According to a new study published Tuesday in the journal Nature Communications, six hours or less of sleep a night between the ages of 50, 60 and 70 was associated with a "30% increased dementia risk," independent of "sociodemographic, behavioral, cardiometabolic, and mental health factors," including depression. CNN reports: "Sleep is important for normal brain function and is also thought to be important for clearing toxic proteins that build up in dementias from the brain," said Tara Spires-Jones, who is deputy director of the Centre for Discovery Brain Sciences at The University of Edinburgh in Scotland, in a statement. Spires-Jones was not involved in the study. "What's the message for us all? Evidence of sleep disturbance can occur a long time before the onset of other clinical evidence of dementia," said Tom Dening, who heads the Centre for Dementia at the Institute of Mental Health at the University of Nottingham in the UK, in a statement.

"However, this study cannot establish cause and effect," said Denning, who was not involved in the study. "Maybe it is simply a very early sign of the dementia that is to come, but it's also quite likely that poor sleep is not good for the brain and leaves it vulnerable to neurodegenerative conditions like Alzheimer's disease." Because the new study followed a large population over an extended period of time, it adds "new information to the emerging picture" on the link between sleep deprivation and dementia, said Elizabeth Coulthard, an associate professor in dementia neurology at the University of Bristol in the UK, in a statement. "This means that at least some of the people who went on to develop dementia probably did not already have it at the start of the study when their sleep was first assessed," said Coulthard, who was not involved in the study. "It strengthens the evidence that poor sleep in middle age could cause or worsen dementia in later life," she said.

After pouring beer into a glass, streams of little bubbles appear and start to rise, forming a foamy head. As the bubbles burst, the released carbon dioxide gas imparts the beverage's desirable tang. But just how many bubbles are in that drink? The American Chemical Society: By examining various factors, researchers reporting in ACS Omega estimate between 200,000 and nearly 2 million of these tiny spheres can form in a gently poured lager. Worldwide, beer is one of the most popular alcoholic beverages. Lightly flavored lagers, which are especially well-liked, are produced through a cool fermentation process, converting the sugars in malted grains to alcohol and carbon dioxide. During commercial packaging, more carbonation can be added to get a desired level of fizziness. That's why bottles and cans of beer hiss when opened and release micrometer-wide bubbles when poured into a mug.

These bubbles are important sensory elements of beer tasting, similar to sparkling wines, because they transport flavor and scent compounds. The carbonation also can tickle the drinker's nose. Gerard Liger-Belair had previously determined that about 1 million bubbles form in a flute of champagne, but scientists don't know the number created and released by beer before it's flat. So, Liger-Belair and Clara Cilindre wanted to find out. The researchers first measured the amount of carbon dioxide dissolved in a commercial lager just after pouring it into a tilted glass, such as a server would do to reduce its surface foam. Next, using this value and a standard tasting temperature of 42 F, they calculated that dissolved gas would spontaneously aggregate to form streams of bubbles wherever crevices and cavities in the glass were more than 1.4 um-wide. Then, high-speed photographs showed that the bubbles grew in volume as they floated to the surface, capturing and transporting additional dissolved gas to the air above the drink. As the remaining gas concentration decreased, the bubbling would eventually cease. The researchers estimated there could be between 200,000 and 2 million bubbles released before a half-pint of lager would go flat.

An anonymous reader quotes a report from Phys.Org: A trio of researchers from Monash University and Deakin University has found that teaching children to play chess can reduce their aversion to risk. In their paper published in Journal of Development Economics, Asad Islam, Wang-Sheng Lee and Aaron Nicholas describe studying the impact of learning chess on 400 children in the U.K. The researchers found that most of the children experienced a decrease in risk aversion in a variety of game playing scenarios. They also noticed that playing chess also led to better math scores for some of the students and improvements in logic or rational thinking.

