The Independent reports that the UK's National Health System is experiencing a major outage "expected to last for more than three weeks" after a third-party supplying the NHS's "CareNotes" software was hit by ransomware.

Unfortunately, this leaves doctors unable to see their notes on patients, and the mental health trusts that provide care "across the country will be left unable to access patient notes for weeks, and possibly months." Oxford Health NHS Foundation Trust has declared a critical incident over the outage, which is believed to affect dozens of trusts, and has told staff it is putting emergency plans in place. One NHS trust chief said the situation could possibly last for "months" with several mental health trusts, and there was concern among leaders that the problem is not being prioritised.

In an email to staff, Oxford Health NHS Foundation Trust chief executive Nick Broughton, said: "The cyberattack targeted systems used to refer patients for care, including ambulances being dispatched, out of hours appointment bookings, triage, out of hours care, emergency prescriptions and safety alerts. It also targeted the finance system used by the trust.... An NHS director said: "The whole thing is down. It's really alarming...we're carrying a lot of risk as a result of it because you can't get records and details of assessments, prescribing, key observations, medical mental health act observations. You can't see any of it...Staff are going to have to write everything down and input it later."

They added: "There is increased risk to patients. We're finding it hard to discharge people, for example to housing providers, because we can't access records."
"'Weeks' is an unreasonable period," argues Slashdot reader Bruce66423, wondering why it couldn't be resolved with a seemingly simple restore from backups?

And Alan Woodward, a professor of cybersecurity at Surrey University, warns the Guardian that "Even if it was ransomware ... that doesn't mean data was not stolen."

Australia's public broadcaster interviewed a virologist who "played a key role in mapping the evolution of COVID-19" (and was also "the first person to release the sequence of SARS-CoV-2 to the world.")

But interestingly, this Australian virologist also visited the Wuhan market in 2014, "and recognised the risk of virus transmission between animals and humans and suggested taking some samples." "While I was there, I noticed there were these live wildlife for sale, particularly raccoon dogs and ... muskrats" he said. "I took the photographs because I thought to myself: 'God, that's, that's not quite right'." Raccoon dogs had been associated with the emergence of a different coronavirus outbreak, SARS-CoV-1, in 2002-04, which became known worldwide as the SARS virus.

Even in 2014, Professor Holmes believed the market could become a site of virus transmission between animals and humans. The monitoring that Professor Holmes suggested never took place but, in the early days of COVID-19, he was still convinced that a market like the one in Wuhan was the logical origin of the virus. "They are the kind of engine room of [this sort] of disease emergence ... because what you're doing is you're putting humans and wildlife in close proximity to each other," he said.
The professor also describes the theory that the virus some how leaked from a Chinese lab as "horrendous, blame-game finger-pointing," noting that the nearest lab is miles away. And he cites other reasons the market is where the virus originated: Aside from the geographic clustering, he also points to the fact that two different strands emerged almost simultaneously in humans, something that is much more likely if the virus had already been mutating in animals. "They're sufficiently far apart that they were probably independent jumps.

"It means there was a pool of infected animals in the market and it's mutated amongst them before it jumped to humans."

All of this has led Professor Holmes to conclude that the question of how COVID-19 emerged is settled. "I'm extremely confident that the virus is not from a laboratory. I think that's just a nonsensical theory," he said. Detailed mapping of where samples were detected inside the Huanan seafood wholesale market allowed Professor Holmes and his colleagues to even pinpoint to a few square metres where COVID-19 was likely to have jumped between humans and animals.

"It's extraordinary," he said. "And I took a photo in 2014 of one of the stalls that was the most positively tested in the whole market."

An anonymous reader quotes a report from The New York Times: Polio has been detected in New York City wastewater, suggesting that the virus that causes the disease is probably circulating in the city, the health authorities said on Friday. The announcement came three weeks after a man in Rockland County, N.Y., north of the city, was diagnosed with polio thatleft him with paralysis. Health officials fear that the detection of polio in New York City's wastewater could precede other cases of paralytic polio. The spread of the virus poses a risk to unvaccinated people, but a three-dose course of the vaccine provides at least 99 percent protection.

