The European Space Agency (ESA) plans to launch a satellite into Earth's orbit in 2027 to watch it get wrecked as it reenters the atmosphere. From a report: The project is intended to help understand how exactly satellites break apart so that scientists can learn how to prevent the creation of more space debris. Space junk is becoming a bigger problem as we send more satellites into orbit, but there are efforts to try and address it. This mission is part of the ESA's Zero Debris Charter initiative to stop the creation of additional space debris by 2030. The mission is called the Destructive Reentry Assessment Container Object (DRACO), and the insides of the satellite will collect data as the craft gets destroyed during reentry into the atmosphere. It will also contain a 40-centimeter capsule designed to survive the destruction that will transmit the collected data as the capsule moves toward the ocean.

An anonymous reader quotes a report from 404 Media: After a horseback riding accident left him paralyzed from the waist down in 2009, former jockey Michael Straight learned to walk again with the help of a $100,000 ReWalk Personal exoskeleton. Earlier this month, that exoskeleton broke because of a malfunctioning piece of wiring in an accompanying watch that makes the exoskeleton work. The manufacturer refused to fix it, saying the machine was now too old to be serviced, and Straight once again couldn't walk anymore. "After 371,091 steps my exoskeleton is being retired after 10 years of unbelievable physical therapy," Straight posted on Facebook on September 16. "The reasons [sic] why it has stopped is a pathetic excuse for a bad company to try and make more money. The reason it stopped is because of a battery in the watch I wear to operate the machine. I called thinking it was no big deal, yet I was told they stopped working on any machine that was 5 years or older. I find it very hard to believe after paying nearly $100,000 for the machine and training that a $20 battery for the watch is the reason I can't walk anymore?"

Straight's experience is a nightmare scenario that highlights what happens when companies decide to stop supporting their products and do not actively support independent repair. It's also what happens without the protection of right to repair legislation that requires manufacturers to make repair parts, guides, and tools available to the general public. Specifically, a connection wire became desoldered from the battery in a watch that connects to the exoskeleton: "It's not the actual battery, but it's the little green connection piece we need to be the right fit and that's been our problem," Straight posted on Facebook. Straight's personal exoskeleton was broken for two months, he said in a video on Facebook. He was eventually able to get the device fixed after attention from an article in the Paulick Report, a website about the horse industry, and a spot on local TV. "It took me two months, and I got no results," he said in the video. With social media and news attention, "it only took you all four days, and look at the results," he said earlier this week while standing in the exoskeleton. "This is the dystopian nightmare that we've kind of entered in, where the manufacturer perspective on products is that their responsibility completely ends when it hands it over to a customer. That's not good enough for a device like this, but it's also the same thing we see up and down with every single product," Nathan Proctor, head of citizen rights group US PIRG's right to repair project told 404 Media. "People need to be able to fix things, there needs to be a plan in place. A $100,000 product you can only use as long as the battery lasts, that's enraging. We should not have to tolerate a society where this happens."

"We have all this technology we release into the wild and it changes people's lives, but there's no long-term thinking. Manufacturers currently have no legal obligation to support the equipment indefinitely and there's no requirements that they publish sufficient documentation to allow others to do it," Proctor said. "We need to set minimum standards for documentation so that, even if a company goes bankrupt or falls off the face of the earth, a technician with sufficient knowledge can fix it."

An anonymous reader shares a report: In the decade-long fight to control CRISPR, the super-tool for modifying DNA, it's been common for lawyers to try to overturn patents held by competitors by pointing out errors or inconsistencies. But now, in a surprise twist, the team that earned the Nobel Prize in chemistry for developing CRISPR is asking to cancel two of their own seminal patents, MIT Technology Review has learned.

The decision could affect who gets to collect the lucrative licensing fees on using the technology. The request to withdraw the pair of European patents, by lawyers for Nobelists Emmanuelle Charpentier and Jennifer Doudna, comes after a damaging August opinion from a European technical appeals board, which ruled that the duo's earliest patent filing didn't explain CRISPR well enough for other scientists to use it and doesn't count as a proper invention. The Nobel laureates' lawyers say the decision is so wrong and unfair that they have no choice but to preemptively cancel their patents, a scorched-earth tactic whose aim is to prevent the unfavorable legal finding from being recorded as the reason.