The researchers note that the game of chess is very well suited to building confidence in risk taking when there is reason to believe it might improve an outcome. In contrast, students also learned to avoid taking risks haphazardly, finding that such risks rarely lead to a positive outcome. They [...] line between good and poor risk-taking is especially evident in chess, which means that the more a person plays, the sharper their skills become. The researchers also found that the skills learned during chess playing appeared to be long lasting -- most of the children retained their decrease in risk aversion a full year after the end of their participation in the study. The researchers [...] did not find any evidence of changes in other cognitive skills, such as improvements in grades other than math or general creativity.

An anonymous reader quotes a report from Ars Technica: Extreme weather has become the new normal -- whether it's precipitation, drought, wind, heat, or cold. The question of how the ever-shrinking layer of Arctic sea ice has contributed to any of these changes has prompted some lively discussion over the past few years. Researchers have proposed that a weakened jet stream driven by vanishing Arctic sea ice might play a large role in extreme winter events like the descending polar vortex that struck North America earlier this year. But the idea hasn't held up well in light of more recent evidence.

But now, researchers have identified a direct link between extreme winter weather and sea ice loss. The 2018 "Beast of the East" winter storm hit Europe with record-breaking snowfall and low temperatures. And potentially as much as 88 percent of that snowfall originated from increased evaporation of the Barents Sea.

The working hypothesis is that Arctic sea ice acts as a cap for Arctic waters, limiting evaporation. Less sea ice and warmer Arctic temperatures mean more evaporation, potentially explaining the increased severity of winter storms like the Beast of the East. Until now, it's been tough to measure direct evidence linking sea ice loss to extreme European winters, but recent advances in technology are making this a little less challenging.

An anonymous reader quotes a report from ZDNet: A small miracle happened at 3:31am ET on Monday morning. Ingenuity, a tiny NASA helicopter, became the first powered aircraft to fly on another planet, Mars. This engineering feat was done with Linux, open-source software, and a NASA-built program based on the Jet Propulsion Laboratory's (JPL) open-source F (pronounced F prime) framework. GitHub CEO Nat Friedman and his team and the JPL Ingenuity crew took a long hard look into the helicopter's code and found that "nearly 12,000 developers on GitHub contributed to Ingenuity's software via open source. And yet, much like the first image of a black hole, most of these developers are not even aware that they helped make the first Martian helicopter flight possible."

They'll know now. Friedman wrote: "Today, we want to make the invisible visible. So, we have worked with JPL to place a new Mars 2020 Helicopter Mission badge on the GitHub profile of every developer who contributed to the specific versions of any open-source projects and libraries used by Ingenuity." The developer list was created by JPL providing GitHub with a comprehensive list of every version of every open source project used by Ingenuity. GitHub could then identify all the contributors who made these projects and their dependencies. Some of those honored, such as Linux's creator Linus Torvalds, are famous developers. Many others labor in obscurity -- but now their work is being recognized. Timothy Canham, a JPL embedded flight software engineer, notes Ingenuity's program is powered by a Qualcomm Snapdragon 801 running at 2.2GHz, which is "far faster than the Mars Perseverance's rover processors," according to ZDNet. The reason this older chip was used is because it meets NASA's High-Performance Spaceflight Computing (HPSC) radiation standards.

Canham also says the flight control software on Ingenuity runs at 500Hz. The flight software "is used to control the flight hardware and read sensors 500 times per second in order to keep the helicopter stable." Canham added: "We literally ordered parts from SparkFun [Electronics]. This is commercial hardware, but we'll test it, and if it works well, we'll use it."

NASA's first attempt to fly its "Ingenuity" helicopter on Mars was a success, marking what the space agency says is the first powered, controlled flight by an aircraft on another world. The BBC reports: The space agency is promising more adventurous flights in the days ahead. Ingenuity will be commanded to fly higher and further as engineers seek to test the limits of the technology. The rotorcraft was carried to Mars in the belly of Nasa's Perseverance Rover, which touched down in Jezero Crater on the Red Planet in February.

