"On Tuesday morning, all five layers of the James Webb Space Telescope were fully locked into place," writes Slashdot reader quonset. The BBC reports: There were many who doubted the wisdom of a design that included so many motors, gears, pulleys and cables. But years of testing on full-scale and sub-scale models paid dividends as controllers first separated the shield's different layers and then tensioned them. The fifth and final membrane was locked into place at 16:58 GMT. "The unfurling and securing of the sun shield is part of what NASA refers to as '29 days on the edge,' writes quonset, citing an article from CNN. "During the 29 days, Webb will set up shop, unfurling its giant gold mirror and the protective tennis court-size sunshield. This process involves thousands of parts that must function harmoniously, in the right sequence. Fortunately, each step can be controlled from the ground in case there are issues."

"The next step is the unboxing of the mirror which had to be folded to fit inside the nose cone of the rocket for launch. If all goes well, by the end of the weekend, the mirror will be in place and ready for testing before full operations begin."

The World Health Organization said a coronavirus variant found in France hasn't become much of a threat since it was first identified in November. From a report: The variant "has been on our radar," Abdi Mahamud, a WHO incident manager on Covid, said at a press briefing in Geneva on Tuesday. "That virus had a lot of chances to pick up." The variant was identified in 12 people in the southern Alps around the same time that omicron was discovered in South Africa last year. The latter mutation has since traveled the globe and kindled record levels of contagion, unlike the French one that researchers at the IHU Mediterranee Infection -- helmed by scientist Didier Raoult -- nicknamed IHU. The first patient identified with the variant was vaccinated and had just returned from Cameroon, IHU researchers wrote in a paper published on the medRxiv server in late December where they first drew attention to the atypical mutations.

An anonymous reader quotes a report from New Atlas: A new COVID-19 vaccine, developed by researchers from the Texas Children's Hospital and Baylor College of Medicine, is being offered patent-free to vaccine manufacturers across the world. Human trials have shown the vaccine to be safe and effective, with India already authorizing its use as production ramps up to over 100 million doses per month. The vaccine has been named Corbevax and it is based on a traditional protein-based technology that has been safely used for decades. Like other COVID-19 vaccines, Corbevax focuses on the coronavirus spike protein, but instead of using mRNA to direct our cells to produce those spike proteins internally it delivers lab-grown spike proteins to the body. The researchers took the gene that codes for the spike protein and engineered yeast to produce it. These proteins are collected, purified, and combined with an adjuvant to enhance immune responses. This exact method has been used to produce the hepatitis B vaccine for years.

In late 2020 the US research team developing the vaccine joined forces with India-based pharma company Biological E to begin clinical trials and establish manufacturing capacity. Across 2021 those clinical trials included several thousand participants and ultimately found Corbevax to be safe and effective at generating robust immune responses to SARS-CoV-2. The trial data was compared to an already approved vaccine called Covishield (the Indian-made version of Astrazeneca's well-known COVID-19 vaccine). Corbevax generated significantly fewer adverse effects than Covishield and produced superior immune responses. Neutralizing antibody responses to Corbevax indicate the vaccine should be at least 80 percent effective at preventing symptomatic COVID-19 from the Delta variant. Specific data against the Omicron variant is expected soon but it is hypothesized to be at least as effective as most currently available vaccines. Perhaps the most important feature of this new vaccine is the fact it has been developed as a patent-free product that can be easily manufactured by vaccine-producers around the world. The project has been described as "gift to the world" by researcher Peter Hotez. "India is the first country to issue emergency authorization to Corbevax and Biological E reportedly has 150 million doses ready to go, with production capacity set for 100 million doses per month from February," reports New Atlas.

According to data from Johns Hopkins University, more than 1 million people in the U.S. were diagnosed with COVID-19 on Monday. Bloomberg reports: The highly mutated variant drove U.S. cases to a record, the most -- by a large margin -- that any country has ever reported. Monday's number is almost double the previous record of about 590,000 set just four days ago in the U.S., which itself was a doubling from the prior week. It is also more than twice the case count seen anywhere else at any time since the pandemic began more than two years ago. The highest number outside the U.S. came during India's delta surge, when more than 414,000 people were diagnosed on May 7, 2021.