"The New York Times reports that astronomers have discovered a black hole spitting energy across 23 million light-years of intergalactic space (source paywalled; alternative source)," writes longtime Slashdot reader fahrbot-bot. From the report: Two jets, shooting in opposite directions, compose the biggest lightning bolt ever seen in the sky -- about 140 times as long as our own Milky Way galaxy is wide, and more than 10 times the distance from Earth to Andromeda, the nearest large spiral galaxy. Follow-up observations with optical telescopes traced the eruption to a galaxy 7.5 billion light-years away that existed when the universe was less than half its current age of 14 billion years. At the heart of that galaxy was a black hole spewing energy equivalent to the output of more than a trillion stars.

"The Milky Way would be a little dot in these two giant eruptions," said Martijn Oei, a postdoctoral researcher at the California Institute of Technology. Dr. Oei led the team that made the discovery, which was reported in Nature on Sept. 18 and announced on the journal's cover with an illustration reminiscent of a "Star Wars" poster. The astronomers have named the black hole Porphyrion, after a giant in Greek mythology -- a son of Gaia -- who fought the gods and lost. The discovery raises new questions of how such black holes could affect the evolution and structure of the universe.

New research suggests that Mars' missing atmosphere may have been absorbed by minerals in the planet's clays, in a process similar to geological reactions on Earth. It may explain Mars' loss of its atmosphere and potential to support life, with methane possibly still present and usable as an energy source. Longtime Slashdot reader Baron_Yam writes: Conditions on early Mars were highly likely to have had CO2 carried down into the ground by water, where reactions with rock resulted in iron oxide (and Mars' rust-red surface) and released hydrogen, which in turn reacted with the water to form methane that was bound in smectite clays. It's all still there, just under the surface. The research has been published in the journal Science Advances.

Scientists have proposed a method to deflect dangerous asteroids using nuclear explosions, not by directly blowing them up, but by detonating a bomb above the surface to create an X-ray burst that vaporizes part of the asteroid and changes its course. Experiments using the Z machine at Sandia National Laboratories simulated this process, showing that it could potentially redirect even large asteroids to prevent catastrophic impacts on Earth. Space.com reports: In a new study, the researchers employed the Z machine at Sandia National Laboratory, the most powerful laboratory source of radiation in the world. It generates powerful electric pulses, magnetic fields and X-rays to find out how materials react under high pressures and temperatures. "At present, there is only one way to generate an intense enough X-ray burst to do an experiment like this, and that's using the Z Machine," said [Nathan Moore, a physicist at Sandia National Laboratories in Albuquerque, N.M.]. The scientists used electrical pulses from the Z machine to generate powerful magnetic fields. These in turn compressed argon gas to generate plasma, the same form of matter that makes up lightning and stars. This argon plasma produced the X-ray burst the researchers needed to simulate a similar one from a nuclear explosion.

"You have to concentrate a lot of power, about 80 trillion watts, into a very small space, the size of a pencil lead, and very quickly, about 100 billionths of second, to generate a hot enough argon plasma, several millions of degrees, to make a powerful enough X-ray burst to heat the asteroid material surface to tens of thousands of degrees to give it enough push," Moore said. The scientists hung up a pair of targets in a vacuum, each 0.47 inches (12 millimeters) wide -- one made of quartz, the other of fused silica. These materials are similar in composition to known asteroids. Previous attempts to study various asteroid deflection strategies all held targets fixed in place, "which wasn't very realistic," Moore said. "After all, asteroids in outer space aren't attached to anything. Besides, how would a mock asteroid accelerate realistically if it was anchored down?"

To overcome this problem, the researchers devised what they called "X-ray scissors." They hung the targets up using thin metal foil just 13 microns thick, or about one-eighth the thickness of an average human hair. This foil vaporized when the X-rays hit it, freeing the targets to accelerate naturally in space. The X-ray pulses generated vapor plumes from each target and accelerated each one to about 155 mph (250 km/h), matching computational predictions. "The ability to deflect miniature asteroids in a laboratory using the Z Machine is unlike anything else you can do anywhere else on Earth," Moore said. Scaling these findings up to a 2.5-mile-wide (4 kilometer) asteroid, with a 1 megaton nuclear bomb exploding about 1.25 miles (2 km) from its surface, the researchers suggested the resulting push could help deflect dangerous asteroids away from Earth.