Most adults in the United Stateswere vaccinated against polio as children. In New York City, the overall rate of polio vaccination among children 5 and under is 86 percent. Still, insome city ZIP codes, fewer thantwo-thirds of children in that group have received a full regimen, a figure that worries health officials. (The citywide vaccination rate dipped amid the pandemic, as visits to pediatricians were postponed.) Although many people who become infected with polio do not develop symptoms, about 4 percent will get viral meningitis and about 1 in 200 will become paralyzed, according to the health authorities. Parents of children who have not yet been fully vaccinated should see that they are immediately, officials said. "While the polio virus had previously been detected in wastewater samples in Rockland and neighboring Orange Counties, the announcement on Friday was the first sign it had been found in New York City," adds the report. "The city's health department did not provide details about where exactly in the five boroughs polio had been found in the wastewater, nor did officials provide dates for when the virus was detected or say how many samples had tested positive."

Further reading: Vaccine-Derived Polio Is On the Rise

An anonymous reader shares a report: Physical labour is exhausting. A long run or a hard day's sweat depletes the body's energy stores, resulting in a sense of fatigue. Mental labour can also be exhausting. Even resisting that last glistening chocolate-chip cookie after a long day at a consuming desk job is difficult. Cognitive control, the umbrella term encompassing mental exertion, self-control and willpower, also fades with effort. But unlike the mechanism of physical fatigue, the cause of cognitive fatigue has been poorly understood. Previous accounts were incomplete. One of the most widely known, the biological one, draws from what is known about muscular fatigue. It posits that exerting cognitive control uses up energy in the form of glucose. At the end of a day spent intensely cogitating, the brain is metaphorically running on fumes. The problem with this version of events is that the energy cost associated with thinking is minimal. One analysis of previous studies suggests that cognitively overworked and "depleted" brains use less than one-tenth of a Tic-Tac's worth of additional glucose.

If cognitive fatigue is not caused by a lack of energy, then what explains it? A team of scientists led by Antonius Wiehler of Pitie-Salpetriere University Hospital, in Paris, looked at things from what is termed a neurometabolic point of view. They hypothesise that cognitive fatigue results from an accumulation of a certain chemical in the region of the brain underpinning control. That substance, glutamate, is an excitatory neurotransmitter that abounds in the central nervous systems of mammals and plays a role in a multitude of activities, such as learning, memory and the sleep-wake cycle. In other words, cognitive work results in chemical changes in the brain, which present behaviourally as fatigue. This, therefore, is a signal to stop working in order to restore balance to the brain. In their new paper in Current Biology, the researchers describe an experiment they undertook to explain how all this happens.

An anonymous reader quotes a report from Phys.Org: In a new University of California, Irvine-led study, researchers define how the circadian clock influences cell growth, metabolism and tumor progression. Their research also reveals how disruption of the circadian clock impacts genome stability and mutations that can further drive critical tumor-promoting pathways in the intestine. In this study, researchers found that both genetic disruption and environmental disruption of the circadian clock contribute to the mutation of the adenomatous polyposis coli (APC) tumor suppressor, which is found in the vast majority of human colorectal cancers (CRC). APC point mutations, deletions, and loss of heterozygosity (LOH) events have been reported in approximately 80 percent of human CRC cases, and it is these mutations that drive the initiation of intestinal adenoma development.

"As a society, we are exposed to several environmental factors that influence our biological clock, including night shift work, extended light exposure, changes in sleep/wake cycles and altered feeding behavior," said Selma Masri, Ph.D., assistant professor of biological chemistry at UCI School of Medicine. "Strikingly, we have seen an alarming increase in several young-onset cancers, including colorectal cancer. The underlying cause of this increased incidence of cancer in adults in their 20s and 30s remains undefined. However, based on our findings, we now believe that disruption of the circadian clock plays an important role." The study has been published in the journal Science Advances.

After more than 50 years, molten salt nuclear reactors might be making a comeback. The US Department of Energy (DoE) has tapped Los Alamos National Laboratory (LANL) to lead a $9.25 million study into the structural properties and materials necessary to build them at scale. The Register reports: "The US needs projects like this one to advance nuclear technologies and help us achieve the Biden-Harris administration's goals of clean energy by 2035 and a net-zero economy by 2050," said Asmeret Asefaw Berhe, director of the office of science, in a statement. The study, conducted as part of the Scientific Discovery though Advanced Computing (SciDAC) program, seeks to gain a better understanding of the relationship between corrosion and irradiation effects at the atomic scale in metals exposed to molten salt reactors through simulation.