An anonymous reader quotes a report from Scientific American: Human sexual activity affects cognitive function, health, happiness and overall quality of life -- and, yes, there is also the matter of reproduction. The huge range of benefits is one reason researchers have become alarmed at declines in sexual activity around the world, from Japan to Europe to Australia. A recent study evaluating what is happening in the U.S. has added to the pile of evidence, showing declines from 2009 to 2018 in all forms of partnered sexual activity, including penile-vaginal intercourse, anal sex and partnered masturbation. The findings show that adolescents report less solo masturbation as well.

The decreases "aren't trivial," as the authors wrote in the study, published on November 19 in Archives of Sexual Behavior. Between 2009 and 2018, the proportion of adolescents reporting no sexual activity, either alone or with partners, rose from 28.8 percent to 44.2 percent among young men and from 49.5 percent in 2009 to 74 percent among young women. The researchers obtained the self-reported information from the National Survey of Sexual Health and Behavior and used responses from 4,155 people in 2009 and 4,547 people in 2018. These respondents to the confidential survey ranged in age from 14 to 49 years. The study itself did not probe the reasons for this trend. Scientific American spoke with the study's authors, Debby Herbenick and Tsung-chieh (Jane) Fu, about underlying factors that might explain these changes. Among the young, the researchers say social media, gaming and "rough sex" may contribute to this trend. The grief, health challenges, job loss and financial strain of the pandemic can all influence sexual interest and sex drive, too.

spth writes from a report via German publisher Heise: The Experimental Advanced Superconducting Tokamak (EAST) in Hefei, China has maintained a temperature of 70 million degrees celsius for 17 minutes at the end of 2021. It had previously held 120 million degrees celsius for 101 seconds and 160 million degrees celsius for 20 seconds. The goal is to keep 100 million degrees for one week. The purpose of the research at EAST is to support the International Thermonuclear Experimental Reactor (ITER) in Cadarache, France. The reactor maintained these temperatures for exactly 1,056 seconds, or 17 minutes, 36 seconds, notes the Institute of Plasma Physics Chinese Academy of Sciences in an announcement.

After deliberating for more than 40 hours over six days, jurors in the Elizabeth Holmes criminal trial have found Holmes guilty on four of 11 charges of defrauding the company's investors and patients. She was found not guilty on four counts. NPR reports: When the verdict was read, Holmes had no visible reaction. She sat masked in the courtroom and later hugged members of her family in the front row of the court. Holmes could face up to 20 years in prison, although legal experts say her sentence is likely to be less than that. During the nearly four-month federal trial in San Jose, jurors heard from over 30 witnesses called by prosecutors. Together, they painted Holmes as a charismatic entrepreneur who secured hundreds of millions of dollars in investment for a medical device that never delivered on her promises. When Theranos' technology fell short, the government argued, Holmes covered it up and kept insisting that the machines would transform how diseases are diagnosed through blood tests. The jury's decision followed seven days of deliberations. Still, the jury could not reach a unanimous decision on three charges, which will be resolved at a later date..

Holmes took the witness stand for more than 20 hours to defend herself. She accused her ex-boyfriend and former deputy at Theranos, Ramesh "Sunny" Balwani, of sexual abuse, saying that clouded her sense of judgement. Balwani faces a separate fraud trial in the same court in February. Holmes also showed remorse on the stand. She said she wished she had handled some key business matters differently. But she blamed others for the downfall of Theranos. She said lab directors whom she had trusted were the ones closest to the technology. And she said Balwani, not her, oversaw the company's financial forecasts, which were later discovered to be grossly inflated. Yet the government offered evidence that Holmes had an iron grip on Theranos' operations. Prosecutors argued she did not stop -- and even helped spread -- falsehoods about the company that misled investors into pouring millions into the startup. Theranos' value, once estimated at more than $9 billion, was ultimately squandered.