The demonstration saw the Mars-copter rise to just over 3m, hover, swivel 96 degrees, hover some more, and then set down. In all, it managed almost 40 seconds of flight, from take-off to landing. Getting airborne on the Red Planet is not easy. The atmosphere is very thin, just 1% of the density here at Earth. This gives the blades on a rotorcraft very little to bite into to gain lift. There's help from the lower gravity at Mars, but still -- it takes a lot of work to get up off the ground. Ingenuity was therefore made extremely light and given the power (a peak power of 350 watts) to turn those blades extremely fast - at over 2,500 revolutions per minute for this particular flight. Control was autonomous. The distance to Mars - currently just under 300 million km -- means radio signals take minutes to traverse the intervening space. Flying by joystick is simply out of the question.

Ingenuity has two cameras onboard. A black-and-white camera that points down to the ground, which is used for navigation, and a high-resolution colour camera that looks out to the horizon. Sample navigation images sent back to Earth revealed the helicopter's shadow on the floor of the crater as it came back in to land. Satellites will send home more pictures of the flight over the next day. There was only sufficient bandwidth in the orbiters' first overflight to return a short snatch of video from Perseverance, which was watching and snapping away from a distance of 65m. Longer sequences should become available in due course.

An anonymous reader shares a report: Now a second wave of Covid-19 has struck India, and the middle class dreams of tens of millions of people face even greater peril. Already, about 32 million people in India were driven into poverty by the pandemic last year, according to the Pew Research Center, accounting for a majority of the 54 million who slipped out of the middle class worldwide. The pandemic is undoing decades of progress for a country that in fits and starts has brought hundreds of millions of people out of poverty. Already, deep structural problems and the sometimes impetuous nature of many of Mr. Modi's policies had been hindering growth. A shrinking middle class would deal lasting damage. "It's very bad news in every possible way," said Jayati Ghosh, a development economist and professor at the University of Massachusetts Amherst. "It has set back our growth trajectory hugely and created much greater inequality."

The second wave presents difficult choices for India and Mr. Modi. India on Friday reported more than 216,000 new infections, another record. Lockdowns are back in some states. With work scarce, migrant workers are packing into trains and buses home as they did last year. The country's vaccination campaign has been slow, though the government has picked up the pace. Yet Mr. Modi appears unwilling to repeat last year's draconian lockdown, which left more than 100 million Indians jobless and which many economists blame for worsening the pandemic's problems. His government has also been reluctant to increase spending substantially like the United States and some other places, instead releasing a budget that would raise spending on infrastructure and in other areas but that also emphasizes cutting debt.

Slashdot reader quonset reminds us that NASA's Mars helicopter "is officially 'go' for flight!," according to the Twitter feed of the Perserverance Rover, which notes that its cameras are ready to film the historic event.

"Watch with the team as they receive data and find out if they were successful," adds NASA's official feed. "Meet us in mission control April 19 at 6:15am ET (10:15am UTC): Data from the first flight will return to Earth a few hours following the autonomous flight. A livestream will begin at 6:15 a.m. EDT (3:15 a.m. PDT), as the helicopter team prepares to receive the data downlink in the Space Flight Operations Facility at NASA's Jet Propulsion Laboratory (JPL). Watch on NASA Television, the agency app, website, and social media platforms, including YouTube and Facebook.

If the flight takes place April 19, a postflight briefing will be held at 2 p.m. EDT (11 a.m. PDT)...

The public and media also may ask questions on social media during the livestream and briefing using #MarsHelicopter. Find the latest schedule updates here.

The Perseverance rover will provide support during flight operations, taking images, collecting environmental data, and hosting the base station that enables the helicopter to communicate with mission controllers on Earth.
Update: And it's a success! "We've been talking for so long about our Wright Brothers moment on Mars, and here it is," said NASA Ingenuity Mars Helicopter project manager MiMi Aung. The Perserverance rover has already tweeted out a choppy video.

"Two satellites from the fast-growing constellations of OneWeb and SpaceX's Starlink dodged a dangerously close approach with one another in orbit," reported The Verge, citing representatives from both OneWeb and the U.S. Space Force.

UPDATE (April 22): SpaceX strongly disputes OneWeb's characterization of the event.