"For reference, a 4-km [2.5-mile] asteroid is predicted to be large enough to cause global devastation and possible disruption of civilization, according to the NASA Planetary Defense Strategy and Action Plan," Moore said. Moore noted that asteroids come in a variety of compositions. "This new technique can be used to investigate the deflection response of different asteroid materials," he said. "Understanding how different asteroid materials vaporize and deflect will be critical for preparing for a planetary defense mission, should the need arise." The study has been published in the journal Nature Physics.

silverjacket writes: A feature for The New Yorker describes a plan to use robots to mine lunar materials and build a radio telescope on the far side of the moon that will help answer questions about the early universe. An excerpt from the story: he dream of a lunar telescope dates to the nineteen-sixties. The moon has the advantage of being hundreds of thousands of miles away from earthly electronics; on the far side of the moon, in particular, there's virtually no noise from human technology or the Earth's magnetosphere. After the Apollo landings, however, interest in the moon waned. Jack Burns, an astrophysicist who is now at the University of Colorado Boulder, has been advocating for a moon-based telescope since 1984. "I never, never would have guessed that it would take this long," he told me. "I just won't accept no for an answer." Today, Burns is the chief scientist of FarView, as well as the primary investigator of a sort of mini-FarView: FARSIDE, which would have one or two hundred antennas instead of a hundred thousand.

If FarView is built, it would be able to detect some of the oldest light in existence. The universe began 13.8 billion years ago as a dense, fast-expanding soup of matter and energy; around three hundred and eighty thousand years later, it had cooled enough for hydrogen atoms to hold together. After that came the Cosmic Dark Ages: millions of years without stars or galaxies, a period we know very little about. But hydrogen occasionally releases light with a wavelength of twenty-one centimetres -- radio waves. Some of that light is still around.

Because twenty-one-centimetre radiation is stretched by the steady expansion of the universe -- it's now tens to hundreds of metres long -- scientists can figure out how old it is, and how far away. (The longer the wavelength, the older the light and the more distant its source.) This means that if scientists can build a radio telescope on the moon, they will be able to create a three-dimensional picture of the early universe.

schwit1 shares a report SpaceNews with the caption: "Failures aren't failures if you learn from them." From the report: Chinese commercial rocket firm Deep Blue Aerospace conducted a first-stage rocket hop test Sunday, experiencing a partial failure during the final moments of landing. Deep Blue Aerospace carried out the test at 1:40 a.m. Eastern (0540 UTC) Sept. 22 at the firm's Ejin Banner Spaceport in Inner Mongolia using a Nebula-1 rocket first stage. Footage of the vertical liftoff, vertical landing test shows the rocket ascending to a predetermined altitude before shutting off two of the three engines used for the 179-second flight. Landing legs deployed as planned, and the stage hovered above its planned landing spot. However an anomaly during the final engine shutdown phase led to a higher-than-expected landing altitude, leading to partial damage. You can watch the landing attempt and explosion here.

Industrial civilisation is close to breaching a seventh planetary boundary, and may already have crossed it, according to scientists who have compiled the latest report on the state of the world's life-support systems. From a report: "Ocean acidification is approaching a critical threshold," particularly in higher-latitude regions, says the latest report on planetary boundaries. "The growing acidification poses an increasing threat to marine ecosystems." The report, from the Potsdam Institute for Climate Impact Research (PIK), builds on years of research showing there are nine systems and processes -- the planetary boundaries -- that contribute to the stability of the planet's life-support functions.

Thresholds beyond which they can no longer properly function have already been breached in six. Climate change, the introduction of novel entities, change in biosphere integrity and modification of biogeochemical flows are judged to be in high-risk zones, while planetary boundaries are also transgressed in land system change and freshwater change but to a lesser extent. All have worsened, according to the data. Stratospheric ozone depletion has remained stable, however, and there has been a slight improvement in atmospheric aerosol loading, the research says. At a briefing outlining the findings, Levke Caesar, a climate physicist at PIK and co-author of the report, said there were two reasons the levels of ocean acidification were concerning.