The New York Times: After a year of fertility treatments, Yael Geller was thrilled when she found out she was pregnant in November 2020. Following a normal ultrasound, she was confident enough to tell her 3-year-old son his "brother or sister" was in her belly. But a few weeks later, as she was driving her son home from school, her doctor's office called. A prenatal blood test indicated her fetus might be missing part of a chromosome, which could lead to serious ailments and mental illness. Sitting on the couch that evening with her husband, she cried as she explained they might be facing a decision on terminating the pregnancy. He sat quietly with the news. "How is this happening to me?" Ms. Geller, 32, recalled thinking. The next day, doctors used a long, painful needle to retrieve a small piece of her placenta. It was tested and showed the initial result was wrong. She now has a 6-month-old, Emmanuel, who shows no signs of the condition he screened positive for. Ms. Geller had been misled by a wondrous promise that Silicon Valley has made to expectant mothers: that a few vials of their blood, drawn in the first trimester, can allow companies to detect serious developmental problems in the DNA of the fetus with remarkable accuracy.

In just over a decade, the tests have gone from laboratory experiments to an industry that serves more than a third of the pregnant women in America, luring major companies like Labcorp and Quest Diagnostics into the business, alongside many start-ups. The tests initially looked for Down syndrome and worked very well. But as manufacturers tried to outsell each other, they began offering additional screenings for increasingly rare conditions. The grave predictions made by those newer tests are usually wrong, an examination by The New York Times has found. That includes the screening that came back positive for Ms. Geller, which looks for Prader-Willi syndrome, a condition that offers little chance of living independently as an adult. Studies have found its positive results are incorrect more than 90 percent of the time. Nonetheless, on product brochures and test result sheets, companies describe the tests to pregnant women and their doctors as near certain. They advertise their findings as "reliable" and "highly accurate," offering "total confidence" and "peace of mind" for patients who want to know as much as possible.

Some of the companies offer tests without publishing any data on how well they perform, or point to numbers for their best screenings while leaving out weaker ones. Others base their claims on studies in which only one or two pregnancies actually had the condition in question. These aren't the first Silicon Valley firms to try to build a business around blood tests. Years before the first prenatal testing company opened, another start-up, Theranos, made claims that it could run more than a thousand tests on a tiny blood sample, before it collapsed amid allegations of fraud. In contrast with Theranos, the science behind these companies' ability to test blood for common disorders is not in question. Experts say it has revolutionized Down syndrome screening, significantly reducing the need for riskier tests. However, the same technology -- known as noninvasive prenatal testing, or NIPT -- performs much worse when it looks for less common conditions. Most are caused by small missing pieces of chromosomes called microdeletions. Others stem from missing or extra copies of entire chromosomes. They can have a wide range of symptoms, including intellectual disability, heart defects, a shortened life span or a high infant mortality rate.

"Since joining NASA in 1980, Jim Green has seen it all," writes the New York Times. He has helped the space agency understand Earth's magnetic field, explore the outer solar system and search for life on Mars. As the new year arrived on Saturday, he bade farewell to the agency.

Over the past four decades, which includes 12 years as the director of NASA's planetary science division and the last three years as its chief scientist, he has shaped much of NASA's scientific inquiry, overseeing missions across the solar system and contributing to more than 100 scientific papers across a range of topics... One of Dr. Green's most recent significant proposals has been a scale for verifying the detection of alien life, called the "confidence of life detection," or CoLD, scale. [Green says scientists have to "stop screwing around with just crying wolf."]
Green has also published research suggesting it's possible to terraform Mars with a giant magnetic shield blocking the sun (to stop it from stripping the Mars atmosphere and creating habitable temperatures).

"Yeah, it's doable," he explains to the Times:

"Stop the stripping, and the pressure is going to increase. Mars is going to start terraforming itself. That's what we want: the planet to participate in this any way it can. When the pressure goes up, the temperature goes up... If you didn't need a spacesuit, you could have much more flexibility and mobility. The higher temperature and pressure enable you to begin the process of growing plants in the soils.

"There are several scenarios on how to do the magnetic shield. I'm trying to get a paper out I've been working on for about two years. It's not going to be well received. The planetary community does not like the idea of terraforming anything.

"But you know. I think we can change Venus, too, with a physical shield that reflects light. We create a shield, and the whole temperature starts going down."