Below is the Verge's original report: On March 30th, five days after OneWeb launched its latest batch of 36 satellites from Russia, the company received several "red alerts" from the US Space Force's 18th Space Control Squadron warning of a possible collision with a Starlink satellite. Because OneWeb's constellation operates in higher orbits around Earth, the company's satellites must pass through SpaceX's mesh of Starlink satellites, which orbit at an altitude of roughly 550 km.

One Space Force alert indicated a collision probability of 1.3 percent, with the two satellites coming as close as 190 feet — a dangerously close proximity for satellites in orbit. If satellites collide in orbit, it could cause a cascading disaster that could generate hundreds of pieces of debris and send them on crash courses with other satellites nearby...

Space Force's urgent alerts sent OneWeb engineers scrambling to email SpaceX's Starlink team to coordinate maneuvers that would put the two satellites at safer distances from one another. While coordinating with OneWeb, SpaceX disabled its automated AI-powered collision avoidance system to allow OneWeb to steer its satellite out of the way, according to OneWeb's government affairs chief Chris McLaughlin... SpaceX's automated system for avoiding satellite collisions has sparked controversy, raising concerns from other satellite operators who say they have no way of knowing which way the system will move a Starlink satellite in the event of a close approach.

Aflorithmic, an AI-driven audio cloning startup, has created a digital version of Albert Einstein using AI voice cloning technology drawing on audio records of the famous scientist's actual voice. TechCrunch reports: Alforithmic says the "digital Einstein" is intended as a showcase for what will soon be possible with conversational social commerce. Which is a fancy way of saying deepfakes that make like historical figures will probably be trying to sell you pizza soon enough, as industry watchers have presciently warned. The startup also says it sees educational potential in bringing famous, long-deceased figures to interactive "life." Or, well, an artificial approximation of it -- the "life" being purely virtual and Digital Einstein's voice not being a pure tech-powered clone either; Alforithmic says it also worked with an actor to do voice modelling for the chatbot (because how else was it going to get Digital Einstein to be able to say words the real-deal would never even have dreamt of saying -- like, er, "blockchain"?). So there's a bit more than AI artifice going on here too.

In a blog post discussing how it recreated Einstein's voice the startup writes about progress it made on one challenging element associated with the chatbot version -- saying it was able to shrink the response time between turning around input text from the computational knowledge engine to its API being able to render a voiced response, down from an initial 12 seconds to less than three (which it dubs "near-real-time"). But it's still enough of a lag to ensure the bot can't escape from being a bit tedious. The report notes that the video engine powering the 3D character rendering components of this "digital human" version of Einstein is the work of another synthesized media company, UneeQ, which is hosting the interactive chatbot version on its website.

AmiMoJo shares a report from The Guardian: The whitest-ever paint has been produced by academic researchers, with the aim of boosting the cooling of buildings and tackling the climate crisis. The new paint reflects 98% of sunlight as well as radiating infrared heat through the atmosphere into space. In tests, it cooled surfaces by 4.5C below the ambient temperature, even in strong sunlight. The researchers said the paint could be on the market in one or two years. Currently available reflective white paints are far better than dark roofing materials, but only reflect 80-90% of sunlight and absorb UV light. This means they cannot cool surfaces below ambient temperatures. The new paint does this, leading to less need for air conditioning and the carbon emissions they produce, which are rising rapidly.

The new paint was revealed in a report in the journal ACS Applied Materials & Interfaces. Three factors are responsible for the paint's cooling performance. First, barium sulphate was used as the pigment which, unlike conventional titanium dioxide pigment, does not absorb UV light. Second, a high concentration of pigment was used -- 60%. Third, the pigment particles were of varied size. The amount of light scattered by a particle depends on its size, so using a range scatters more of the light spectrum from the sun. The researchers said the ultra-white paint uses a standard acrylic solvent and could be manufactured like conventional paint. They claim the paint would be similar in price to current paints, with barium sulphate actually cheaper than titanium dioxide. They have also tested the paint's resistance to abrasion, but said longer-term weathering tests were needed to assess its long-term durability.