SpaceX plans to launch about five uncrewed Starship missions to Mars in two years, CEO Elon Musk said on Sunday. From a report: Earlier this month, Musk had said that the first Starships to Mars would launch in two years "when the next Earth-Mars transfer window opens."

The CEO on Sunday said that the first crewed mission timeline will depend upon the success of the uncrewed flights. If the uncrewed missions land safely, crewed missions will be launched in four years. However, in case of challenges, crewed missions will be postponed by another two years, Musk said.

An anonymous reader shared this story from SFGate: A boy who was kidnapped from an Oakland playground in 1951 has been found alive on the East Coast, a remarkable resolution to a mystery that has haunted his family for over half a century.

On February 21, 1951, 6-year-old Luis Armando Albino was playing with his older brother Roger at Jefferson Square Park. The boys had recently immigrated with their mother and four other siblings from Puerto Rico... That afternoon, Luis and 10-year-old Roger walked down the block from their home at 730 Brush Street to play in the park. They were approached by a woman in her 30s, wearing a green bandana over her hair, who began chatting with Luis in Spanish. She promised she would buy him candy if he came along with her, and little Luis agreed to join her. Wary, Roger trailed the pair for a while before returning home to alert an adult to the strange encounter. Oakland police were called by frantic family members and a search was immediately launched...

Antonia [the boy's mother] was convinced her son was alive. "She came once a week, then once a month, then at least once a year, to see the shake of the head, to have the answer 'no' translated for her although she could read it in the officers' faces," the Oakland Tribune wrote in 1966...

Decades passed.

In 2020, Luis' niece, Alida Alequin, took a DNA test on a whim, the Mercury News reported. The service returned several possible family members to the Oakland woman. One of them was a man who Alequin had never met. After some internet sleuthing, she began to suspect this man might be the missing uncle she'd heard so much about. She reached out to the man but didn't hear back.

Earlier this year, Alequin tried again. Armed with photos, she took her evidence to the Oakland Police Department's missing persons unit. In short order, the FBI and California Department of Justice were also investigating Alequin's lead. They discovered the man was living on the East Coast, had worked as a firefighter and served two tours in Vietnam with the Marine Corps. This week, the Mercury News first reported that a DNA test confirmed what Alequin suspected: This was Luis Albino.

In June, Luis flew to California to reunite with his family, among them his devoted brother Roger... For over 70 years, he lived on the East Coast believing he was the son of another couple....

When Luis met Alequin for the first time this summer, he held her in an embrace. "Thank you," he said, "for finding me."

Polypropylene and polyethylene plastics "can be recycled," reports Ars Technica. But as "polyolefin" polymers, "the process can be difficult and often produces large quantities of the greenhouse gas methane.

"Now, researchers at the University of California, Berkeley have come up with a method of recycling these polymers that uses catalysts that easily break their bonds, converting them into propylene and isobutylene, which are gasses at room temperature. Those gasses can then be recycled into new plastics..." [T]he previous catalysts were expensive metals that did not remain pure long enough to convert all of the plastic into gas. Using sodium on alumina followed by tungsten oxide on silica proved much more economical and effective, even though the high temperatures required for the reaction added a bit to the cost. In both plastics, exposure to sodium on alumina broke each polymer chain into shorter polymer chains and created breakable carbon-carbon double bonds at the ends. The chains continued to break over and over.

Both then underwent a second process known as olefin metathesis. They were exposed to a stream of ethylene gas flowing into a reaction chamber while being introduced to tungsten oxide on silica, which resulted in the breakage of the carbon-carbon bonds. The reaction breaks all the carbon-carbon bonds in polyethylene and polypropylene, with the carbon atoms released during the breaking of these bonds ending up attached to molecules of ethylene... The entire chain is catalyzed until polyethylene is fully converted to propylene, and polypropylene is converted to a mixture of propylene and isobutylene. This method has high selectivity — meaning it produces a large amount of the desired product.