Time reports on virtual doppelgangers — also known as "digital twins". (Alternate URL here.) Created by feeding video, images, blueprints or other data into advanced 3-D mapping software, digital twins are being used in medicine to replicate and study internal organs. They've propelled engineers to devise car and plane prototypes — including Air Force fighter jets — more quickly. They allow architects and urban planners to envision and then build skyscrapers and city blocks with clarity and precision. And this year, digital twins began to break into the mainstream of manufacturing and research. In April, chipmaker Nvidia launched a version of its Omniverse 3-D simulation engine that allows businesses to build 3-D renderings of their own — including digital twins. Amazon Web Services announced a competing service, the IoT TwinMaker, in November...

The need was always there. In the 1960s, NASA created physical replicas of spaceships and connected them to simulators so that if a crisis ensued on the actual vehicle hundreds of thousands of miles away, a team could workshop solutions on the ground. Dave Rhodes, the senior vice president of digital twins at Unity Technologies, a video-game and 3-D-platform company, says that digital-twin technology is only now being widely released because of several confluent factors, including the increased computing power of cloud-based systems, the spread of 5G networks, improvements in 3-D rendering and the remote work demands of COVID-19....

Digital-twin technology is being trialed across the medical landscape, for planning surgical procedures and exploring the heart risks of various drugs... Digital twins are also being used in other complex and potentially dangerous machines, from nuclear reactors in Idaho to wind turbines in Paris.... Digital twin humans are coming too: the NFL and Amazon Web Services have created a "digital athlete" that will run infinite scenarios to better understand and treat football injuries.... BMW could soon implement digital twins at all facilities.

Frank Bachmann, the plant director in Regensburg, says that the advantages of digital twins will only be fully realized when every factory is digitized in a standard way. "We need these processes of digital twins everywhere," he says.
The technology "raises questions about privacy and cybersecurity," Time warns. "Many of these digital twins are made possible by a multitude of sensors that track real-world data and movement.

"Workers at factories with digital twins may find their every movement followed; the hacker of a digital twin could gain frighteningly precise knowledge about a complex proprietary system."

The International Space Station's operations have been extended through 2030, NASA announced on Friday. "Though it was never in doubt that the U.S. would continue its near-term commitment to the ISS," reports Engadget, "NASA's announcement comes amid heightened tensions with Russia, one of several nations sharing access to the Space Station. 2021 also saw Russia deepen its cooperation in space with China, another US adversary, as The New York Times noted in June."

NASA's announcement emphasized it would continue work with the space agencies of Europe, Japan, Canada, and Russia "to enable continuation of the groundbreaking research being conducted in this unique orbiting laboratory through the rest of this decade." From NASA.gov: "The International Space Station is a beacon of peaceful international scientific collaboration and for more than 20 years has returned enormous scientific, educational, and technological developments to benefit humanity...." said NASA Administrator Bill Nelson. "As more and more nations are active in space, it's more important than ever that the United States continues to lead the world in growing international alliances and modeling rules and norms for the peaceful and responsible use of space...." Nearly 110 countries and areas have participated in activities aboard the station, including more than 1,500,000 students per year in STEM activities.

Instruments aboard the ISS, used in concert with free-flying instruments in other orbits, help us measure the stresses of drought and the health of forests to enable improved understanding of the interaction of carbon and climate at different time scales. Operating these and other climate-related instruments through the end of the decade will greatly increase our understanding of the climate cycle.

Extending operations through 2030 will continue another productive decade of research advancement and enable a seamless transition of capabilities in low-Earth orbit to one or more commercially owned and operated destinations in the late 2020s. The decision to extend operations and NASA's recent awards to develop commercial space stations together ensure uninterrupted, continuous human presence and capabilities; both are critical facets of NASA's International Space Station transition plan.
NASA's announcement also points out that the Space station has hosted "more than 3,000 research investigations from over 4,200 researchers across the world."

"China has formally approved three missions targeting the south pole of the moon, with the first to launch around 2024..." reports Space.com, "each with different goals and an array of spacecraft." The trio make up the so-called fourth phase for the Chinese lunar exploration program, which most recently landed on the moon last December with a sample-return mission dubbed Chang'e 5. Wu Yanhua, deputy head of the China National Space Administration (CNSA), told China Central Television (CCTV) in a recent interview that the three missions had been approved.