This isn't the first time the DoE has explored this reactor tech. In the middle of last century, Oak Ridge National Laboratory (ORNL) took the lessons learned from the Aircraft Reactor experiment to build a functional nuclear aircraft power source and began construction of a molten salt test reactor. The experiments, conducted between 1957 and 1969, utilized a mixture of lithium, beryllium, zirconium, and uranium fluoride salts. Cooling was also achieved using a fluoride salt mixture, but it lacked the uranium and zirconium found in the fuel. The experiments proved promising, as molten salt reactors were generally smaller and considered safer compared to the pressurized water reactors still used today. But both proved too heavy for powered flight or materials design. Because cooling was achieved by circulating molten salt through a heat exchanger as opposed to water, the risk of a steam explosion is effectively nonexistent. However, as the Oak Ridge National Laboratory found during the Molten Salt Reactor Experiment, fluoride salts are incredibly corrosive and required hardened materials to safely contain them. "ORNL's Molten Salt Reactor Experiment utilized specialized materials fabricated from Hastelloy-N -- a nickel-molybdenum alloy developed by the lab with a high resistance to corrosion even at high temperatures," adds the reports. "The research program announced this week will revisit the material choices and examine a variety of metals using higher-performance compute resources to simulate how they'll perform at scale in these reactors."

An anonymous reader quotes a report from Phys.Org: A new study corrects an important error in the 3D mathematical space developed by the Nobel Prize-winning physicist Erwin Schrodinger and others, and used by scientists and industry for more than 100 years to describe how your eye distinguishes one color from another. The research has the potential to boost scientific data visualizations, improve TVs and recalibrate the textile and paint industries. [...] "Our original idea was to develop algorithms to automatically improve color maps for data visualization, to make them easier to understand and interpret," [said Roxana Bujack, a computer scientist with a background in mathematics who creates scientific visualizations at Los Alamos National Laboratory and lead author of the paper]. So the team was surprised when they discovered they were the first to determine that the longstanding application of Riemannian geometry, which allows generalizing straight lines to curved surfaces, didn't work.

To create industry standards, a precise mathematical model of perceived color space is needed. First attempts used Euclidean spaces -- the familiar geometry taught in many high schools; more advanced models used Riemannian geometry. The models plot red, green and blue in the 3D space. Those are the colors registered most strongly by light-detecting cones on our retinas, and -- not surprisingly -- the colors that blend to create all the images on your RGB computer screen. In the study, which blends psychology, biology and mathematics, Bujack and her colleagues discovered that using Riemannian geometry overestimates the perception of large color differences. That's because people perceive a big difference in color to be less than the sum you would get if you added up small differences in color that lie between two widely separated shades. Riemannian geometry cannot account for this effect. "We didn't expect this, and we don't know the exact geometry of this new color space yet," Bujack said. "We might be able to think of it normally but with an added dampening or weighing function that pulls long distances in, making them shorter. But we can't prove it yet."

The findings appear in the journal Proceedings of the National Academy of Science.

An anonymous reader quotes a report from The Guardian: China has overtaken the US as the world leader in both scientific research output and "high impact" studies, according to a report published by Japan's science and technology ministry. The report, which was published by Japan's National Institute of Science and Technology Policy (NISTP) on Tuesday, found that China now publishes the highest number of scientific research papers yearly, followed by the US and Germany. The figures were based on yearly averages between 2018 and 2020, and drawn from data compiled by the analytics firm Clarivate.

The Japanese NISTP report also found that Chinese research comprised 27.2% of the world's top 1% most frequently cited papers. The number of citations a research paper receives is a commonly used metric in academia. The more times a study is cited in subsequent papers by other researchers, the greater its "citation impact." The US accounted for 24.9% of the top 1% most highly cited research studies, while UK research was third at 5.5%. China published a yearly average of 407,181 scientific papers, pulling ahead of the US's 293,434 journal articles and accounting for 23.4% of the world's research output, the report found. China accounted for a high proportion of research into materials science, chemistry, engineering and mathematics, while US researchers were more prolific in research into clinical medicine, basic life sciences and physics. "China is one of the top countries in the world in terms of both the quantity and quality of scientific papers," Shinichi Kuroki of the Japan Science and Technology Agency told Nikkei Asia. "In order to become the true global leader, it will need to continue producing internationally recognized research."