That means propylene derived from polyethylene, and both propylene and isobutylene derived from polypropylene. Both of these chemicals are in high demand, since propylene is an important raw material for the chemical industry, while isobutylene is a frequently used monomer in many different polymers, including synthetic rubber and a gasoline additive.
"Because plastics are often mixed at recycling centers, the researchers wanted to see what would happen if polypropylene and polyethylene underwent isomerizing ethenolysis together," the article adds. "The reaction was successful, converting the mixture into propylene and isobutylene, with slightly more propylene than isobutylene." The reaction worked, even if there were contaminants from other plastics. And "When the research team increased the scale of the experiment, it produced the same yield, which looks promising for the future...."

The researchers hope this some day could reduce the demand for chemicals derived from fossil fuels.

Thanks to Slashdot reader echo123 for sharing the article.

"In all likelihood, in the next 25 years, we'll find evidence of life on another planet..." begins a new essay by author Dave Eggers in the Washington Post.

"In more than a dozen conversations with some of the best minds in astrophysics, I did not meet anyone who was doubtful about finding evidence of life elsewhere — most likely on an exoplanet beyond our solar system. It was not a matter of if. It was a matter of when." [A]ll evidence points to us getting closer, every year, to identifying moons in our solar system, or exoplanets beyond it, that can sustain life. And if we don't find conditions for life on the moons near us, we'll find it on exoplanets — that is, planets outside our solar system. Within the next few decades, we'll likely find an exoplanet that has an atmosphere, that has water, that has carbon and methane and oxygen. Or some combination of those things.

And thus, the conditions for life. In a few years, NASA will launch the Nancy Grace Roman Space Telescope, which will have a panoramic field of vision a hundred times greater than the Hubble Space Telescope. And on the Nancy Grace Roman Space Telescope — we'll call it Roman from here on out — there will be a coronagraph, a device designed to perform something called, beautifully, starlight suppression. Starlight suppression is the blocking of the rays of a faraway star so that we can see behind it and around it. Once we can master starlight suppression, with Roman and NASA's next astrophysics flagship, the Habitable Worlds Observatory, we'll find the planets where life might exist.

To recap: For thousands of years, humans have wondered whether life is possible elsewhere in the universe, and now we're within striking distance of being able to say not only yes, but here.

And yet this is not front-page news. I didn't really know how close we were to this milestone until I visited the Jet Propulsion Laboratory in Pasadena, Calif., on a hot and dry day in June...
Eggers' article is part of an ongoing series called "Who is government?" (For the series Michael Lewis also profiled the uncelebrated number-crunchers at the U.S. Department of Labor, while Casey Cep wrote about the use of DNA to identify the remains of World War II soldiers for America's Veteran Affairs' department's.) But this week Eggers wrote that the work being done at NASA's Jet Propulsion Laboratory "is the most inspiring research and exploration being done by any humans on our planet..."

"No billionaires will fund work like this because there's no money in it. This is government-funded research to determine how the universe was created and whether we are alone in it. If NASA and JPL were not doing it, it would not be done."

Eggers emphasizes later that "doesn't mean it's intelligent life, or even semi-intelligent life. It could be bacteria, or some kind of interstellar sea cucumber. But whatever form it takes, we are close to finding it..."

Friday America's Federal Trade Commission brought action against three companies for "anticompetitive and unfair" practices "that have artificially inflated the list price of insulin."

For years, many of the millions of Americans who need insulin to survive "have been forced to pay exorbitant prices for a product that's inexpensive to make," writes NPR. "Now, the federal government is targeting one part of the system behind high insulin prices." While out-of-pocket costs have gone down for many people to $35 a month, questions remain on how the drug became so expensive in the first place. In a new lawsuit filed Friday, the Federal Trade Commission said it's going after one link in the chain: pharmacy benefit managers. The FTC brought action against the top pharmacy benefit managers (PBMs) — CVS Health's Caremark Rx, Cigna's Express Scripts, and United Health Group's OptumRx — saying the companies created a "perverse drug rebate system" that artificially inflates the cost of insulin. If the suit is successful, it could further drive down costs for patients at the pharmacy counter.