Chang'e 7 will be the first to launch; Wu did not provide a timeline, but previous reporting indicates a hoped-for launch around 2024, with the mission to include an orbiter, a relay satellite, a lander, a rover and a "mini flying craft" designed to seek out evidence of ice at the lunar south pole. The various component spacecraft will carry a range of science instruments including cameras, a radar instrument, an infrared spectrum mineral imager, a thermometer, a seismograph and a water-molecule analyzer; the mission will tackle goals including remote sensing, identifying resources and conducting a comprehensive study of the lunar environment...

Chang'e 8 will launch later this decade and will be a step toward establishing a joint International Lunar Research Station (ILRS) with Russia and potentially other partners. The mission is expected to test technology for using local resources and manufacturing with 3D printing, according to earlier Chinese press statements.... The ILRS plan includes development of a robotic base which can be later expanded to allow astronauts to make long-term stays on the lunar surface in the 2030s.
China had previously scheduled their lunar research station for the year 2035, reports the South China Morning Post. The newspaper cites concerns from Zhang Chongfeng, deputy chief designer of China's manned space programme, that America's space program might ultimately seize common land on the moon. The US government and Nasa have proposed the Artemis Accords to set rules for future lunar activities. Already signed by more than a dozen US allies, the accords allow governments or private companies to protect their facilities or "heritage sites" by setting up safety zones that forbid the entry of others. China and Russia are opposed to the accords because this challenges the existing international protocols including the UN's Moon Agreement, which states that the moon belongs to the entire human race, not a certain party, according to Zhang.

But to effectively counter the US on the moon, China would have to "take some forward-looking measures and deploy them ahead of schedule", he said in a paper published in domestic peer-reviewed journal Aerospace Shanghai in June... Instead of building an orbiting "gateway", China would directly put a nuclear-powered research station on the moon. The unmanned facility would allow visiting Chinese astronauts to stay on the moon for as long as their American peers but only at a fraction of the cost. To counter the US territorial claims, China would also deploy a mobile station. This moon base on wheels would be able to roam freely on the lunar surface for over 1,000km, and the use of artificial intelligence technology would mean astronauts need not be present for its operation.

And, unlike the American programme, which focuses on surface activities, China would pay a great deal of attention to the exploration of caves, which could provide a natural shelter for the construction of permanent settlements.

"With the successful extension of Webb's second sunshield mid-boom, the observatory has passed another critical deployment milestone," NASA announced Friday, adding that the sunshield "now resembles its full, kite-shaped form in space..." The completion of the sunshield cover and mid-boom deployments over the past two days marks a critical milestone for Webb: all 107 membrane release devices associated with the sunshield deployment — every single one of which had to work in order for the sunshield to deploy — have now successfully released. Webb has 178 of these 'non-explosive actuators' in all; 107 were used to keep the sunshield safe and folded prior to deployment...

While the deployments took longer than expected today, that was due to the operations team moving forward with caution and according to the protocols they laid out for dealing with unpredictable situations...

The two mid-boom arms are now locked in their final position. They will hold the sunshield membranes in their proper place, as the team turns to the final stage in the sunshield's deployment: tensioning. In the coming days, the team will separate and then individually tension each of the five sunshield layers, stretching them into their final, taut shape. This will create space between the membranes to allow heat to radiate out, making each successive layer of the sunshield cooler than the one below... Sunshield tensioning will take at least two days but may take longer, due to the complexity of the process and the flexibility built into the timeline.
Universe Today shares a video showing the complexity of the sunshield operation. Long-time Slashdot reader necro81 writes that "Unlike other nail-biting JWST events like the rocket launch, something of this size and complexity has never been attempted in space.

"After this, the telescope's optics will be in the shade forevermore, and can begin cooling to the frigid operating temperature needed to detect infrared light."