NASA on Friday selected SpaceX to build spacecraft that would land astronauts on the moon for the first time since the last Apollo mission, according to a source selection document obtained by The Washington Post. From the report: The contract marks another major victory for the hard-charging company that vaults it to the top tier of the nation's aerospace companies and solidifies it as one of the space agency's most trusted partners. In winning the $2.9 billion contract, SpaceX beat out Jeff Bezos' Blue Origin, which had formed what it called a "national team" by partnering with aerospace giants Lockheed Martin, Northrop Grumman and Draper. SpaceX also won over Dynetics, a defense contractor based in Huntsville, Ala. NASA had originally chosen all three companies for the initial phase of the contract, and was expected to choose two of them to build the lunar lander. In other major programs, NASA has chosen multiple providers to foster competition and to ensure it has redundancy in case one can't deliver. But in choosing SpaceX alone, it sent a message that it fully trusts the growing company to fly its astronauts for its signature human exploration program -- Artemis, a campaign to return astronauts to the moon for the first time since 1972.

For the first time, scientists have estimated how many Tyrannosaurus rex, the so-called king of dinosaurs, once roamed the Earth. From a report: The number is staggering: 2.5 billion Tyrannosaurus rex lived and died during the roughly 2.4 million years the species survived on the planet, according to a new study set to be published in the journal Science on Friday. The study may help contextualize the fossil record and the rarity of finding certain fossilized prehistoric organisms, according to lead researcher Charles Marshall, director of the University of California Museum of Paleontology. "I mean, to me, it's just amazing we could have come up with a number," Marshall told Axios. "Some people have asked me, 'How does your number compare to other numbers of the total that have ever lived?' The answer is it doesn't because there weren't any."

Pfizer CEO Albert Bourla said people will "likely" need a booster dose of a Covid-19 vaccine within 12 months of getting fully vaccinated. His comments were made public Thursday but were taped April 1. From a report: Bourla said it's possible people will need to get vaccinated against the coronavirus annually. "A likely scenario is that there will be likely a need for a third dose, somewhere between six and 12 months and then from there, there will be an annual revaccination, but all of that needs to be confirmed. And again, the variants will play a key role," he told CNBC's Bertha Coombs during an event with CVS Health. "It is extremely important to suppress the pool of people that can be susceptible to the virus," Bourla said. The comment comes after Johnson & Johnson CEO Alex Gorsky told CNBC in February that people may need to get vaccinated against Covid-19 annually, just like seasonal flu shots. Researchers still don't know how long protection against the virus lasts once someone has been fully vaccinated.

An anonymous reader quotes a report from Ars Technica: Cases of COVID-19 are extremely rare among people who are fully vaccinated, according to a new data analysis by the Centers for Disease Control and Prevention. Among more than 75 million fully vaccinated people in the US, just around 5,800 people reported a "breakthrough" infection, in which they became infected with the pandemic coronavirus despite being fully vaccinated. The numbers suggest that breakthroughs occur at the teeny rate of less than 0.008 percent of fully vaccinated people -- and that over 99.992 percent of those vaccinated have not contracted a SARS-CoV-2 infection.

The figures come from a nationwide database that the CDC set up to keep track of breakthrough infections and monitor for any concerning signs that the breakthroughs may be clustering by patient demographics, geographic location, time since vaccination, vaccine type, or vaccine lot number. The agency will also be keeping a close eye on any breakthrough infections that are caused by SARS-CoV-2 variants, some of which have been shown to knock back vaccine efficacy. [...] The extraordinary calculation that 99.992 percent of vaccinated people have not contracted the virus may reflect that they all simply have not been exposed to the virus since being vaccinated. Also, there are likely cases missed in reporting. Still, the data is a heartening sign. As for the "breakthroughs," the agency says many of them occurred in older people, who are more vulnerable to COVID-19. There are some scattered through every age group, but more than 40 percent were in people ages 60 and above.

"We see [breakthroughs] with all vaccines," top infectious disease expert Anthony Fauci said in a press briefing earlier this week. "No vaccine is 100 percent efficacious or effective, which means that you will always see breakthrough infections regardless of the efficacy of your vaccine."