PBMs are essentially the middlemen between drug manufacturers and insurance providers. Their job is to reduce drug prices. But the process is complex and opaque, and critics say they're actually driving prices up for patients. The FTC said a big issue is that PBMs' revenue is tied to rebates and fees — which are based on a percentage of a drug's list price. Essentially, in the case of insulin, when the drug costed more, it generated higher rebates and fees for PBMs. "Even when lower list price insulins became available that could have been more affordable for vulnerable patients, the PBMs systemically excluded them in favor of high list price, highly rebated insulin products," the FTC said in a press release on Friday.

The three PBMs named in the FTC lawsuit make up about 80% of the market. According to the suit, the PBMs collected billions of dollars in rebates and fees while insulin became increasingly unaffordable. Over the last two decades, the cost of the lifesaving drug shot up 600% — forcing many Americans with diabetes to ration their medication and jeopardize their health. In 2019, one 1 of 4 insulin patients was unable to afford their medication, according to the FTC. Some people have died.
The FTC's statement says the companies "have abused their economic power by rigging pharmaceutical supply chain competition in their favor, forcing patients to pay more for life-saving medication... While PBM respondents collected billions in rebates and associated fees according to the complaint, by 2019 one out of every four insulin patients was unable to afford their medication..."

"[A]ll drug manufacturers should be on notice that their participation in the type of conduct challenged here raises serious concerns, and that the Bureau of Competition may recommend suing drug manufacturers in any future enforcement actions."

It's hypothetically capable of "delivering an exquisite portrait of the detailed surface features of any exoplanet within 100 light-years..." writes Space.com.

"It would be better than any telescope we could possibly build in any possible future for the next few hundred years..." While the sun may not look like a traditional lens or mirror, it has a lot of mass. And in Einstein's theory of general relativity, massive objects bend space-time around them. Any light that grazes the surface of the sun gets deflected and, instead of continuing in a straight line, heads toward a focal point, together with all the other light that grazes the sun at the same time... The "solar gravitational lens" leads to an almost unbelievably high resolution. It's as if we had a telescope mirror the width of the entire sun. An instrument positioned at the correct focal point would be able to harness the gravitational warping of the sun's gravity to allow us to observe the distant universe with a jaw-dropping resolution of 10^-10 arcseconds. That's roughly a million times more powerful than the Event Horizon Telescope.

Of course, there are challenges with using the solar gravitational lens as a natural telescope. The focal point of all this light bending sits 542 times greater than the distance between Earth and the sun. It's 11 times the distance to Pluto, and three times the distance achieved by humanity's most far-flung spacecraft, Voyager 1, which launched in 1977. So not only would we have to send a spacecraft farther than we ever have before, but it would have to have enough fuel to stay there and move around. The images created by the solar gravitational lens would be spread out over tens of kilometers of space, so the spacecraft would have to scan the entire field to build up a complete mosaic image.

Plans to take advantage of the solar lens go back to the 1970s. Most recently, astronomers have proposed developing a fleet of small, lightweight cubesats that would deploy solar sails to accelerate them to 542 AU. Once there, they would slow down and coordinate their maneuvers, building up an image and sending the data back to Earth for processing...

The telescope already exists — we just have to get a camera in the right position.
Thanks to Tablizer (Slashdot reader #95,088) for sharing the article.

The Washington Post reports: An international team of scientists published a peer-reviewed paper Thursday saying genetic evidence indicates the coronavirus pandemic most likely originated with a natural spillover from an animal or animals sold in a market in Wuhan, China, where many of the first human cases of covid-19 were identified. The paper, which appears in the journal Cell, does not claim to prove conclusively that the pandemic began in the Huanan Seafood Wholesale Market, and it is unlikely to end the acrimonious and politicized debate over the coronavirus's origin... "The results we see are consistent with infected animals, but we cannot prove that they were," said Florence Débarre, an evolutionary biologist at the French National Center for Scientific Research and a co-author of the new paper...