NPR reports: In late November, more than 110 people gathered at a crowded Christmas party at a restaurant in Oslo. Most of the guests were fully vaccinated. One had returned from South Africa just a few days earlier and was unknowingly carrying the omicron variant of SARS-CoV-2. Ultimately, about 70% of the partygoers were infected. Scientists who traced this super spreader event concluded it was evidence that omicron was "highly transmissible" among fully-vaccinated adults. Just over a month later, omicron's speedy worldwide ascent now makes it abundantly clear that the party wasn't an isolated example. In country after country, the new variant has outcompeted its predecessor, the delta variant -- with one case of omicron sparking at least three other new infections on average. Cases have soared to record highs in parts of Europe and now the U.S., where about half a million new infections have been recorded in a single day. "This is a game-changing virus, especially in the vaccinated population where people have had a level of invincibility," says Sumit Chanda, a professor in the Department of Immunology and Microbiology at Scripps Research.

Indeed, in a world where vaccinations and infections have built up immunity, other variants were having trouble gaining a foothold. Yet omicron is thriving. "This changes the calculus for everybody," says Chanda. And so scientists are trying to figure out: What accounts for omicron's lightning quick spread? While it's still early, they're starting to piece together why the new variant is so contagious -- and whether that means old assumptions about how to stay safe need to be revamped. [...] The variant's many mutations on the spike protein allow it to infect human cells more efficiently than previous variants could, leaving many more people again vulnerable. Because of that, "immune escape" alone could be the major reason why the variant looks so contagious compared to delta, which was already highly transmissible.

In fact, omicron has been spreading at a pace that's comparable to how fast the original strain of the coronavirus spread at the very beginning of the pandemic despite the world's newfound levels of immunity. "The playing field for the virus right now is quite different than it was in the early days," says Dr. Joshua Schiffer, an infectious disease researcher at Fred Hutchinson Cancer Research Center. "The majority of variants we've seen to date couldn't survive in this immune environment." Even delta was essentially at a "tie," he says, where it was persisting, but "not growing very rapidly or decreasing very rapidly." A new study from Denmark suggests that much of the variant's dominance comes down to its ability to evade the body's immune defenses. Researchers compared the spread of omicron and delta among members of the same household and concluded that omicron is about 2.7 to 3.7 times more infectious than the delta variant among vaccinated and boosted individuals.

A spate of new studies on lab animals and human tissues are providing the first indication of why the Omicron variant causes milder disease than previous versions of the coronavirus. From a report: In studies on mice and hamsters, Omicron produced less damaging infections, often limited largely to the upper airway: the nose, throat and windpipe. The variant did much less harm to the lungs, where previous variants would often cause scarring and serious breathing difficulty. "It's fair to say that the idea of a disease that manifests itself primarily in the upper respiratory system is emerging," said Roland Eils, a computational biologist at the Berlin Institute of Health, who has studied how coronaviruses infect the airway. In November, when the first report on the Omicron variant came out of South Africa, scientists could only guess at how it might behave differently from earlier forms of the virus. All they knew was that it had a distinctive and alarming combination of more than 50 genetic mutations.

Previous research had shown that some of these mutations enabled coronaviruses to grab onto cells more tightly. Others allowed the virus to evade antibodies, which serve as an early line of defense against infection. But how the new variant might behave inside of the body was a mystery. "You can't predict the behavior of virus from just the mutations," said Ravindra Gupta, a virologist at the University of Cambridge. Over the past month, more than a dozen research groups, including Dr. Gupta's, have been observing the new pathogen in the lab, infecting cells in Petri dishes with Omicron and spraying the virus into the noses of animals. As they worked, Omicron surged across the planet, readily infecting even people who were vaccinated or had recovered from infections. But as cases skyrocketed, hospitalizations increased only modestly. Early studies of patients suggested that Omicron was less likely to cause severe illness than other variants, especially in vaccinated people. Still, those findings came with a lot of caveats.

fahrbot-bot writes: The world is full of beautiful equations, numbers and calculations. From counting beads as toddlers to managing finances as adults, we use math every day. But scientists often go beyond these quotidian forms of counting, to measure, weigh and tally far stranger things in the universe. From the number of bubbles in a typical glass of beer to the weight of all the coronavirus particles circulating in the world, LiveScience notes the 10 weird things scientists calculated in 2021.