The nation's top public health agency relaxed its COVID-19 guidelines Thursday, dropping the recommendation that Americans quarantine themselves if they come into close contact with an infected person. The Centers for Disease Control and Prevention also said people no longer need to stay at least 6 feet away from others. The Associated Press reports: The changes, which come more than 2 1/2 years after the start of the pandemic, are driven by a recognition that an estimated 95% of Americans 16 and older have acquired some level of immunity, either from being vaccinated or infected, agency officials said. "The current conditions of this pandemic are very different from those of the last two years," said the CDC's Greta Massetti, an author of the guidelines.

Perhaps the biggest education-related change is the end of the recommendation that schools do routine daily testing, although that practice can be reinstated in certain situations during a surge in infections, officials said. The CDC also dropped a "test-to-stay" recommendation, which said students exposed to COVID-19 could regularly test -- instead of quarantining at home -- to keep attending school. With no quarantine recommendation anymore, the testing option disappeared too. Masks continue to be recommended only in areas where community transmission is deemed high, or if a person is considered at high risk of severe illness.

A study found that while some fireflies shrugged off light pollution, members of other species failed to mate even when males and females could find each other. From a report: As dusk deepens the shadow at the forest's edge, a tiny beacon lights up the gloom. Soon, the twilight is full of drifting lights, each winking a message in peculiar semaphore: "Male seeks female for brief union." This courtship plays out on summer nights the world over among beetles of the Lampyridae family, commonly known as fireflies. The darkness in which fireflies have always pursued their liaisons, however, has been breached by the glare of artificial lights. Humans' love affair with illumination has led to much of the Earth's habitable surfaces suffering light pollution at night. In recent years, scientists who study fireflies have heard from people who are worried that the insects may be in decline, said Avalon Owens, an entomologist at Tufts University. "There's this sense of doom. They seem to not be in places where they used to be," she said.

So little is known about how fireflies live that it is hard to assess whether they are in danger -- and if so, why, said Dr. Owens. But in a study published Wednesday in the journal Royal Society Open Science, she and Sara Lewis, a professor of biology at Tufts University, shone some light on how fireflies respond to artificial illumination. Experiments in forests and fields as well as the lab showed that while some North American fireflies would mate with wild abandon, regardless of illumination, others did not complete a single successful mating under the glare of the lights. Fireflies seem to rely primarily on flashes of light to find each other, which means light pollution could threaten their ability to see mates. In the four common species the study examines, the females hide on the ground and observe as males wander the skies. When a female responds to a male's flashing with her own, the two enter into a dialogue that can end in a meeting, and eventually mating.

An anonymous reader shares a report: Technology to build cleaner, more efficient air conditioners does exist. Two major AC manufacturers, Daikin and Gree Electric Appliances, shared the top award at last year's Global Cooling Prize, an international competition focused on designing climate-friendly AC tech. Both companies created ACs with higher internal performance that used less environmentally damaging refrigerants; the new units could reduce their impact on the climate by five times. [...] Another strategy is to double down on heat pumps, which are air conditioners that also work in reverse, using vapor compression to absorb and move heat into a home, instead of releasing it outside. Heat pumps usually cost several thousand dollars, though the Inflation Reduction Act includes a proposal for a significant heat pump rebate, and President Joe Biden has invoked the Defense Production Act to ramp up production.

Experts have argued installing heat pumps is critical to another important climate goal: transitioning away from fossil fuel-powered furnaces, which are an even bigger source of emissions than cooling. The holy grail of HVAC would be a heat pump that could provide both heating and cooling but isn't dependent on vapor compression. [...] Another challenge, though, is that heat pumps are not the easiest appliance to install, especially for renters, who don't necessarily have the money or ability to invest in bulky HVAC systems. To address this problem, a company called Gradient has designed a heat pump that easily slides over a windowsill -- it doesn't block light -- and currently uses a refrigerant called R32, which is supposed to have a (comparatively) low global warming potential. Gradient recently won a contract to install its units in New York City public housing.