Many of the 23 authors of the paper are known to have long supported a market origin for the virus. In an informal report in March 2023, they presented a central feature of the genetic data — the confirmation that animals potentially capable of triggering a pandemic were in the market... The new paper in Cell is longer, more comprehensive, probes a broader range of questions, and includes more data from the market and early-patient cases than the international team's informal 2023 report, Débarre said. Both the earlier and the new reports document that traces of the virus were found clustered in a section of the Huanan Seafood Wholesale Market where genetic traces of animals were also found. Several of those species — raccoon dogs, rabbits and dogs — are known to be susceptible to infection with SARS-CoV-2, the virus that causes covid. Raccoon dogs have also been shown experimentally to be capable of transmitting the virus. A significant element of the new paper is an analysis of when the pandemic began. Scientists can study mutations of the coronavirus, which evolves at a relatively steady rate, to estimate when the millions of genomes deposited in databases had the most recent common ancestor. That genetic evidence points to mid-November 2019 as the most likely time the virus spilled into humans and began spreading, and there could have been two or more spillover events, the researchers said.

"The timing of the origin of the market outbreak is genetically indistinguishable from the timing of the origin of the pandemic as a whole," the report states. There are many independent lines of evidence pointing to the market as the epicenter of the pandemic, said Kristian Andersen, an infectious-disease researcher at Scripps Research in La Jolla, Calif., and a co-author of the report in Cell. No previous virus spillover has been so well-documented, he said. "Of any previous outbreak, pandemic, you name it, we don't have this level of granularity," he said. "We can narrow it down to a single market, and narrow it down to a section in that market, and maybe even narrow it down to a single stall in that market. That is mind-boggling...." The genetic evidence, the new report contends, supports the hypothesis that SARS-CoV-2 emerged in the same way that SARS-CoV-1 — which sickened people in 2002-2003 but was extinguished before it could cause a full-blown pandemic — is widely believed to have started, from animals sold in a market.

The authors contend the world needs to take more aggressive action to shut down the illegal trade in wildlife to lower the risk of another catastrophic pandemic... There is no evidence that the virus, or its progenitor, was inside a laboratory before the outbreak.... "To the question — Did it come from a lab or come from a market? — I think we already knew the answer to that," Andersen said. "Yep, it's the market. It's natural, as we've previously seen happen."
One co-author posted a summary on X.com "If you don't want to read the papers."

• "Early cases centered around the market (not a lab)"

• "Environmental swabs that tested positive for SARS-CoV-2 clustered in the corner of the market where animals were sold."

• "There were 2 lineages of SARS2 that spilled over separately at Huanan."

Slashdot first covered Saul Justin Newman's work in 2019.

Now a senior research fellow at the Centre for Longitudinal Studies at University College London, Newman was recognized last week for research finding that most claims of people living over 105 are wrong. Newman's research was honored with an Ig Nobel Prize (awarded for research that makes people "laugh then think") — which led to a thought-provoking interview in the Conversation: Newman: In general, the claims about how long people are living mostly don't stack up. I've tracked down 80% of the people aged over 110 in the world (the other 20% are from countries you can't meaningfully analyse). Of those, almost none have a birth certificate. In the U.S. there are over 500 of these people; seven have a birth certificate. Even worse, only about 10% have a death certificate.

The epitome of this is blue zones, which are regions where people supposedly reach age 100 at a remarkable rate. For almost 20 years, they have been marketed to the public. They're the subject of tons of scientific work, a popular Netflix documentary, tons of cookbooks about things like the Mediterranean diet, and so on. Okinawa in Japan is one of these zones. There was a Japanese government review in 2010, which found that 82% of the people aged over 100 in Japan turned out to be dead. The secret to living to 110 was, don't register your death. [Newman says later that "In Okinawa, the best predictor of where the centenarians are is where the halls of records were bombed by the Americans during the war..."] The Japanese government has run one of the largest nutritional surveys in the world, dating back to 1975. From then until now, Okinawa has had the worst health in Japan. They've eaten the least vegetables; they've been extremely heavy drinkers....

With the Greeks, by my estimates at least 72% of centenarians were dead, missing or essentially pension-fraud cases... According to the Greek minister that hands out the pensions, over 9,000 people over the age of 100 are dead and collecting a pension at the same time. In Italy, some 30,000 "living" pension recipients were found to be dead in 1997. Regions where people most often reach 100-110 years old are the ones where there's the most pressure to commit pension fraud, and they also have the worst records.
So what's the truth on human longevity? "The question is so obscured by fraud and error and wishful thinking that we just do not know," Newman answers (suggesting physicists "develop a measure of human age that doesn't depend on documents.") In the end the truth may be much more ordinary. "Longevity is very likely tied to wealth. Rich people do lots of exercise, have low stress and eat well."