1. Number of bubbles in a half-pint glass of beer: up to 2 million bubbles, about twice as many as Champagne.
2. Weight of all SARS-CoV-2 particles: between 0.22 and 22 pounds (0.1 and 10 kilograms).
3. Counted African elephants from space for the first time -- Earth elephants (using satellites and AI) not Space Elephants.
4. Acceleration of a finger snap: maximal rotational velocities of 7,800 deg/s and a maximal rotational acceleration of 1.6 million deg/s squared -- in seven milliseconds, more than 20 times faster than the blink of an eye, which takes more than 150 milliseconds.
5. Calculated pi to 62.8 trillion decimal places.
6. Updated the "friendship paradox" equations.
7. Theoretical number and mass of all Black Holes: about 1% of all ordinary matter (not dark matter) in the universe.
8. How long would it take to walk around the moon? At 4 hours a day, it would take about 547 Earth days, or about 1.5 years.
9. How many active satellites currently orbit the planet? As of September 2021, there were around 7,500 active satellites in low Earth orbit.
10. The "absolute limit" on the human life span: probably 120 to 150 years.

Thirty feet underground and a stone's throw from Stanford University, scientists are putting the finishing touches on a laser that could fundamentally change the way they study the building blocks of the universe. CNET reports: When completed next year, the Linac Coherent Light Source II, or the LCLS-II , will be the second world-class X-ray laser at the Department of Energy's SLAC National Accelerator Laboratory. CNET was given the rare opportunity to film inside the more than 2-mile long tunnel ahead of the new laser's launch. The first LCLS, in operation since 2009, creates a beam capable of 120 light pulses per second. The LCLS-II will be capable of up to 1 million pulses per second, and a beam 10,000 times brighter than its predecessor.

You can think of the LCLS as being like a microscope with atomic resolution. At its core it is a particle accelerator, a device that speeds up charged particles and channels them into a beam. That beam is then run through a series of alternating magnets (a device called an undulator) to produce X-rays. Scientists can use those X-rays to create what they call molecular movies. These are snapshots of atoms and molecules in motion, captured within a few quadrillionths of a second, and strung together like a film. Scientists across nearly every scientific field have come from all over the world to run their experiments with the LCLS. Among other things, their molecular movies have shown chemical reactions as they happened, demonstrated the behavior of atoms inside stars, and produced live snapshots detailing the process of photosynthesis.

Though both lasers accelerate electrons to nearly the speed of light, they'll each do it differently. The LCLS's accelerator pushes the electrons down a copper pipe that operates at room temperature, designed to be activated only in short bursts. But the LCLS-II is designed to run continuously, which means it generates massive amounts of heat. A copper cavity would absorb too much of that heat. That's why engineers turned to a new superconducting accelerator, composed of dozens of 40-foot-long devices called cryomodules designed to run at two degrees above absolute zero (-456 degrees Fahrenheit). They're kept at operating temperature by a massive cryogenics plant above ground.

[T]he LCLS-II will allow SLAC scientists answer questions they've been trying to solve for years. "How does energy transfer happen inside molecular systems? How does charge transfer happen? Once we understand some of these principles, we can start to apply them to understand how we can do artificial photosynthesis, how can we build better solar cells." Scientists at SLAC hope to produce their first electron beam with the LCLS-II in January, followed by their first X-ray in the summer, which they'll refer to as their first "big light" event.

A sugar additive used in several foods could have helped spread a seriously dangerous superbug around the US, according to a 2018 study. ScienceAlert reports: The finger of blame is pointed squarely at the sugar trehalose, found in foods such as nutrition bars and chewing gum. If the findings are confirmed, it's a stark warning that even apparently harmless additives have the potential to cause health issues when introduced to our food supply. In this case, trehalose is being linked with the rise of two strains of the bacterium Clostridium difficile, capable of causing diarrhea, colitis, organ failure, and even death. The swift rise of the antibiotic-resistant bug has become a huge problem for hospitals in recent years, and the timing matches up with the arrival of trehalose.

"In 2000, trehalose was approved as a food additive in the United States for a number of foods from sushi and vegetables to ice cream," said one of the researchers, Robert Britton from the Baylor College of Medicine in Texas, back in January 2018. "About three years later the reports of outbreaks with these lineages started to increase. Other factors may also contribute, but we think that trehalose is a key trigger."