California and its partners are set to launch by 2023 two satellites to spot and monitor plumes of planet-warming carbon dioxide (CO2) and methane. "If all goes right, dozens more could follow," reports Science Magazine. From the report: The $100 million Carbon Mapper project, announced today and financed by private philanthropists including Michael Bloomberg, will advance efforts to track concentrated emissions of greenhouse gases, which rise from fossil fuel power plants, leaky pipelines, and abandoned wells. Previous satellites have lacked the resolution and focus to monitor point sources rigorously. [...] The satellites will be built and managed by Planet, a California company that already operates a constellation of Earth-imaging satellites. The spacecraft will rely on "hyperspectral" imaging spectrometers developed by NASA's Jet Propulsion Laboratory (JPL). Rather than gathering light in just a few discrete wavelength channels, like the human eye, these spectrometers capture reflected sunlight and subdivide it into more than 400 wavelength channels across the visible and into the infrared. The intensity of light across these channels can be tied to specific chemistries and reflect the abundances of certain gases in the air molecules below.

The satellites won't just measure gases in the air; they will also detect chemical signatures on the ground. By measuring the intensity of green chlorophyll or detecting the signatures for excess salts or fungus, for example, researchers will be able to evaluate the health of crops and forests. They can prospect for minerals in remote regions. They can map and identify different coral and algae species, and they can track dust and soot. Even snow and ice pops out in these sensors, says Robert Green, a remote-sensing scientist at JPL. "Snow is one of the most colorful materials on Earth if you look beyond visible light."

The first two Carbon Mapper satellites will each be roughly the size of a washing machine, weighing up to 200 kilograms. They will provide imagery with a resolution of 30 meters but won't offer global coverage at first. Instead, they will target regions known to host superemitters, like power plants, oil and gas drilling, or livestock operations. The regions will be revisited every few weeks to start. All emission data, calculated from the plume intensity and length, will be made publicly available -- in the hopes that governments and businesses will do more to staunch leaks and tamp down discharges. [...] Should Carbon Mapper's first two satellites prove successful, Planet envisions building a commercial constellation of similar satellites that would revisit every spot on the planet once a day, and selling those data to regulators and companies.

Researchers at the University of Washington have partnered with Apple to study how Apple Watch may be used to predict illnesses such as coronavirus, or flu. Apple Insider reports: "The goal of the study is to see if the information collected by the Apple Watch and iPhone can detect early signs of respiratory illnesses like COVID-19," say the organizers on the recruitment page. The study is focusing on the Seattle area because residents "may have higher than normal risk of respiratory illness because of frequent exposure to other people through work or other activities, health conditions, or other factors."

This Apple Respiratory Study is expected to take "up to six months." During the study, participants will be required to periodically answer survey questions in the Apple Research iPhone app. If participants get sick while enrolled in the study, they will be sent an in-home testing kit for COVID-19 and other respiratory illnesses. But, this will likely assist the study further, as sick participants will be asked to "take some additional health measurements using your Apple Watch."

If your heart stops en route to Mars, rest assured that researchers have considered how to carry out CPR in space. (One option is to plant your feet on the ceiling and extend your arms downwards to compress the patient's chest.) From a report: Astronauts, because of their age range and high physical fitness, are unlikely to suffer a stroke or have their appendix suddenly explode. That's good because, if it does happen, they're in the realm of what Jonathan Scott -- head of the medical projects and technology team at the European Space Agency -- describes as 'treatment futility.' In other words: there's nothing anyone can do about it. On the ISS, when medical incidents arise, astronauts can draw on the combined expertise of a host of medical experts at Nasa. "The patient is on the space station, the doctor is on the ground, and if there's a problem the patient consults the doctor," says Scott. By the time astronauts reach Mars, there'll be a 40-minute time lag in communications, if it's possible to make contact at all. "We have to begin preparing for not only being able to diagnose things in spaceflight but also to treat them as well," Scott says.