Newman also says that if the scientific community won't acknowledge their errors during his lifetime, "I guess I'll just get someone to pretend I'm still alive until that changes."

Thanks to long-time Slashdot reader schwit1 for sharing the news.

An anonymous reader shares a report: CERN, the European particle-physics collaboration that operates the Large Hadron Collider, will expel hundreds of Russian-affiliated scientists from its laboratories. The Geneva-based organization decided to cut ties with Moscow after Russia's 2022 invasion of Ukraine, ending nearly 60 years of collaboration, and the agreements are now lapsing.

A small asteroid, 2024 PT5, will temporarily become a mini-moon for Earth, orbiting in a horseshoe shape from September 29 to November 25, 2024. CBS News reports: Researchers at the Asteroid Terrestrial-impact Last Alert System, an asteroid monitoring system funded by NASA, spotted the asteroid using an instrument in Sutherland, South Africa and labeled it 2024 PT5. Scientists from the Universidad Complutense de Madrid have tracked the asteroid's orbit for 21 days and determined its future path. 2024 PT5 is from the Arjuna asteroid belt, which orbits the sun, according to their study published in Research Notes of the AAs. But Earth's gravitational pull will draw 2024 PT5 towards it and, much like our moon, it will orbit our planet -- but only for 56.6 days. 2024 PT5, which is larger than some of the other mini-moons, will also return to Earth's orbit -- in 2055. [...]

The study's lead author Carlos de la Fuente Marcos told Space.com the mini-moon will be too small to see with amateur telescopes or binoculars but professional astronomers with stronger tools will be able to spot it.

An anonymous reader quotes a report from CBC News: Inside a bustling unit at St. Michael's Hospital in downtown Toronto, one of Shirley Bell's patients was suffering from a cat bite and a fever, but otherwise appeared fine -- until an alert from an AI-based early warning system showed he was sicker than he seemed. While the nursing team usually checked blood work around noon, the technology flagged incoming results several hours beforehand. That warning showed the patient's white blood cell count was "really, really high," recalled Bell, the clinical nurse educator for the hospital's general medicine program. The cause turned out to be cellulitis, a bacterial skin infection. Without prompt treatment, it can lead to extensive tissue damage, amputations and even death. Bell said the patient was given antibiotics quickly to avoid those worst-case scenarios, in large part thanks to the team's in-house AI technology, dubbed Chartwatch. "There's lots and lots of other scenarios where patients' conditions are flagged earlier, and the nurse is alerted earlier, and interventions are put in earlier," she said. "It's not replacing the nurse at the bedside; it's actually enhancing your nursing care."

A year-and-a-half-long study on Chartwatch, published Monday in the Canadian Medical Association Journal, found that use of the AI system led to a striking 26 percent drop in the number of unexpected deaths among hospitalized patients. The research team looked at more than 13,000 admissions to St. Michael's general internal medicine ward -- an 84-bed unit caring for some of the hospital's most complex patients -- to compare the impact of the tool among that patient population to thousands of admissions into other subspecialty units. "At the same time period in the other units in our hospital that were not using Chartwatch, we did not see a change in these unexpected deaths," said lead author Dr. Amol Verma, a clinician-scientist at St. Michael's, one of three Unity Health Toronto hospital network sites, and Temerty professor of AI research and education in medicine at University of Toronto. "That was a promising sign."

The Unity Health AI team started developing Chartwatch back in 2017, based on suggestions from staff that predicting deaths or serious illness could be key areas where machine learning could make a positive difference. The technology underwent several years of rigorous development and testing before it was deployed in October 2020, Verma said. Dr. Amol Verma, a clinician-scientist at St. Michael's Hospital who helped lead the creation and testing of CHARTwatch, stands at a computer. "Chartwatch measures about 100 inputs from [a patient's] medical record that are currently routinely gathered in the process of delivering care," he explained. "So a patient's vital signs, their heart rate, their blood pressure ... all of the lab test results that are done every day." Working in the background alongside clinical teams, the tool monitors any changes in someone's medical record "and makes a dynamic prediction every hour about whether that patient is likely to deteriorate in the future," Verma told CBC News.