The rapid warming of the Arctic, a definitive sign of climate change, is occurring even faster than previously described, researchers in Finland said Thursday. From a report: Over the past four decades the region has been heating up four times faster than the global average, not the commonly reported two to three times. And some parts of the region, notably the Barents Sea north of Norway and Russia, are warming up to seven times faster, they said. The result is faster melting of the Greenland ice sheet, which leads to greater sea-level rise. But it also affects atmospheric circulation in North America and elsewhere, with impacts on weather like extreme rainfall and heat waves, although some of the impacts are a subject of debate among scientists.

While scientists have long known that average temperatures in the Arctic are increasing faster than the rest of the planet, the rate has been a source of confusion. Studies and news accounts have estimated it is two to three times faster than the global average. Mika Rantanen, a researcher at the Finnish Meteorological Institute in Helsinki, said he and his colleagues decided to look at the issue in the summer of 2020, when intense heat waves in the Siberian Arctic drew a lot of attention. The new findings are bolstered by those of another recent study, led by scientists at Los Alamos National Laboratory, which found similar rates of warming, although over a different time span.

Researchers have begun tracking a newly identified virus in China, with dozens of cases recorded so far. From a report: The novel Langya henipavirus (LayV) was first detected in the north-eastern provinces of Shandong and Henan in late 2018 but was only formally identified by scientists last week. The virus was likely transmitted from animals to humans, scientists said, and Taiwan's health authority is now monitoring the spread. The researchers tested wild animals and found LayV viral RNA in more than a quarter of 262 shrews, "a finding that suggests that the shrew may be a natural reservoir." The virus was also detected in 2% of domestic goats and 5% of dogs.

An anonymous reader quotes a report from The Associated Press: Researchers are seeking thousands of volunteers in the U.S. and Europe to test the first potential vaccine against Lyme disease in 20 years -- in hopes of better fighting the tick-borne threat. Lyme is a growing problem, with cases rising and warming weather helping ticks expand their habitat. While a vaccine for dogs has long been available, the only Lyme vaccine for humans was pulled off the U.S. market in 2002 from lack of demand, leaving people to rely on bug spray and tick checks. Now Pfizer and French biotech Valneva are aiming to avoid previous pitfalls in developing a new vaccine to protect both adults and kids as young as 5 from the most common Lyme strains on two continents.

Most vaccines against other diseases work after people are exposed to a germ. The Lyme vaccine offers a different strategy -- working a step earlier to block a tick bite from transmitting the infection, said Dr. Gary Wormser, a Lyme expert at New York Medical College who isn't involved with the new research. How? It targets an "outer surface protein" of the Lyme bacterium called OspA that's present in the tick's gut. It's estimated a tick must feed on someone for about 36 hours before the bacteria spreads to its victim. That delay gives time for antibodies the tick ingests from a vaccinated person's blood to attack the germs right at the source.

In small, early-stage studies, Pfizer and Valneva reported no safety problems and a good immune response. The newest study will test if the vaccine, called VLA15, really protects and is safe. The companies aim to recruit at least 6,000 people in Lyme-prone areas including the Northeast U.S. plus Finland, Germany, the Netherlands, Poland and Sweden. They'll receive three shots, either the vaccine or a placebo, between now and next spring's tick season. A year later, they'll get a single booster dose.

Scientists have discovered that by microwaving fish waste, they can quickly and efficiently create carbon nano-onions (CNOs) -- a unique nanoform of carbon that has applications in energy storage and medicine. This method could be used to make cheaper and more sustainable LEDs in the future. The researchers from Nagoya Institute of Technology in Japan published their findings in Green Chemistry. Smithsonian Magazine reports: CNOs are nanostructures with spherical carbon shells in a concentric layered structure similar to an onion. They have "drawn extensive attention worldwide in terms of energy storage and conversion" because of their "exceptionally high electrical and thermal conductivity, as well as large external surface area," per the paper. They've been used in electronics and for biomedical applications, such as bio-imaging and sensing and drug delivery, write the authors in the study. Though CNOs were first reported in the 1980s, conventional methods of manufacturing them have required high temperatures, a vacuum and a lot of time and energy. Other techniques are expensive and call for complex catalysts or dangerous acidic or basic conditions. This "greatly limits the potential of CNOs," per a statement from Nagoya Institute of Technology.