The C. difficile lineages Britton is referring to are RT027 and RT078. When the researchers analysed the genomes of these two strains, they found DNA sequences that enabled them to feed off low doses of trehalose sugar very efficiently. In fact, these particular bacteria need about 1,000 times less trehalose to live off than other varieties of C. difficile, thanks to their genetic make-up. [...] It's still not certain that trehalose has contributed to the rise of C. difficile, but the study results and the timing of its approval as an additive are pretty compelling. More research will now be needed to confirm the link. According to figures from the CDC, "C. difficile was responsible for half a million infections across the year and 29,000 deaths within the first 30 days of diagnosis," adds ScienceAlert.

The findings were published in the journal Nature.

The experimental process of removing carbon dioxide from the atmosphere and storing it in oceans could help limit global warming to 1.5 degrees Celsius, explain Romany Webb and Michael B. Gerrard, both of the Sabin Center for Climate Change Law at Columbia Law School. Overcoming challenges presented by this treatment will need coordination with all stakeholders, including research scientists, investors, and environmental groups, they say. An anonymous reader quotes a report from Bloomberg Law: At last month's climate conference in Glasgow, U.N. Secretary General Antonio Guterres declared that the global goal of limiting warming to 1.5 degrees Celsius was still alive, but "on life support." Carbon dioxide removal (CDR) -- the process of drawing carbon dioxide out of the atmosphere and storing it on land or in the oceans -- could be part of the medicine needed to bring it back to life. But, like all experimental treatments, its use presents a range of challenges. Overcoming them will require a coordinated effort by a wide range of stakeholders, from research scientists and investors to policymakers and lawyers to environmental and community groups. So far, no CDR techniques have been deployed at a large scale, and many require significantly more research before that can happen.

A new report from the National Academies of Sciences identifies over $1 billion worth of "priority research" that will be needed over the next 10 years to better assess the feasibility and impacts of key ocean CDR techniques. That includes $125 million for so-called "foundational research" on legal, policy, social science, and related issues. [...] On the legal side, there is significant uncertainty as to how different CDR techniques, particularly ocean-based techniques, will be regulated. Because the oceans form part of the global commons, ocean-based activities are subject to a large body of international law. But there is currently no comprehensive international legal framework specific to ocean CDR.

There are no U.S. federal laws dealing specifically with ocean CDR. Unless and until that changes, projects will end up being regulated under general environmental laws that were developed with other activities in mind, and so may be poorly suited to ocean CDR. We've documented some of the potential problems in two recent reports on the laws governing ocean alkalinization and seaweed cultivation for the purposes of CDR. As recognized in the National Academies report, developing a "clear and consistent legal framework for ocean CDR is essential to facilitate research and (if deemed appropriate) full-scale deployment, while also ensuring that projects are conducted in a safe and environmentally sound manner."It is vital that framework be developed with input from all stakeholders -- scientists, entrepreneurs, governments, NGOs, environmentalists, indigenous peoples, coastal communities, and other potentially impacted groups. Those same groups must continue to be engaged as projects are developed and deployed. [...] Further engagement and coordination with the full range of stakeholders are important to ensure safe and responsible CDR development and deployment. Without that, our hopes of limiting warming to 1.5 degrees Celsius may well be dead and buried.

Two dozen theologians participated in a program funded partially by NASA to research how humans may react to news that intelligent life exists on other planets, according to one religious scholar who says he was recruited. From a report: The Rev. Dr. Andrew Davison, of the University of Cambridge, told the Times UK in a recent interview that he was among 23 other theologians in a NASA-sponsored program at the Center for Theological Inquiry at Princeton University from 2016 to 2017. Davison said he and his colleagues examined how each of the world's major religions would likely respond if they were made aware of the existence of aliens. His own work focused on the connection between astrobiology and Christian theology. Will Storrar, director of the CTI, said NASA wanted to see "serious scholarship being published in books and journals" addressing the "profound wonder and mystery and implication of finding microbial life on another planet," the Times reported.

[...] NASA's Astrobiology program provided partial funding through a grant to the CTI in 2015, with the agency-funded portion of the project concluding in 2017, a NASA spokesperson confirmed to Changing America. NASA was not directly involved in the selection of researchers for the study.