning this is where our planet will appear in the planetary order. This rare phenomenon has not occurred since December 2004, and this year, the distance between Mercury and Saturn will be smaller, according to Sky & Telescope.
NASA

NASA Declares Megarocket Rehearsal Complete, Setting Stage For Inaugural Launch (gizmodo.com) 44

The fourth and most recent attempt at a full launch rehearsal of NASA's Space Launch System went reasonably well, and despite some lingering issues and uncertainties, the agency is sending the rocket back to the hangar for final preparations in advance of its first flight. That inaugural launch will represent Artemis 1, the first mission in NASA's Artemis lunar program. Gizmodo reports: In a press release today, NASA -- to my surprise -- said it is done testing SLS after reviewing data from the recent launch rehearsal. That another full-blown rehearsal would be required seemed likely to me on account of an unresolved hydrogen leak linked to a faulty quick-connect fitting, which subsequently prevented ground teams from practicing the fully scheduled launch countdown on Monday. The goal was to reach T-10 seconds, but the launch controllers decided to quit the rehearsal at T-29 seconds for safety reasons. "NASA plans to return SLS and Orion to the pad for launch in late August," says the release. "NASA will set a specific target launch date after replacing hardware associated with the leak."

Despite the hydrogen leak and the incomplete countdown, Monday's wet dress did appear to go well. The ground teams finally managed to fully load SLS with propellants. Upwards of 755,000 gallons of cryogenic liquid oxygen and liquid hydrogen were supplied to the rocket's two stages, which the teams had failed to do during the first three attempts. What's more, all of the issues experienced during the first three wet dress rehearsals appear to have been resolved. The Orion spacecraft, currently sitting atop the rocket, also performed well during the test. Said Tom Whitmeyer, NASA's exploration systems manager, during a media teleconference on Tuesday: "We think that we had a really successful rehearsal," adding that there is "relative risk" is running a fifth wet dress, with the 322-foot-tall (98-meter) rocket standing fully exposed on the launch pad.

Science

Government Scientists Discover Biggest Bacteria Ever, Visible To Naked Eye (vice.com) 26

An anonymous reader quotes a report from Motherboard: Scientists have discovered a bacteria with cells that measure a full centimeter in length, an astonishing size that makes it by far the largest bacterial species ever found and even "challenges our concept of a bacterial cell," reports a new study. Bacteria are an extraordinarily diverse group of organisms that have inhabited Earth for billions of years and have evolved to occupy a dizzying variety of niches. Still, almost all of these microbes are composed of simple cells that measure about two microns in diameter, which is about 40 times smaller than a strand of human hair.

Thiomargarita magnifica, a bacteria discovered on sunken red mangrove leaves in Guadeloupe, Lesser Antilles, has blown this standard scale out of the water. The species has evolved filamentary cells that are "larger than all other known giant bacteria by ~50-fold," making them "visible to the naked eye," according to a study published on Thursday in Science. Scientists led by Jean-Marie Volland, a marine biologist who holds joint appointments at the Laboratory for Research in Complex Systems and the Joint Genome Institute (JGI), a U.S. Department of Energy office at Lawrence Berkeley National Laboratory, suspect that this record-breaking adaptation is partly due to the astonishing number of duplicated genes wielded by T. magnifica, an ability that is known as polyploidy. [...]

The results revealed that these bacteria contain DNA clusters in their cells, which are located in compartments bordered by membranes that the team called "pepins." These organized pepins provide a stark contrast to the free-floating DNA seen in the cells of most bacteria. In addition, the team's genetic sequencing revealed that T. magnifica contains hundreds of thousands of genome copies that are dispersed across the cell, adding up to about three times the number of genes in most bacteria, which is an extreme example of polyploidy. "These cellular features likely allow the organism to grow to an unusually large size and circumvent some of the biophysical and bioenergetic limitations on growth," Volland and his colleagues said.

Earth

Scientists Unveil Bionic Robo-fish To Remove Microplastics From Seas (theguardian.com) 21

Scientists have designed a tiny robot-fish that is programmed to remove microplastics from seas and oceans by swimming around and adsorbing them on its soft, flexible, self-healing body. From a report: Microplastics are the billions of tiny plastic particles which fragment from the bigger plastic things used every day such as water bottles, car tyres and synthetic T-shirts. They are one of the 21st century's biggest environmental problems because once they are dispersed into the environment through the breakdown of larger plastics they are very hard to get rid of, making their way into drinking water, produce, and food, harming the environment and animal and human health.

"It is of great significance to develop a robot to accurately collect and sample detrimental microplastic pollutants from the aquatic environment," said Yuyan Wang, a researcher at the Polymer Research Institute of Sichuan University and one of the lead authors on the study. Her team's novel invention is described in a research paper in the journal Nano Letters. "To the best of our knowledge, this is the first example of such soft robots." Researchers at Sichuan University have revealed an innovative solution to track down these pollutants when it comes to water contamination: designing a tiny self-propelled robo-fish that can swim around, latch on to free-floating microplastics, and fix itself if it gets cut or damaged while on its expedition.

China

Extreme Weather Hits China With Massive Floods and Scorching Heat (nytimes.com) 73

China is grappling with extreme weather emergencies across the country, with the worst flooding in decades submerging houses and cars in the south and record-high heat waves in the northern and central provinces causing roads to buckle. From a report: Water levels in more than a hundred rivers across the country have surged beyond flood warning levels, according to the People's Daily, the ruling Communist Party's mouthpiece. The authorities in Guangdong Province on Tuesday raised alerts to the highest level after days of rainfall and floods, closing schools, businesses and public transport in affected areas. The flooding has disrupted the lives of almost half a million people in southern China. Footage on state media showed rescue crews on boats paddling across waterlogged roads to relieve trapped residents. In Shaoguan, a manufacturing hub, factories were ordered to halt production, as water levels have reached a 50-year high, state television reported. Guangdong's emergency management department said that the rainfall has affected 479,600 people, ruined nearly 30 hectares of crops and caused the collapse of more than 1,700 houses, with financial losses totaling $261 million, the official Xinhua News Agency reported.

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