The newly discovered method requires only one step -- microwave pyrolysis of fish scales extracted from fish waste -- and can be done within ten seconds, per the authors. How exactly the fish scales are converted into CNOs is unclear, though the team thinks it has to do with how collagen in the fish scales can absorb enough microwave radiation to quickly increase in temperature. This leads to pyrolysis, or thermal decomposition, which causes the collagen to break down into gasses. These gasses then support the creation of CNOs. This method is a "straightforward way to convert fish waste into infinitely more useful materials," and the resulting CNOs have a high crystallinity, which gives them "exceptional optical properties," per the statement. They also have high functionalization, which means they're "bonded to other small molecules on their surface," writes Ellen Phiddian for Cosmos. This combination of attributes means the CNOs can glow bright blue.

An anonymous reader quotes a report from Scientific American: Barred from her lab by pandemic restrictions, behavioral ecologist Daniela C. Robler caught local jumping spiders and kept them in clear plastic boxes on her windowsill, planning to test their reactions to 3-D-printed models of predatory spiders. When she came home from dinner one night, though, she noticed something strange. "They were all hanging from the lids of their boxes," says Robler, a postdoctoral researcher at the University of Konstanz in Germany. She had never seen jumping spiders suspended motionless on silk lines like this before. "I had no idea what happened," Robler says. "I thought they were dead." It turns out the jumping spiders were simply asleep -- and that Robler had discovered an alternate sleeping habit of the species Evarcha arcuata, which had been known to build silk sleeping dens in curled-up dead leaves. But the real surprise came when she decided to spy on them all night. [...]

Mostly the spider just hung there. But then her legs started to twitch, and her abdomen and even her silk-producing spinnerets did so as well. Sometimes her legs curled in toward her sternum. With every spider Robler recorded, these odd movements only appeared during distinct bouts that lasted a little more than a minute and occurred periodically throughout the night. "They were just uncontrollably twitching in a way that really looked a lot like when dogs or cats dream and have their little REM phases," she says. [...] Robler and her colleagues wondered if the twitching spiders could be experiencing something like an REM phase of sleep and possibly even having dreams. "We were like, 'Okay, that would be insane,'" she says. Then she thought, "Let's figure it out," and immediately changed her research plans for the spiders.

[...] When Robler recorded 34 sleeping spiderlings, she found that their twitches were accompanied by unmistakable eye-tube movements that did not happen during other phases of sleep. [...] But it is too soon to say for sure that the spiders are experiencing something akin to REM sleep in humans. The researchers first need to confirm the spiders are actually asleep during this phase by showing that they are less responsive to their environment. Robler and her "dream team" of co-authors have already started those tests. And she points out that the leg curling is a particularly striking aspect of the spiders' REM-like phase because that pose is typically only seen in dead spiders. Spiders use hydraulic pressure maintained by muscles to keep their legs extended, and the curling could result from the muscle paralysis that typifies REM sleep. The team's initial findings were published in Proceedings of the National Academy of Sciences USA.

Rainwater almost everywhere on Earth has unsafe levels of "forever chemicals," according to new research. saulgood shares a report: Per- and poly-fluoroalkyl substances (PFAS) are a large family of human-made chemicals that don't occur in nature. They are known as 'forever chemicals' because they don't break down in the environment. They have non-stick or stain repellent properties so can be found in household items like food packaging, electronics, cosmetics and cookware. But now researchers at the University of Stockholm have found them in rainwater in most locations on the planet -- including Antarctica. There is no safe space to escape them. Safe guideline levels for some of these forever chemicals have dropped dramatically over the last two decades due to new insights into their toxicity. "There has been an astounding decline in guideline values for PFAS in drinking water in the last 20 years," says Ian Cousins, lead author of the study and professor at the Department of Environmental Science, Stockholm University. For one well-known substance, the "cancer-causing perfluorooctanoic acid (PFOA)," water guideline values have declined by 37.5 million times in the US.