Artificial intelligence is likely to be a part of the solution. If you're imagining the holographic doctor from Star Trek, downgrade your expectations, at least for the next few decades. Kris Lehnhardt, the element scientist for exploration medical capability at Nasa, says: "We are many, many, many years away from: please state the nature of the medical emergency." Emmanuel Urquieta is deputy chief scientist at the Translational Institute for Space Health (TRISH), a Nasa-funded program which conducts research into healthcare for deep space missions. While full AI may be a way off, Urquieta believes some form of artificial intelligence will still play a crucial role. "It's going to be essential for a mission to Mars," he says. While the crew for a mission to Mars will likely include a medical doctor, he explains: "No single physician can know everything." And, of course: "What happens if that astronaut gets sick?" Research projects funded by TRISH include Butterfly iQ, a handheld ultrasound device for use by non-medical personnel to make diagnoses that would otherwise require bulky equipment and a trained operator. VisualDx is an AI diagnostics tool originally developed to analyse images and identify skin conditions. The technology is now being adapted to help astronauts diagnose a wide range of conditions most commonly encountered in space, without an internet connection.

Slashdot reader omfglearntoplay shares an excerpt from a BBC article that explores the new technologies that may have already introduced genetic errors to the human gene pool. The article starts by mentioning He Jiankui, a Shenzhen researcher who was sentenced to prison in late 2019 for creating the world's first genetically altered babies. From the report: Jiankui had made the first genetically modified babies in the history of humankind. After 3.7 billion years of continuous, undisturbed evolution by natural selection, a life form had taken its innate biology into its own hands. The result was twin baby girls who were born with altered copies of a gene known as CCR5, which the scientist hoped would make them immune to HIV. But things were not as they seemed. In the years since, it's become clear that Jiankui's project was not quite as innocent as it might sound. He had broken laws, forged documents, misled the babies' parents about any risks and failed to do adequate safety testing. However, arguably the biggest twist were the mistakes. It turns out that the babies involved, Lulu and Nana, have not been gifted with neatly edited genes after all. Not only are they not necessarily immune to HIV, they have been accidentally endowed with versions of CCR5 that are entirely made up -- they likely do not exist in any other human genome on the planet. And yet, such changes are heritable -- they could be passed on to their children, and children's children, and so on.

In fact, there have been no shortage of surprises in the field. From the rabbits altered to be leaner that inexplicably ended up with much longer tongues to the cattle tweaked to lack horns that were inadvertently endowed with a long stretch of bacterial DNA in their genomes (including some genes that confer antibiotic resistance, no less) -- its past is riddled with errors and misunderstandings. More recently, researchers at the Francis Crick Institute in London warned that editing the genetics of human embryos can lead to unintended consequences. By analyzing data from previous experiments, they found that approximately 16% had accidental mutations that would not have been picked up via standard tests. Why are these mistakes so common? Can they be overcome? And how could they affect future generations?

fahrbot-bot shares a report from Phys.Org: Why is sugar not transparent? Because light that penetrates a piece of sugar is scattered, altered and deflected in a highly complicated way. However, as a research team from TU Wien (Vienna) and Utrecht University (Netherlands) has now been able to show, there is a class of very special light waves for which this does not apply: for any specific disordered medium -- such as the sugar cube you may just have put in your coffee -- tailor-made light beams can be constructed that are practically not changed by this medium, but only attenuated. The light beam penetrates the medium, and a light pattern arrives on the other side that has the same shape as if the medium were not there at all. This idea of "scattering-invariant modes of light" can also be used to specifically examine the interior of objects. The results have now been published in the journal Nature Photonics. This method of finding light patterns that penetrate an object largely undisturbed could also be used for imaging procedures. "In hospitals, X-rays are used to look inside the body -- they have a shorter wavelength and can therefore penetrate our skin. But the way a light wave penetrates an object depends not only on the wavelength, but also on the waveform," says Matthias Kuhmayer, who works as a Ph.D. student on computer simulations of wave propagation. "If you want to focus light inside an object at certain points, then our method opens up completely new possibilities. We were able to show that using our approach the light distribution inside the zinc oxide layer can also be specifically controlled."