India's new rocket launched for the first time on Saturday night (Aug. 6) but failed to deliver its satellite payloads into their intended orbit due to a sensor issue. Space.com reports: The 112-foot-tall (34 meters) Small Satellite Launch Vehicle (SSLV) lifted off from Satish Dhawan Space Centre on India's southeastern coast on Saturday at 11:48 p.m. EDT (0348 GMT and 9:18 a.m. India Standard Time on Sunday, Aug. 7) with two satellites onboard. The rocket's three solid-fueled stages performed well, but its fourth and final stage, a liquid-fueled "velocity trimming module" (VTM), hit a snag: Indian Space Research Organisation (ISRO) officials reported a loss of data from the rocket and, just over five hours after liftoff, ISRO announced the mission had failed.

"The entire vehicle performance was very good" at the start, but ultimately left the two satellites in the wrong orbit, ISRO Chairman S. Somanath said in a video statement after the launch. "The satellites were placed in an elliptical orbit in place of a circular orbit." Instead of placing the satellites in a circular orbit 221 miles (356 kilometers) above Earth, the rocket left them in an orbit that ranged from 221 miles to as close as 47 miles (76 km). That orbit was not stable, and the satellites have "already come down, and they are not usable," Somanath said. ISRO officials said on Twitter that a sensor failure that was not detected in time to switch to a "salvage action" caused the orbit issue. An investigation into the failure is planned.

David Glowacki, an artist and computational molecular physicist, has created a VR experience called Isness-D that aims to recapture a transcendence experience he had when he fell in the mountains fifteen years ago. "[O]n four key indicators used in studies of psychedelics, the program showed the same effect as a medium dose of LSD or psilocybin (the main psychoactive component of 'magic' mushrooms)," reports MIT Technology Review. From the report: Isness-D is designed for groups of four to five people based anywhere in the world. Each participant is represented as a diffuse cloud of smoke with a ball of light right about where a person's heart would be. Participants can partake in an experience called energetic coalescence: they gather in the same spot in the virtual-reality landscape to overlap their diffuse bodies, making it impossible to tell where each person begins and ends. The resulting sense of deep connectedness and ego attenuation mirrors feelings commonly brought about by a psychedelic experience.

[...] To create it, Glowacki took aesthetic inspiration from quantum mechanics -- as he puts it, "where the definition of what's matter and what's energy starts to become blurred." For their paper, Glowacki and his collaborators measured the emotional response Isness-D elicited in 75 participants. They based their measurements on four metrics used in psychedelics research -- the MEQ30 (a mystical experience questionnaire), the ego dissolution inventory scale, the "communitas" scale, and the "inclusion of community in self" scale. Communitas is defined as an experience of intense shared humanity that transcends social structure. Participants' responses were then compared with those given in published, double-blind psychedelics studies. For all four metrics, Isness-D elicited responses indistinguishable from those associated with medium doses of psychedelics. On the mystical experience scale, Isness-D participants reported an experience as intense as that elicited by 20 milligrams of psilocybin or 200 micrograms of LSD, and stronger than that induced by microdoses of either substance. The findings have been published in the journal Nature Scientific Reports.

Polio is back, monkeypox isn't slowing down, COVID-19 is still around -- and now there's more not-so-good news on the infection front: over 200 human diseases could get worse because of climate change, according to a new study. From a report: Researchers have known for a long time that the changing climate affects disease. Warmer temperatures can make regions newly hospitable to disease-carrying mosquitoes, while floods from more frequent storms can carry bacteria in their surges of water. Most research, though, only focused on a handful of threats or one disease at a time. The new study, published in Nature Climate Change, built a comprehensive map of all of the ways various climate hazards could interact with 375 documented human infectious diseases. The authors reviewed over 77,000 scientific articles about those diseases and climate hazards. They found that, of those 375 diseases, 218 could be aggravated by things like heatwaves, rising sea levels, and wildfires.

The study found four main ways climate change exacerbates diseases. First, problems happen when changes cause disease-carrying animals to move closer to people. For example, animal habitats are disrupted by things like wildfires that drive bats and rodents into new areas, increasing the likelihood they'll transmit diseases like Ebola to people. Other research shows that climate change makes viruses more likely to jump from animals to people, as happened with the coronavirus that causes COVID-19. That phenomenon also likely contributed to the 2016 Zika outbreaks.